Lachin, John M.

Empagliflozin and Progression of Kidney Disease in Type 2 Diabetes

Wanner, C., Inzucchi, S. E., Lachin, J. M., Fitchett, D., von Eynatten, M., Mattheus, M., Johansen, O. E., Woerle, H. J., Broedl, U. C., & Zinman, B. (2016) · New England Journal of Medicine

Chronic Kidney Disease and DiabetesDiabetes Treatment and Management

Cited by 3,655

Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy

Kahn, S. E., Haffner, S. M., Heise, M. A., Herman, W. H., Holman, R. R., Jones, N. P., Kravitz, B. G., Lachin, J. M., O'Neill, M. C., Zinman, B., et al. (2006) · New England Journal of Medicine

Diabetes Treatment and ManagementDiabetes Management and Research

Cited by 2,962

Effect of Sitagliptin on Cardiovascular Outcomes in Type 2 Diabetes

Green, J. B., Bethel, M. A., Armstrong, P. W., Buse, J. B., Engel, S. S., Garg, J., Josse, R., Kaufman, K. D., Koglin, J., Korn, S., et al. (2015) · New England Journal of Medicine

Diabetes Treatment and ManagementDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 2,577

Effect of weight loss with lifestyle intervention on risk of diabetes

Hamman, R. F., Wing, R. R., Edelstein, S. L., Lachin, J. M., Bray, G. A., Delahanty, L., Hoskin, M., Kriska, A. M., Mayer-Davis, E. J., Pi-Sunyer, X., et al. (2006) · Diabetes Care

Diabetes, Cardiovascular Risks, and LipoproteinsObesity, Physical Activity, Diet

Cited by 1,344

Rituximab, B-lymphocyte depletion, and preservation of beta-cell function

Pescovitz, M. D., Greenbaum, C. J., Krause-Steinrauf, H., Becker, D. J., Gitelman, S. E., Goland, R., Gottlieb, P. A., Marks, J. B., McGee, P. F., Moran, A. M., et al. (2009) · New England Journal of Medicine

Diabetes and associated disordersT-cell and B-cell Immunology

Cited by 1,093

Introduction to sample size determination and power analysis for clinical trials

Lachin, J. M. (1981) · Controlled Clinical Trials

Statistical Methods in Clinical TrialsStatistical Methods in Epidemiology

Cited by 1,012

Heart failure outcomes with empagliflozin in patients with type 2 diabetes at high cardiovascular risk: results of the EMPA-REG OUTCOME ® trial

Fitchett, D., Zinman, B., Wanner, C., Lachin, J. M., Hantel, S., Salsali, A., Johansen, O. E., Woerle, H. J., Broedl, U. C., & Inzucchi, S. E. (2016) · European Heart Journal

Diabetes Treatment and ManagementHeart Failure Treatment and Management

Cited by 907

How does empagliflozin reduce cardiovascular mortality? Insights from a mediation analysis of the EMPA-REG OUTCOME Trial

Inzucchi, S. E., Zinman, B., Fitchett, D., Wanner, C., Ferrannini, E., Schumacher, M., Schmoor, C., Ohneberg, K., Johansen, O. E., George, J. T., et al. (2018) · Diabetes Care

Diabetes Treatment and ManagementHeart Failure Treatment and Management

Cited by 740

Statistical Considerations in the Intent-to-Treat Principle

Lachin, J. M. (2000) · Controlled Clinical Trials

Statistical Methods in Clinical TrialsStatistical Methods and Bayesian Inference

Cited by 652

Differences in A1c by race and ethnicity among patients with impaired glucose tolerance in the Diabetes Prevention Program

Herman, W. H., Ma, Y., Uwaifo, G., Haffner, S., Kahn, S. E., Horton, E. S., Lachin, J. M., Montez, M. G., Brenneman, T., Barrett-Connor, E., et al. (2007) · Diabetes Care

Diabetes, Cardiovascular Risks, and LipoproteinsDiabetes Management and Research

Cited by 574

Effect of Glycemic Exposure on the Risk of Microvascular Complications in the Diabetes Control and Complications Trial—Revisited

Lachin, J. M., Genuth, S., Nathan, D. M., Zinman, B., Rutledge, B. N., & for the DCCT/EDIC Research Group (2008) · Diabetes

Diabetes Management and ResearchDiabetes Treatment and Management

Cited by 555

Rosiglitazone-Associated Fractures in Type 2 Diabetes

Kahn, S. E., Zinman, B., Lachin, J. M., Haffner, S. M., Herman, W. H., Holman, R. R., Kravitz, B. G., Yu, D., Heise, M. A., Aftring, R. P., et al. (2008) · Diabetes Care

