Baes, Myriam

Fatty acid carbon is essential for dNTP synthesis in endothelial cells

Schoors, S., Bruning, U., Missiaen, R., Queiroz, K. C. S., Borgers, G., Elia, I., Zecchin, A., Cantelmo, A. R., Christen, S., Goveia, J., et al. (2015) · Nature

Cancer, Lipids, and MetabolismAngiogenesis and VEGF in Cancer

Cited by 646

Axonal loss and neuroinflammation caused by peroxisome-deficient oligodendrocytes

Kassmann, C. M., Lappe-Siefke, C., Baes, M., Brügger, B., Mildner, A., Werner, H. B., Natt, O., Michaelis, T., Prinz, M., Frahm, J., et al. (2007) · Nature Genetics

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 357

A mouse model for Zellweger syndrome

Baes, M., Gressens, P., Baumgart, E., Carmeliet, P., Casteels, M., Fransen, M., Evrard, P., Fahimi, D., Declercq, P. E., Collen, D., et al. (1997) · Nature Genetics

Metabolism and Genetic DisordersHereditary Neurological Disorders

Cited by 275

The physiological functions of human peroxisomes

Wanders, R. J. A., Baes, M., Ribeiro, D., Ferdinandusse, S., & Waterham, H. R. (2023) · Physiological Reviews

Metabolism and Genetic DisordersLipid metabolism and biosynthesis

Cited by 228

Mitochondrial Alterations Caused by Defective Peroxisomal Biogenesis in a Mouse Model for Zellweger Syndrome (PEX5 Knockout Mouse)

Baumgart, E., Vanhorebeek, I., Grabenbauer, M., Borgers, M., Declercq, P. E., Fahimi, H. D., & Baes, M. (2001) · The American Journal of Pathology

Metabolism and Genetic DisordersMitochondrial Function and Pathology

Cited by 210

Absence of peroxisomes in mouse hepatocytes causes mitochondrial and ER abnormalities†

Dirkx, R., Vanhorebeek, I., Martens, K., Schad, A., Grabenbauer, M., Fahimi, D., Declercq, P., Van Veldhoven, P. P., & Baes, M. (2005) · Hepatology

Metabolism and Genetic DisordersMitochondrial Function and Pathology

Cited by 174

Oligodendroglial fatty acid metabolism as a central nervous system energy reserve

Asadollahi, E., Trevisiol, A., Saab, A. S., Looser, Z. J., Dibaj, P., Ebrahimi, R., Kusch, K., Ruhwedel, T., Möbius, W., Jahn, O., et al. (2024) · Nature Neuroscience

Lipid metabolism and biosynthesisNeurogenesis and neuroplasticity mechanisms

Cited by 130

Absence of functional peroxisomes from mouse CNS causes dysmyelination and axon degeneration

Hulshagen, L., Krysko, O., Bottelbergs, A., Huyghe, S., Klein, R., Van Veldhoven, P. P., De Deyn, P. P., D'Hooge, R., Hartmann, D., & Baes, M. (2008) · The Journal of Neuroscience

Metabolism and Genetic DisordersLysosomal Storage Disorders Research

Cited by 115

Peroxisomal multifunctional protein-2: The enzyme, the patients and the knockout mouse model.

Huyghe, S., Mannaerts, G. P., Baes, M., & Van Veldhoven, P. P. (2006) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Metabolism and Genetic DisordersPeroxisome Proliferator-Activated Receptors

Cited by 91

Neocortical and cerebellar developmental abnormalities in conditions of selective elimination of peroxisomes from brain or from liver

Krysko, O., Hulshagen, L., Janssen, A., Schütz, G., Klein, R., De Bruycker, M., Espeel, M., Gressens, P., & Baes, M. (2007) · Journal of Neuroscience Research

Neurogenesis and neuroplasticity mechanismsMetabolism and Genetic Disorders

Cited by 90

Axonal integrity in the absence of functional peroxisomes from projection neurons and astrocytes

Bottelbergs, A., Verheijden, S., Hulshagen, L., Gutmann, D. H., Goebbels, S., Nave, K., Kassmann, C., & Baes, M. (2010) · Glia

Metabolism and Genetic DisordersHereditary Neurological Disorders

Cited by 78

Peroxisome deficiency but not the defect in ether lipid synthesis causes activation of the innate immune system and axonal loss in the central nervous system

Bottelbergs, A., Verheijden, S., Van Veldhoven, P. P., Just, W., Devos, R., & Baes, M. (2012) · Journal of Neuroinflammation

