Ikram, M. Arfan

Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores

de Rojas, I., Moreno-Grau, S., Tesi, N., Grenier-Boley, B., Andrade, V., Jansen, I. E., Pedersen, N. L., Stringa, N., Zettergren, A., Hernández, I., et al. (2021) · Nature Communications

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 324

Antihypertensive medications and risk for incident dementia and Alzheimer's disease: a meta-analysis of individual participant data from prospective cohort studies

Ding, J., Davis-Plourde, K. L., Sedaghat, S., Tully, P. J., Wang, W., Phillips, C., Pase, M. P., Himali, J. J., Gwen Windham, B., Griswold, M., et al. (2020) · The Lancet Neurology

Dementia and Cognitive Impairment ResearchBlood Pressure and Hypertension Studies

Cited by 312

Novel genetic loci associated with hippocampal volume

Hibar, D. P., Adams, H. H. H., Jahanshad, N., Chauhan, G., Stein, J. L., Hofer, E., Renteria, M. E., Bis, J. C., Arias-Vasquez, A., Ikram, M. K., et al. (2017) · Nature Communications

Genetic Associations and EpidemiologyMemory and Neural Mechanisms

Cited by 299

Reference values for white blood-cell-based inflammatory markers in the Rotterdam Study: a population-based prospective cohort study

Fest, J., Ruiter, R., Ikram, M. A., Voortman, T., van Eijck, C. H. J., & Stricker, B. H. (2018) · Scientific Reports

Inflammatory Biomarkers in Disease PrognosisClinical Laboratory Practices and Quality Control

Cited by 297

A novel Alzheimer disease locus located near the gene encoding tau protein

Jun, G., Ibrahim-Verbaas, C. A., Vronskaya, M., Lambert, J.-C., Chung, J., Naj, A. C., Kunkle, B. W., Wang, L.-S., Bis, J. C., Bellenguez, C., et al. (2016) · Molecular Psychiatry

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 297

Coronary heart disease, heart failure, and the risk of dementia: a systematic review and meta-analysis

Wolters, F. J., Segufa, R. A., Darweesh, S. K. L., Bos, D., Ikram, M. A., Sabayan, B., Hofman, A., & Sedaghat, S. (2018) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchCardiovascular Health and Risk Factors

Cited by 293

Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation

Teumer, A., Chaker, L., Groeneweg, S., Li, Y., Di Munno, C., Barbieri, C., Schultheiss, U. T., Traglia, M., Ahluwalia, T. S., Akiyama, M., et al. (2018) · Nature Communications

Thyroid Disorders and TreatmentsGenetic Associations and Epidemiology

Cited by 280

Association Between Atrial Fibrillation and Dementia in the General Population

de Bruijn, R. F. A. G., Heeringa, J., Wolters, F. J., Franco, O. H., Stricker, B. H. C., Hofman, A., Koudstaal, P. J., & Ikram, M. A. (2015) · JAMA Neurology

Dementia and Cognitive Impairment ResearchAtrial Fibrillation Management and Outcomes

Cited by 280

Sarcopenia and Sarcopenic Obesity and Mortality Among Older People

Benz, E., Pinel, A., Guillet, C., Capel, F., Pereira, B., De Antonio, M., Pouget, M., Cruz-Jentoft, A. J., Eglseer, D., Topinkova, E., et al. (2024) · JAMA Network Open

Nutrition and Health in AgingFrailty in Older Adults

Cited by 261

Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation

Bis, J. C., Jian, X., Kunkle, B. W., Chen, Y., Hamilton-Nelson, K. L., Bush, W. S., Salerno, W. J., Lancour, D., Ma, Y., Renton, A. E., et al. (2020) · Molecular Psychiatry

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 248

Inflammatory markers and the risk of dementia and Alzheimer's disease: a meta-analysis

Darweesh, S. K. L., Wolters, F. J., Ikram, M. A., de Wolf, F., Bos, D., & Hofman, A. (2018) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 244

Common variation in PHACTR1 is associated with susceptibility to cervical artery dissection

International Stroke Genetics Consortium, Debette, S., the CADISP group, Kamatani, Y., Metso, T. M., Kloss, M., Chauhan, G., Engelter, S. T., Pezzini, A., Thijs, V., et al. (2015) · Nature Genetics

Cerebrovascular and Carotid Artery DiseasesGenetic Associations and Epidemiology

Cited by 231

Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer’s disease

Holstege, H., Hulsman, M., Charbonnier, C., Grenier-Boley, B., Quenez, O., Grozeva, D., van Rooij, J. G. J., Sims, R., Ahmad, S., Amin, N., et al. (2022) · Nature Genetics

