Watkins, Hugh

Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes

Strawbridge, R. J., Dupuis, J., Prokopenko, I., Barker, A., Ahlqvist, E., Rybin, D., Petrie, J. R., Travers, M. E., Bouatia-Naji, N., Dimas, A. S., et al. (2011) · Diabetes

Genetic Associations and EpidemiologyDiabetes and associated disorders

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Genetic evidence of assortative mating in humans

Robinson, M. R., Kleinman, A., Graff, M., Vinkhuyzen, A. A. E., Couper, D., Miller, M. B., Peyrot, W. J., Abdellaoui, A., Zietsch, B. P., Nolte, I. M., et al. (2017) · Nature Human Behaviour

Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock

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Phenotypic Characterization of Genetically Lowered Human Lipoprotein(a) Levels

Emdin, C. A., Khera, A. V., Natarajan, P., Klarin, D., Won, H.-H., Peloso, G. M., Stitziel, N. O., Nomura, A., Zekavat, S. M., Bick, A. G., et al. (2016) · Journal of the American College of Cardiology

Lipoproteins and Cardiovascular HealthGenetic Associations and Epidemiology

Cited by 244

Association of rare and common variation in the lipoprotein lipase gene with coronary artery disease

Khera, A. V., Won, H.-H., Peloso, G. M., O’Dushlaine, C., Liu, D., Stitziel, N. O., Natarajan, P., Nomura, A., Emdin, C. A., Gupta, N., et al. (2017) · JAMA

Lipid metabolism and disordersLipoproteins and Cardiovascular Health

Cited by 198

Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease

van Meurs, J. B., Pare, G., Schwartz, S. M., Hazra, A., Tanaka, T., Vermeulen, S. H., Cotlarciuc, I., Yuan, X., Mälarstig, A., Bandinelli, S., et al. (2013) · The American Journal of Clinical Nutrition

Folate and B Vitamins ResearchGenetic Associations and Epidemiology

Cited by 198

Preclinical diagnosis of familial hypertrophic cardiomyopathy by genetic analysis of blood lymphocytes

Rosenzweig, A., Watkins, H., Hwang, D.-S., Miri, M., McKenna, W., Traill, T. A., Seidman, J. G., & Seidman, C. E. (1991) · New England Journal of Medicine

Cardiomyopathy and Myosin StudiesGenomics and Rare Diseases

Cited by 181

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

Voight, B. F., Peloso, G. M., Orho-Melander, M., Frikke-Schmidt, R., Barbalic, M., Jensen, M. K., Hindy, G., Hólm, H., Ding, E. L., Johnson, T., et al. (2012) · The Lancet

Genetic Associations and EpidemiologyLipoproteins and Cardiovascular Health

Cited by 148

AMP-Activated Protein Kinase Phosphorylates Cardiac Troponin I and Alters Contractility of Murine Ventricular Myocytes

Oliveira, S. M., Zhang, Y.-H., Solis, R. S., Isackson, H., Bellahcene, M., Yavari, A., Pinter, K., Davies, J. K., Ge, Y., Ashrafian, H., et al. (2012) · Circulation Research

Cardiomyopathy and Myosin StudiesMetabolism, Diabetes, and Cancer

Cited by 86

“Not pathogenic until proven otherwise”: perspectives of UK clinical genomics professionals toward secondary findings in context of a Genomic Medicine Multidisciplinary Team and the 100,000 Genomes Project

Ormondroyd, E., Mackley, M. P., Blair, E., Craft, J., Knight, J. C., Taylor, J. C., Taylor, J., & Watkins, H. (2018) · Genetics in Medicine

Genomics and Rare DiseasesMedical and Health Sciences Research

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Resistance of Dynamin-related Protein 1 Oligomers to Disassembly Impairs Mitophagy, Resulting in Myocardial Inflammation and Heart Failure

Cahill, T. J., Leo, V., Kelly, M., Stockenhuber, A., Kennedy, N. W., Bao, L., Cereghetti, G., Harper, A. R., Czibik, G., Lao, C., et al. (2015) · Journal of Biological Chemistry

Mitochondrial Function and PathologyAutophagy in Disease and Therapy

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The role of vascular myoglobin in nitrite-mediated blood vessel relaxation

Ormerod, J. O. M., Ashrafian, H., Maher, A. R., Arif, S., Steeples, V., Born, G. V. R., Egginton, S., Feelisch, M., Watkins, H., & Frenneaux, M. P. (2011) · Cardiovascular Research

Hemoglobin structure and functionNitric Oxide and Endothelin Effects

Cited by 61

2014 ESC Guidelines on Diagnosis and Management of Hypertrophic Cardiomyopathy

Elliott, P. M., Anastasakis, A., Borger, M. A., Borggrefe, M., Cecchi, F., Charron, P., Hagege, A. A., Lafont, A., Limongelli, G., Mahrholdt, H., et al. (2015) · Revista Española de Cardiología (English Edition)

Coronary Interventions and DiagnosticsAcute Myocardial Infarction Research

Cited by 55

Distribution and Medical Impact of Loss-of-Function Variants in the Finnish Founder Population

Lim, E. T., Würtz, P., Havulinna, A. S., Palta, P., Tukiainen, T., Rehnström, K., Esko, T., Mägi, R., Inouye, M., Lappalainen, T., et al. (2014) · PLoS Genetics

Genetic Associations and EpidemiologyGenomics and Rare Diseases

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Hypertrophic cardiomyopathy detection with artificial intelligence electrocardiography in international cohorts: an external validation study

Siontis, K. C., Wieczorek, M. A., Maanja, M., Hodge, D. O., Kim, H.-K., Lee, H.-J., Lee, H., Lim, J., Park, C. S., Ariga, R., et al. (2024) · European Heart Journal - Digital Health

ECG Monitoring and AnalysisCardiomyopathy and Myosin Studies

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The molecular phenotype of human cardiac myosin associated with hypertrophic obstructive cardiomyopathy

Jacques, A. M., Briceno, N., Messer, A. E., Gallon, C. E., Jalilzadeh, S., Garcia, E., Kikonda-Kanda, G., Goddard, J., Harding, S. E., Watkins, H., et al. (2008) · Cardiovascular Research

Cardiomyopathy and Myosin StudiesCardiac electrophysiology and arrhythmias

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A multi-ancestry genome-wide study incorporating gene–smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure

Sung, Y. J., de las Fuentes, L., Winkler, T. W., Chasman, D. I., Bentley, A. R., Kraja, A. T., Ntalla, I., Warren, H. R., Guo, X., Schwander, K., et al. (2019) · Human Molecular Genetics

Genetic Associations and EpidemiologyBlood Pressure and Hypertension Studies

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De Novo Truncating Mutations in WASF1 Cause Intellectual Disability with Seizures

Ito, Y., Carss, K. J., Duarte, S. T., Hartley, T., Keren, B., Kurian, M. A., Marey, I., Charles, P., Mendonça, C., Nava, C., et al. (2018) · The American Journal of Human Genetics

Genetics and Neurodevelopmental DisordersGenomics and Rare Diseases

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Resistance of dynamin-related protein 1 oligomers to disassembly impairs mitophagy, resulting in myocardial inflammation and heart failure

Cahill, T. J., Leo, V., Kelly, M., Stockenhuber, A., Kennedy, N. W., Bao, L., Cereghetti, G. M., Harper, A. R., Czibik, G., Liao, C., et al. (2016) · Journal of Biological Chemistry

Autophagy in Disease and TherapyMitochondrial Function and Pathology

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