Neuroinflammation and Neurodegeneration MechanismsLysosomal Storage Disorders Research

Cited by 66

Neuronal migration depends on intact peroxisomal function in brain and in extraneuronal tissues

Janssen, A., Gressens, P., Grabenbauer, M., Baumgart, E., Schad, A., Vanhorebeek, I., Brouwers, A., Declercq, P. E., Fahimi, D., Evrard, P., et al. (2003) · The Journal of Neuroscience

Metabolism and Genetic DisordersNeurogenesis and neuroplasticity mechanisms

Cited by 65

Peroxisomes, myelination, and axonal integrity in the CNS

Baes, M., & Aubourg, P. (2009) · The Neuroscientist

Metabolism and Genetic DisordersHereditary Neurological Disorders

Cited by 65

Peroxisomal multifunctional protein-2 deficiency causes neuroinflammation and degeneration of Purkinje cells independent of very long chain fatty acid accumulation

Verheijden, S., Bottelbergs, A., Krysko, O., Krysko, D. V., Beckers, L., De Munter, S., Van Veldhoven, P. P., Wyns, S., Kulik, W., Nave, K.-A., et al. (2013) · Neurobiology of Disease

Metabolism and Genetic DisordersGenetic Neurodegenerative Diseases

Cited by 54

A role for myelin-associated peroxisomes in maintaining paranodal loops and axonal integrity

Kassmann, C. M., Quintes, S., Rietdorf, J., Möbius, W., Sereda, M. W., Nientiedt, T., Saher, G., Baes, M., & Nave, K.-A. (2011) · FEBS Letters

Hereditary Neurological DisordersMultiple Sclerosis Research Studies

Cited by 52

Prenatal and postnatal development of peroxisomal lipid-metabolizing pathways in the mouse

HUYGHE, S., CASTEELS, M., JANSSEN, A., MEULDERS, L., MANNAERTS, G. P., DECLERCQ, P. E., VELDHOVEN, P. P. V., & BAES, M. (2001) · Biochemical Journal

Metabolism and Genetic DisordersLipid metabolism and biosynthesis

Cited by 48

Developmental changes of bile acid composition and conjugation in L- and D-bifunctional protein single and double knockout mice

Ferdinandusse, S., Denis, S., Overmars, H., Van Eeckhoudt, L., Van Veldhoven, P. P., Duran, M., Wanders, R. J. A., & Baes, M. (2005) · Journal of Biological Chemistry

Cholesterol and Lipid MetabolismMetabolism and Genetic Disorders

Cited by 47

Peroxisomal dysfunctions cause lysosomal storage and axonal Kv1 channel redistribution in peripheral neuropathy

Kleinecke, S., Richert, S., de Hoz, L., Brügger, B., Kungl, T., Asadollahi, E., Quintes, S., Blanz, J., McGonigal, R., Naseri, K., et al. (2017) · eLife

Hereditary Neurological DisordersLysosomal Storage Disorders Research

Cited by 46

Identification of a chronic non‐neurodegenerative microglia activation state in a mouse model of peroxisomal β‐oxidation deficiency

Verheijden, S., Beckers, L., Casazza, A., Butovsky, O., Mazzone, M., & Baes, M. (2015) · Glia

Neuroinflammation and Neurodegeneration MechanismsMultiple Sclerosis Research Studies

Cited by 40

Microglia lacking a peroxisomal β-oxidation enzyme chronically alter their inflammatory profile without evoking neuronal and behavioral deficits

Beckers, L., Geric, I., Stroobants, S., Beel, S., Van Damme, P., D’Hooge, R., & Baes, M. (2019) · Journal of Neuroinflammation

Neuroinflammation and Neurodegeneration MechanismsNeurological Disease Mechanisms and Treatments

Cited by 30

Combined deficiency of peroxisomal β-oxidation and ether lipid synthesis in mice causes only minor cortical neuronal migration defects but severe hypotonia

Krysko, O., Bottelbergs, A., Veldhoven, P. V., & Baes, M. (2010) · Molecular Genetics and Metabolism

Metabolism and Genetic DisordersLysosomal Storage Disorders Research

Cited by 17

Phytol is lethal for Amacr-deficient mice

Selkälä, E. M., Nair, R. R., Schmitz, W., Kvist, A.-P., Baes, M., Hiltunen, J. K., & Autio, K. J. (2015) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Metabolism and Genetic DisordersCholesterol and Lipid Metabolism

Cited by 11