Patel, Smita

Clearance of α-Synuclein Oligomeric Intermediates via the Lysosomal Degradation Pathway

Lee, H.-J., Khoshaghideh, F., Patel, S., & Lee, S.-J. (2004) · The Journal of Neuroscience

Parkinson's Disease Mechanisms and TreatmentsAlzheimer's disease research and treatments

Cited by 445

Structural basis for m7G recognition and 2′-O-methyl discrimination in capped RNAs by the innate immune receptor RIG-I

Devarkar, S. C., Wang, C., Miller, M. T., Ramanathan, A., Jiang, F., Khan, A. G., Patel, S. S., & Marcotrigiano, J. (2016) · Proceedings of the National Academy of Sciences

interferon and immune responsesImmune Response and Inflammation

Cited by 357

Role of dopamine D2-like receptors in cocaine self-administration: studies with D2 receptor mutant mice and novel D2 receptor antagonists

Caine, S. B., Negus, S. S., Mello, N. K., Patel, S., Bristow, L., Kulagowski, J., Vallone, D., Saiardi, A., & Borrelli, E. (2002) · The Journal of Neuroscience

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 234

Neuron loss from the hippocampus of Alzheimer's disease exceeds extracellular neurofibrillary tangle formation

Kril, J., Patel, S., Harding, A., & Halliday, G. (2002) · Acta Neuropathologica

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 190

Real-time dynamic single-molecule protein sequencing on an integrated semiconductor device

Reed, B. D., Meyer, M. J., Abramzon, V., Ad, O., Adcock, P., Ahmad, F. R., Alppay, G., Ball, J. A., Beach, J., Belhachemi, D., et al. (2022) · Science

Advanced Fluorescence Microscopy TechniquesMicrofluidic and Capillary Electrophoresis Applications

Cited by 134

Distribution of brain atrophy in behavioral variant frontotemporal dementia

Kril, J. J., Macdonald, V., Patel, S., Png, F., & Halliday, G. M. (2005) · Journal of the Neurological Sciences

Dementia and Cognitive Impairment ResearchAmyotrophic Lateral Sclerosis Research

Cited by 83

Human mitochondrial DNA helicase TWINKLE is both an unwinding and annealing helicase

Sen, D., Nandakumar, D., Tang, G.-Q., & Patel, S. S. (2012) · Journal of Biological Chemistry

DNA Repair MechanismsMitochondrial Function and Pathology

Cited by 63

Kinetics of human mutant tau prion formation in the brains of 2 transgenic mouse lines

Woerman, A. L., Patel, S., Kazmi, S. A., Oehler, A., Freyman, Y., Espiritu, L., Cotter, R., Castaneda, J. A., Olson, S. H., & Prusiner, S. B. (2017) · JAMA Neurology

Alzheimer's disease research and treatmentsPrion Diseases and Protein Misfolding

Cited by 44

Critical Role of a Subdomain of the N-Terminus of the V 1 a Vasopressin Receptor for Binding Agonists but Not Antagonists; Functional Rescue by the Oxytocin Receptor N-Terminus

Hawtin, S. R., Wesley, V. J., Parslow, R. A., Patel, S., & Wheatley, M. (2000) · Biochemistry

Receptor Mechanisms and SignalingNeuropeptides and Animal Physiology

Cited by 32

Structures illustrate step-by-step mitochondrial transcription initiation

Goovaerts, Q., Shen, J., De Wijngaert, B., Basu, U., Patel, S. S., & Das, K. (2023) · Nature

Genomics and Chromatin DynamicsRNA and protein synthesis mechanisms

Cited by 16

Yeast mtDNA transcription initiation in single nucleotide addition steps

Das, K., Goovaerts, Q., Shen, J., De Wijngaert, B., Basu, U., & Patel, S. (2022) · Nature

Genomics and Chromatin DynamicsRNA and protein synthesis mechanisms

Cited by 16

The N-terminal domain of the human mitochondrial helicase Twinkle has DNA binding activity crucial for supporting processive DNA synthesis by Polymerase γ

Johnson, L. C., Singh, A., & Patel, S. S. (2022) · Journal of Biological Chemistry

DNA Repair MechanismsMitochondrial Function and Pathology

Cited by 8

The N-terminal domain of human mitochondrial helicase Twinkle has DNA-binding activity crucial for supporting processive DNA synthesis by polymerase γ

Johnson, L. C., Singh, A., & Patel, S. S. (2023) · Journal of Biological Chemistry

DNA Repair MechanismsMitochondrial Function and Pathology

Cited by 8

Human mitochondrial RNA polymerase structures reveal transcription start site and slippage mechanism

Shen, J., Goovaerts, Q., Ajjugal, Y., De Wijngaert, B., Das, K., & Patel, S. S. (2025) · Molecular Cell

Genomics and Chromatin DynamicsMitochondrial Function and Pathology

Cited by 5