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 226

Modifiable Lifestyle Factors in Dementia: A Systematic Review of Longitudinal Observational Cohort Studies

Di Marco, L. Y., Marzo, A., Muñoz-Ruiz, M., Ikram, M. A., Kivipelto, M., Ruefenacht, D., Venneri, A., Soininen, H., Wanke, I., Ventikos, Y. A., et al. (2014) · Journal of Alzheimer's Disease

Dementia and Cognitive Impairment ResearchNutritional Studies and Diet

Cited by 215

Tract-specific white matter degeneration in aging. The Rotterdam Study

de Groot, M., Ikram, M. A., Akoudad, S., Krestin, G. P., Hofman, A., van der Lugt, A., Niessen, W. J., & Vernooij, M. W. (2015) · Alzheimer's & Dementia

Advanced Neuroimaging Techniques and ApplicationsCerebrovascular and genetic disorders

Cited by 211

Improving alignment in Tract-based spatial statistics: evaluation and optimization of image registration

de Groot, M., Vernooij, M. W., Klein, S., Ikram, M. A., Vos, F. M., Smith, S. M., Niessen, W. J., & Andersson, J. L. R. (2013) · NeuroImage

Advanced Neuroimaging Techniques and ApplicationsMedical Image Segmentation Techniques

Cited by 205

The Role of Adiposity in Cardiometabolic Traits: A Mendelian Randomization Analysis

Fall, T., Hägg, S., Mägi, R., Ploner, A., Fischer, K., Horikoshi, M., Sarin, A.-P., Thorleifsson, G., Ladenvall, C., Kals, M., et al. (2013) · PLoS Medicine

Genetic Associations and EpidemiologyAdipokines, Inflammation, and Metabolic Diseases

Cited by 203

Nature as a Trialist?: Deconstructing the Analogy Between Mendelian Randomization and Randomized Trials

Swanson, S. A., Tiemeier, H., Ikram, M. A., & Hernán, M. A. (2017) · Epidemiology

Advanced Causal Inference TechniquesGenetic Associations and Epidemiology

Cited by 202

Convergent genetic and expression data implicate immunity in Alzheimer's disease

International Genomics of Alzheimer's Disease Consortium (IGAP), Jones, L., Lambert, J., Wang, L., Choi, S., Harold, D., Vedernikov, A., Escott‐Price, V., Stone, T., Richards, A., et al. (2015) · Alzheimer's & Dementia

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 199

Circulating metabolites and general cognitive ability and dementia: evidence from 11 cohort studies

van der Lee, S. J., Teunissen, C. E., Pool, R., Shipley, M. J., Teumer, A., Chouraki, V., Melo van Lent, D., Tynkkynen, J., Fischer, K., Hernesniemi, J., et al. (2018) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchMetabolomics and Mass Spectrometry Studies

Cited by 197

APOE-related risk of mild cognitive impairment and dementia for prevention trials: An analysis of four cohorts

Qian, J., Wolters, F. J., Beiser, A., Haan, M., Ikram, M. A., Karlawish, J., Langbaum, J. B., Neuhaus, J. M., Reiman, E. M., Roberts, J. S., et al. (2017) · PLOS Medicine

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 169

Impact of physical activity on the association of overweight and obesity with cardiovascular disease: The Rotterdam Study

Koolhaas, C. M., Dhana, K., Schoufour, J. D., Ikram, M. A., Kavousi, M., & Franco, O. H. (2017) · European Journal of Preventive Cardiology

Physical Activity and HealthObesity, Physical Activity, Diet

Cited by 162

Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity

Joshi, P. K., Pirastu, N., Kentistou, K. A., Fischer, K., Hofer, E., Schraut, K. E., Clark, D. W., Nutile, T., Barnes, C. L. K., Timmers, P. R. H. J., et al. (2017) · Nature Communications

Genetic Associations and EpidemiologyGenetics, Aging, and Longevity in Model Organisms

Cited by 161

Total cerebral blood flow and total brain perfusion in the general population: the Rotterdam Scan Study

Vernooij, M. W., van der Lugt, A., Ikram, M. A., Wielopolski, P. A., Vrooman, H. A., Hofman, A., Krestin, G. P., & Breteler, M. M. (2008) · Journal of Cerebral Blood Flow & Metabolism

Advanced MRI Techniques and ApplicationsCerebrovascular and genetic disorders

Cited by 156