Caughman, S. Wright

Iron-Responsive Elements: Regulatory RNA Sequences That Control mRNA Levels and Translation

Casey, J. L., Hentze, M. W., Koeller, D. M., Caughman, S. W., Rouault, T. A., Klausner, R. D., & Harford, J. B. (1988) · Science

Iron Metabolism and DisordersRNA and protein synthesis mechanisms

Cited by 709

Identification of the iron-responsive element for the translational regulation of human ferritin mRNA

Hentze, M. W., Caughman, S. W., Rouault, T. A., Barriocanal, J. G., Dancis, A., Harford, J. B., & Klausner, R. D. (1987) · Science

Iron Metabolism and DisordersRNA and protein synthesis mechanisms

Cited by 571

Binding of a Cytosolic Protein to the Iron-Responsive Element of Human Ferritin Messenger RNA

Rouault, T. A., Hentze, M. W., Caughman, S. W., Harford, J. B., & Klausner, R. D. (1988) · Science

Iron Metabolism and DisordersRNA and protein synthesis mechanisms

Cited by 351

A cis-acting element is necessary and sufficient for translational regulation of human ferritin expression in response to iron.

Hentze, M. W., Rouault, T. A., Caughman, S. W., Dancis, A., Harford, J. B., & Klausner, R. D. (1987) · Proceedings of the National Academy of Sciences

Iron Metabolism and DisordersRNA and protein synthesis mechanisms

Cited by 249

Translational repression by a complex between the iron‐responsive element of ferritin mRNA and its specific cytoplasmic binding protein is position‐dependent in vivo.

Goossen, B., Caughman, S. W., Harford, J. B., Klausner, R. D., & Hentze, M. W. (1990) · The EMBO Journal

Iron Metabolism and DisordersRNA and protein synthesis mechanisms

Cited by 144

A model for the structure and functions of iron-responsive elements

Hentze, M. W., Caughman, S. W., Casey, J. L., Kodier, D. M., Rouault, T. A., Harford, J. B., & Klausner, R. D. (1988) · Gene

Iron Metabolism and DisordersRNA and protein synthesis mechanisms

Cited by 116

The iron-responsive element is the single element responsible for iron-dependent translational regulation of ferritin biosynthesis: evidence for function as the binding site for a translational repressor.

Caughman, S. W., Hentze, M. W., Rouault, T. A., Harford, J. B., & Klausner, R. D. (1988) · Journal of Biological Chemistry

Iron Metabolism and DisordersRNA and protein synthesis mechanisms

Cited by 85