Nolan, Garry P.

Data-Driven Phenotypic Dissection of AML Reveals Progenitor-like Cells that Correlate with Prognosis

Levine, J. H., Simonds, E. F., Bendall, S. C., Davis, K. L., Amir, E.-A. D., Tadmor, M. D., Litvin, O., Fienberg, H. G., Jager, A., Zunder, E. R., et al. (2015) · Cell

Acute Myeloid Leukemia ResearchSingle-cell and spatial transcriptomics

Cited by 2,303

Single-Cell Mass Cytometry of Differential Immune and Drug Responses Across a Human Hematopoietic Continuum

Bendall, S. C., Simonds, E. F., Qiu, P., Amir, E.-A. D., Krutzik, P. O., Finck, R., Bruggner, R. V., Melamed, R., Trejo, A., Ornatsky, O. I., et al. (2011) · Science

Single-cell and spatial transcriptomicsMetabolomics and Mass Spectrometry Studies

Cited by 2,279

The human cell atlas

Regev, A., Teichmann, S. A., Lander, E. S., Amit, I., Benoist, C., Birney, E., Bodenmiller, B., Campbell, P., Carninci, P., Clatworthy, M., et al. (2017) · eLife

Single-cell and spatial transcriptomicsGene Regulatory Network Analysis

Cited by 2,232

Three-dimensional intact-tissue sequencing of single-cell transcriptional states

Wang, X., Allen, W. E., Wright, M. A., Sylwestrak, E. L., Samusik, N., Vesuna, S., Evans, K., Liu, C., Ramakrishnan, C., Liu, J., et al. (2018) · Science

Single-cell and spatial transcriptomicsMolecular Biology Techniques and Applications

Cited by 1,620

viSNE enables visualization of high dimensional single-cell data and reveals phenotypic heterogeneity of leukemia

Amir, E.-A. D., Davis, K. L., Tadmor, M. D., Simonds, E. F., Levine, J. H., Bendall, S. C., Shenfeld, D. K., Krishnaswamy, S., Nolan, G. P., & Pe'er, D. (2013) · Nature Biotechnology

Single-cell and spatial transcriptomicsData Visualization and Analytics

Cited by 1,550

Deep profiling of mouse splenic architecture with CODEX multiplexed imaging

Goltsev, Y., Samusik, N., Kennedy-Darling, J., Bhate, S., Hale, M., Vazquez, G., Black, S., & Nolan, G. P. (2018) · Cell

Single-cell and spatial transcriptomicsCell Image Analysis Techniques

Cited by 1,501

A gut bacterial pathway metabolizes aromatic amino acids into nine circulating metabolites

Dodd, D., Spitzer, M. H., Van Treuren, W., Merrill, B. D., Hryckowian, A. J., Higginbottom, S. K., Le, A., Cowan, T. M., Nolan, G. P., Fischbach, M. A., et al. (2017) · Nature

Gut microbiota and healthTryptophan and brain disorders

Cited by 1,425

Multimodal Analysis of Composition and Spatial Architecture in Human Squamous Cell Carcinoma

Ji, A. L., Rubin, A. J., Thrane, K., Jiang, S., Reynolds, D. L., Meyers, R. M., Guo, M. G., George, B. M., Mollbrink, A., Bergenstråhle, J., et al. (2020) · Cell

Nonmelanoma Skin Cancer StudiesSingle-cell and spatial transcriptomics

Cited by 1,117

Multiplexed ion beam imaging of human breast tumors

Angelo, M., Bendall, S. C., Finck, R., Hale, M. B., Hitzman, C., Borowsky, A. D., Levenson, R. M., Lowe, J. B., Liu, S. D., Zhao, S., et al. (2014) · Nature Medicine

Mass Spectrometry Techniques and ApplicationsIon-surface interactions and analysis

Cited by 1,108

Systemic Immunity Is Required for Effective Cancer Immunotherapy

Spitzer, M. H., Carmi, Y., Reticker-Flynn, N. E., Kwek, S. S., Madhireddy, D., Martins, M. M., Gherardini, P. F., Prestwood, T. R., Chabon, J., Bendall, S. C., et al. (2017) · Cell

Cancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses

Cited by 963

Extracting a cellular hierarchy from high-dimensional cytometry data with SPADE

Qiu, P., Simonds, E. F., Bendall, S. C., Gibbs, K. D., Bruggner, R. V., Linderman, M. D., Sachs, K., Nolan, G. P., & Plevritis, S. K. (2011) · Nature Biotechnology

Single-cell and spatial transcriptomicsCell Image Analysis Techniques

Cited by 956

Single-Cell Trajectory Detection Uncovers Progression and Regulatory Coordination in Human B Cell Development

Bendall, S. C., Davis, K. L., Amir, E.-A. D., Tadmor, M. D., Simonds, E. F., Chen, T. J., Shenfeld, D. K., Nolan, G. P., & Pe’er, D. (2014) · Cell

