Chen, Chia-Yen

Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases

Verbanck, M., Chen, C.-Y., Neale, B., & Do, R. (2018) · Nature Genetics

Genetic Associations and EpidemiologyAdvanced Causal Inference Techniques

Cited by 8,591

FinnGen provides genetic insights from a well-phenotyped isolated population

Kurki, M. I., Karjalainen, J., Palta, P., Sipilä, T. P., Kristiansson, K., Donner, K. M., Reeve, M. P., Laivuori, H., Aavikko, M., Kaunisto, M. A., et al. (2023) · Nature

Genetic Associations and EpidemiologyGenomics and Rare Diseases

Cited by 4,233

Mapping genomic loci implicates genes and synaptic biology in schizophrenia

Trubetskoy, V., Pardiñas, A. F., Qi, T., Panagiotaropoulou, G., Awasthi, S., Bigdeli, T. B., Bryois, J., Chen, C.-Y., Dennison, C. A., Hall, L. S., et al. (2022) · Nature

Schizophrenia research and treatmentGenetic Associations and Epidemiology

Cited by 2,964

Polygenic prediction via Bayesian regression and continuous shrinkage priors

Ge, T., Chen, C.-Y., Ni, Y., Feng, Y.-C. A., & Smoller, J. W. (2019) · Nature Communications

Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock

Cited by 1,922

Plasma proteomic associations with genetics and health in the UK Biobank

Sun, B. B., Chiou, J., Traylor, M., Benner, C., Hsu, Y.-H., Richardson, T. G., Surendran, P., Mahajan, A., Robins, C., Vasquez-Grinnell, S. G., et al. (2023) · Nature

Genetic Associations and EpidemiologyBioinformatics and Genomic Networks

Cited by 1,880

Genome-wide Association Studies in Ancestrally Diverse Populations: Opportunities, Methods, Pitfalls, and Recommendations

Peterson, R. E., Kuchenbaecker, K., Walters, R. K., Chen, C.-Y., Popejoy, A. B., Periyasamy, S., Lam, M., Iyegbe, C., Strawbridge, R. J., Brick, L., et al. (2019) · Cell

Genetic Associations and EpidemiologyRace, Genetics, and Society

Cited by 797

Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

23and Me Research Team, Karlsson Linnér, R., eQTLgen Consortium, International Cannabis Consortium, Social Science Genetic Association Consortium, Biroli, P., Kong, E., Meddens, S. F. W., Wedow, R., Fontana, M. A., et al. (2019) · Nature Genetics

Genetic Associations and EpidemiologyNeurotransmitter Receptor Influence on Behavior

Cited by 756

Assessment of Bidirectional Relationships Between Physical Activity and Depression Among Adults: A 2-Sample Mendelian Randomization Study

Choi, K. W., Chen, C.-Y., Stein, M. B., Klimentidis, Y. C., Wang, M.-J., Koenen, K. C., Smoller, J. W., & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2019) · JAMA Psychiatry

Physical Activity and HealthGenetic Associations and Epidemiology

Cited by 744

Improving polygenic prediction in ancestrally diverse populations

Ruan, Y., Lin, Y.-F., Feng, Y.-C. A., Chen, C.-Y., Lam, M., Guo, Z., Initiatives, S. G. A., Ahn, Y. M., Akiyama, K., Arai, M., et al. (2022) · Nature Genetics

Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock

Cited by 707

Comparative genetic architectures of schizophrenia in East Asian and European populations

Schizophrenia Working Group of the Psychiatric Genomics Consortium, Lam, M., Indonesia Schizophrenia Consortium, Genetic REsearch on schizophreniA neTwork-China and the Netherlands (GREAT-CN), Chen, C.-Y., Li, Z., Martin, A. R., Bryois, J., Ma, X., Gaspar, H., et al. (2019) · Nature Genetics

Schizophrenia research and treatmentGenetic Associations and Epidemiology

Cited by 655

International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci

Nievergelt, C. M., Maihofer, A. X., Klengel, T., Atkinson, E. G., Chen, C.-Y., Choi, K. W., Coleman, J. R. I., Dalvie, S., Duncan, L. E., Gelernter, J., et al. (2019) · Nature Communications

Posttraumatic Stress Disorder ResearchGenetic Associations and Epidemiology

Cited by 635

Advancing human genetics research and drug discovery through exome sequencing of the UK Biobank

Szustakowski, J. D., Balasubramanian, S., Kvikstad, E., Khalid, S., Bronson, P. G., Sasson, A., Wong, E., Liu, D., Wade Davis, J., Haefliger, C., et al. (2021) · Nature Genetics

Genetic Associations and EpidemiologyGenomics and Rare Diseases

Cited by 401

Brain expression quantitative trait locus and network analyses reveal downstream effects and putative drivers for brain-related diseases

de Klein, N., Tsai, E. A., Vochteloo, M., Baird, D., Huang, Y., Chen, C.-Y., van Dam, S., Oelen, R., Deelen, P., Bakker, O. B., et al. (2023) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 272

Evaluating the cardiovascular safety of sclerostin inhibition using evidence from meta-analysis of clinical trials and human genetics

Bovijn, J., Krebs, K., Chen, C.-Y., Boxall, R., Censin, J. C., Ferreira, T., Pulit, S. L., Glastonbury, C. A., Laber, S., Millwood, I. Y., et al. (2020) · Science Translational Medicine

Bone health and osteoporosis researchGenetic Associations and Epidemiology

Cited by 119

Fine-mapping across diverse ancestries drives the discovery of putative causal variants underlying human complex traits and diseases

Yuan, K., Longchamps, R. J., Pardiñas, A. F., Yu, M., Chen, T.-T., Lin, S.-C., Chen, Y., Lam, M., Liu, R., Xia, Y., et al. (2023) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 94

Genetic risk variants for social anxiety

Stein, M. B., Chen, C., Jain, S., Jensen, K. P., He, F., Heeringa, S. G., Kessler, R. C., Maihofer, A., Nock, M. K., Ripke, S., et al. (2017) · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics

Genetic Associations and EpidemiologyAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Cited by 72

Prospective study of polygenic risk, protective factors, and incident depression following combat deployment in US Army soldiers

Choi, K. W., Chen, C.-Y., Ursano, R. J., Sun, X., Jain, S., Kessler, R. C., Koenen, K. C., Wang, M.-J., Wynn, G. H., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, et al. (2020) · Psychological Medicine

Genetic Associations and EpidemiologyResilience and Mental Health

Cited by 33

Shared genetic architectures of educational attainment in East Asian and European populations

Chen, T.-T., Kim, J., Lam, M., Chuang, Y.-F., Chiu, Y.-L., Lin, S.-C., Jung, S.-H., Kim, B., Kim, S., Cho, C., et al. (2024) · Nature Human Behaviour

Genetic Associations and EpidemiologyCognitive Abilities and Testing

Cited by 18