Hnisz, Denes

Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes

Whyte, W. A., Orlando, D. A., Hnisz, D., Abraham, B. J., Lin, C. Y., Kagey, M. H., Rahl, P. B., Lee, T. I., & Young, R. A. (2013) · Cell

Genomics and Chromatin DynamicsPluripotent Stem Cells Research

Cited by 4,143

Super-enhancers in the control of cell identity and disease

Hnisz, D., Abraham, B. J., Lee, T. I., Lau, A., Saint-André, V., Sigova, A. A., Hoke, H. A., & Young, R. A. (2013) · Cell

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 3,662

Coactivator condensation at super-enhancers links phase separation and gene control

Sabari, B. R., Dall’Agnese, A., Boija, A., Klein, I. A., Coffey, E. L., Shrinivas, K., Abraham, B. J., Hannett, N. M., Zamudio, A. V., Manteiga, J. C., et al. (2018) · Science

Genomics and Chromatin DynamicsRNA Research and Splicing

Cited by 2,595

A Phase Separation Model for Transcriptional Control

Hnisz, D., Shrinivas, K., Young, R. A., Chakraborty, A. K., & Sharp, P. A. (2017) · Cell

Genomics and Chromatin DynamicsGene Regulatory Network Analysis

Cited by 1,753

Activation of proto-oncogenes by disruption of chromosome neighborhoods

Hnisz, D., Weintraub, A. S., Day, D. S., Valton, A.-L., Bak, R. O., Li, C. H., Goldmann, J., Lajoie, B. R., Fan, Z. P., Sigova, A. A., et al. (2016) · Science

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 1,042

YY1 Is a Structural Regulator of Enhancer-Promoter Loops

Weintraub, A. S., Li, C. H., Zamudio, A. V., Sigova, A. A., Hannett, N. M., Day, D. S., Abraham, B. J., Cohen, M. A., Nabet, B., Buckley, D. L., et al. (2017) · Cell

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 992

Control of cell identity genes occurs in insulated neighborhoods in mammalian chromosomes

Dowen, J. M., Fan, Z. P., Hnisz, D., Ren, G., Abraham, B. J., Zhang, L. N., Weintraub, A. S., Schuijers, J., Lee, T. I., Zhao, K., et al. (2014) · Cell

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 884

Convergence of Developmental and Oncogenic Signaling Pathways at Transcriptional Super-Enhancers

Hnisz, D., Schuijers, J., Lin, C. Y., Weintraub, A. S., Abraham, B. J., Lee, T. I., Bradner, J. E., & Young, R. A. (2015) · Molecular Cell

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 476

Insulated Neighborhoods: Structural and Functional Units of Mammalian Gene Control

Hnisz, D., Day, D. S., & Young, R. A. (2016) · Cell

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 420

3D Chromosome Regulatory Landscape of Human Pluripotent Cells

Ji, X., Dadon, D. B., Powell, B. E., Fan, Z. P., Borges-Rivera, D., Shachar, S., Weintraub, A. S., Hnisz, D., Pegoraro, G., Lee, T. I., et al. (2016) · Cell Stem Cell

Genomics and Chromatin DynamicsPluripotent Stem Cells Research

Cited by 400

The Set3/Hos2 Histone Deacetylase Complex Attenuates cAMP/PKA Signaling to Regulate Morphogenesis and Virulence of Candida albicans

Hnisz, D., Majer, O., Frohner, I. E., Komnenovic, V., & Kuchler, K. (2010) · PLoS Pathogens

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 124

A Histone Deacetylase Adjusts Transcription Kinetics at Coding Sequences during Candida albicans Morphogenesis

Hnisz, D., Bardet, A. F., Nobile, C. J., Petryshyn, A., Glaser, W., Schöck, U., Stark, A., & Kuchler, K. (2012) · PLoS Genetics

Fungal and yeast genetics researchGenomics and Chromatin Dynamics

Cited by 100

A Histone Deacetylase Complex Mediates Biofilm Dispersal and Drug Resistance in Candida albicans

Nobile, C. J., Fox, E. P., Hartooni, N., Mitchell, K. F., Hnisz, D., Andes, D. R., Kuchler, K., & Johnson, A. D. (2014) · mBio

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 87

Rational optimization of a transcription factor activation domain inhibitor

Basu, S., Martínez-Cristóbal, P., Frigolé-Vivas, M., Pesarrodona, M., Lewis, M., Szulc, E., Bañuelos, C. A., Sánchez-Zarzalejo, C., Bielskutė, S., Zhu, J., et al. (2023) · Nature Structural & Molecular Biology

Prostate Cancer Treatment and ResearchProtein Structure and Dynamics

Cited by 83

Targeting Chromatin in Fungal Pathogens as A Novel Therapeutic Strategy: Histone Modification Gets Infectious

Hnisz, D., Tscherner, M., & Kuchler, K. (2011) · Epigenomics

Genomics and Chromatin DynamicsFungal Infections and Studies

Cited by 14