Single-cell and spatial transcriptomicsT-cell and B-cell Immunology

Cited by 906

Computational solutions to large‐scale data management and analysis

Schadt, E. E., Linderman, M. D., Sorenson, J., Lee, L., & Nolan, G. P. (2010) · Nature Reviews Genetics

Scientific Computing and Data ManagementCloud Computing and Resource Management

Cited by 631

Palladium-based mass tag cell barcoding with a doublet-filtering scheme and single-cell deconvolution algorithm

Zunder, E. R., Finck, R., Behbehani, G. K., Amir, E.-A. D., Krishnaswamy, S., Gonzalez, V. D., Lorang, C. G., Bjornson, Z., Spitzer, M. H., Bodenmiller, B., et al. (2015) · Nature Protocols

Single-cell and spatial transcriptomicsAdvanced Proteomics Techniques and Applications

Cited by 596

The human body at cellular resolution: the NIH Human Biomolecular Atlas Program

HuBMAP Consortium, Writing Group, Snyder, M. P., Lin, S., Posgai, A., Atkinson, M., Regev, A., Rood, J., Rozenblatt-Rosen, O., Gaffney, L., et al. (2019) · Nature

Single-cell and spatial transcriptomicsGenomics and Chromatin Dynamics

Cited by 595

Cytometry by time-of-flight shows combinatorial cytokine expression and virus-specific cell niches within a continuum of CD8+ T cell phenotypes

Newell, E. W., Sigal, N., Bendall, S. C., Nolan, G. P., & Davis, M. M. (2012) · Immunity

T-cell and B-cell ImmunologyImmune Cell Function and Interaction

Cited by 555

Multiplexed mass cytometry profiling of cellular states perturbed by small-molecule regulators

Bodenmiller, B., Zunder, E. R., Finck, R., Chen, T. J., Savig, E. S., Bruggner, R. V., Simonds, E. F., Bendall, S. C., Sachs, K., Krutzik, P. O., et al. (2012) · Nature Biotechnology

Metabolomics and Mass Spectrometry StudiesAdvanced Proteomics Techniques and Applications

Cited by 546

MIFlowCyt: The minimum information about a flow cytometry experiment

Lee, J. A., Spidlen, J., Boyce, K., Cai, J., Crosbie, N., Dalphin, M., Furlong, J., Gasparetto, M., Goldberg, M., Goralczyk, E. M., et al. (2008) · Cytometry Part A

Research Data Management PracticesScientific Computing and Data Management

Cited by 533

Enabling Technologies for Personalized and Precision Medicine

Ho, D., Quake, S. R., McCabe, E. R. B., Chng, W. J., Chow, E. K., Ding, X., Gelb, B. D., Ginsburg, G. S., Hassenstab, J., Ho, C.-M., et al. (2020) · Trends in Biotechnology

Technology and Human Factors in Education and HealthAdvanced Biosensing Techniques and Applications

Cited by 517

The candidate proto-oncogene bcl-3 encodes a transcriptional coactivator that activates through NF-kappa B p50 homodimers.

Fujita, T., Nolan, G. P., Liou, H. C., Scott, M. L., & Baltimore, D. (1993) · Genes & Development

NF-κB Signaling PathwaysGenomics and Chromatin Dynamics

Cited by 409

Single-cell mass cytometry reveals distinct populations of brain myeloid cells in mouse neuroinflammation and neurodegeneration models

Ajami, B., Samusik, N., Wieghofer, P., Ho, P. P., Crotti, A., Bjornson, Z., Prinz, M., Fantl, W. J., Nolan, G. P., & Steinman, L. (2018) · Nature Neuroscience

Neuroinflammation and Neurodegeneration MechanismsMultiple Sclerosis Research Studies

Cited by 338

Highly multiplexed simultaneous detection of RNAs and proteins in single cells

Frei, A. P., Bava, F.-A., Zunder, E. R., Hsieh, E. W. Y., Chen, S.-Y., Nolan, G. P., & Gherardini, P. F. (2016) · Nature Methods

Single-cell and spatial transcriptomicsAdvanced Proteomics Techniques and Applications

Cited by 330

Chemical combination effects predict connectivity in biological systems

Lehár, J., Zimmermann, G. R., Krueger, A. S., Molnar, R. A., Ledell, J. T., Heilbut, A. M., Short, G. F., Giusti, L. C., Nolan, G. P., Magid, O. A., et al. (2007) · Molecular Systems Biology

Gene Regulatory Network AnalysisBioinformatics and Genomic Networks

Cited by 275

Conditional density-based analysis of T cell signaling in single-cell data

Krishnaswamy, S., Spitzer, M. H., Mingueneau, M., Bendall, S. C., Litvin, O., Stone, E., Pe’er, D., & Nolan, G. P. (2014) · Science

Gene Regulatory Network AnalysisSingle-cell and spatial transcriptomics

Cited by 225