Diabetes Treatment and ManagementBone health and osteoporosis research

Cited by 537

C-Peptide Is the Appropriate Outcome Measure for Type 1 Diabetes Clinical Trials to Preserve β-Cell Function

Palmer, J. P., Fleming, G. A., Greenbaum, C. J., Herold, K. C., Jansa, L. D., Kolb, H., Lachin, J. M., Polonsky, K. S., Pozzilli, P., Skyler, J. S., et al. (2004) · Diabetes

Diabetes and associated disordersDiabetes Management and Research

Cited by 491

Empagliflozin and clinical outcomes in patients with type 2 diabetes mellitus, established cardiovascular disease, and chronic kidney disease

Wanner, C., Lachin, J. M., Inzucchi, S. E., Fitchett, D., Mattheus, M., George, J., Woerle, H. J., Broedl, U. C., von Eynatten, M., & Zinman, B. (2018) · Circulation

Diabetes Treatment and ManagementChronic Kidney Disease and Diabetes

Cited by 469

Skin collagen glycation, glycoxidation, and crosslinking are lower in subjects with long-term intensive versus conventional therapy of type 1 diabetes: relevance of glycated collagen products versus HbA1c as markers of diabetic complications. DCCT Skin Collagen Ancillary Study Group. Diabetes Control and Complications Trial

Monnier, V. M., Bautista, O., Kenny, D., Sell, D. R., Fogarty, J., Dahms, W., Cleary, P. A., Lachin, J., & Genuth, S. (1999) · Diabetes

Advanced Glycation End Products researchDiabetes Management and Research

Cited by 469

Association between 7 years of intensive treatment of type 1 diabetes and long-term mortality

Orchard, T. J., Nathan, D. M., Zinman, B., Cleary, P., Brillon, D., Backlund, J.-Y. C., & Lachin, J. M. (2015) · JAMA

Diabetes Management and ResearchDiabetes Treatment and Management

Cited by 437

Change in albuminuria as a surrogate endpoint for progression of kidney disease: a meta-analysis of treatment effects in randomised clinical trials

Heerspink, H. J. L., Greene, T., Tighiouart, H., Gansevoort, R. T., Coresh, J., Simon, A. L., Chan, T. M., Hou, F. F., Lewis, J. B., Locatelli, F., et al. (2019) · The Lancet Diabetes & Endocrinology

Chronic Kidney Disease and DiabetesStatistical Methods in Clinical Trials

Cited by 397

Fallacies of last observation carried forward analyses

Lachin, J. M. (2016) · Clinical Trials

Statistical Methods and Bayesian InferenceStatistical Methods in Clinical Trials

Cited by 328

Properties of permuted-block randomization in clinical trials

Matts, J. P., & Lachin, J. M. (1988) · Controlled Clinical Trials

Statistical Methods in Clinical TrialsOptimal Experimental Design Methods

Cited by 321

Fall in C-Peptide During First 2 Years From Diagnosis

Greenbaum, C. J., Beam, C. A., Boulware, D., Gitelman, S. E., Gottlieb, P. A., Herold, K. C., Lachin, J. M., McGee, P., Palmer, J. P., Pescovitz, M. D., et al. (2012) · Diabetes

Diabetes and associated disordersDiabetes Management and Research

Cited by 319

Effects of Prior Intensive Insulin Therapy on Cardiac Autonomic Nervous System Function in Type 1 Diabetes Mellitus: The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study (DCCT/EDIC)

Pop-Busui, R., Low, P. A., Waberski, B. H., Martin, C. L., Albers, J. W., Feldman, E. L., Sommer, C., Cleary, P. A., Lachin, J. M., & Herman, W. H. (2009) · Circulation

Diabetes Management and ResearchHeart Rate Variability and Autonomic Control

Cited by 310

Properties of the urn randomization in clinical trials

Wei, L. J., & Lachin, J. M. (1988) · Controlled Clinical Trials

Statistical Methods in Clinical TrialsOptimal Experimental Design Methods

Cited by 308

Development and progression of renal insufficiency with and without albuminuria in adults with type 1 diabetes in the Diabetes Control and Complications Trial and the Epidemiology of Diabetes Interventions and Complications study

Molitch, M. E., Steffes, M., Sun, W., Rutledge, B., Cleary, P., de Boer, I. H., Zinman, B., Lachin, J., & for the Epidemiology of Diabetes Interventions and Complications (EDIC) Study Group (2010) · Diabetes Care

Chronic Kidney Disease and DiabetesDiabetes Management and Research

Cited by 306

Impact of C-peptide preservation on metabolic and clinical outcomes in the Diabetes Control and Complications Trial

Lachin, J. M., McGee, P., Palmer, J. P., & for the DCCT/EDIC Research Group (2014) · Diabetes

Diabetes Management and ResearchDiabetes Treatment and Management

Cited by 283