Ikram, M. Arfan

Rising rural body-mass index is the main driver of the global obesity epidemic in adults

NCD Risk Factor Collaboration (NCD-RisC), Bixby, H., Bentham, J., Zhou, B., Di Cesare, M., Paciorek, C. J., Bennett, J. E., Taddei, C., Stevens, G. A., Rodriguez-Martinez, A., et al. (2019) · Nature

Obesity, Physical Activity, DietIndigenous Health and Education

Cited by 735

Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

Mahajan, A., Spracklen, C. N., Zhang, W., Ng, M. C. Y., Petty, L. E., Kitajima, H., Yu, G. Z., Rüeger, S., Speidel, L., Kim, Y. J., et al. (2022) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 704

Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data

Holmes, M. V., Dale, C. E., Zuccolo, L., Silverwood, R. J., Guo, Y., Ye, Z., Prieto-Merino, D., Dehghan, A., Trompet, S., Wong, A., et al. (2014) · BMJ

Alcohol Consumption and Health EffectsGenetic Associations and Epidemiology

Cited by 669

Rare and low-frequency coding variants alter human adult height

Marouli, E., Graff, M., Medina-Gomez, C., Lo, K. S., Wood, A. R., Kjaer, T. R., Fine, R. S., Lu, Y., Schurmann, C., Highland, H. M., et al. (2017) · Nature

Genetic Associations and EpidemiologyGenetics and Physical Performance

Cited by 610

Genetic drivers of heterogeneity in type 2 diabetes pathophysiology

Suzuki, K., Hatzikotoulas, K., Southam, L., Taylor, H. J., Yin, X., Lorenz, K. M., Mandla, R., Huerta-Chagoya, A., Melloni, G. E. M., Kanoni, S., et al. (2024) · Nature

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 606

Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk

Study, T. L. C., Day, F. R., The InterAct Consortium, kConFab/AOCS Investigators, Endometrial Cancer Association Consortium, Ovarian Cancer Association Consortium, PRACTICAL consortium, Thompson, D. J., Helgason, H., Chasman, D. I., et al. (2017) · Nature Genetics

Hypothalamic control of reproductive hormonesGenetic Associations and Epidemiology

Cited by 587

Prevalence and Risk Factors of Cerebral Microbleeds: An Update of the Rotterdam Scan Study

Poels, M. M. F., Vernooij, M. W., Ikram, M. A., Hofman, A., Krestin, G. P., van der Lugt, A., & Breteler, M. M. B. (2010) · Stroke

Intracerebral and Subarachnoid Hemorrhage ResearchCerebrovascular and genetic disorders

Cited by 563

Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation

Min, J. L., Hemani, G., Hannon, E., Dekkers, K. F., Castillo-Fernandez, J., Luijk, R., Carnero-Montoro, E., Lawson, D. J., Burrows, K., Suderman, M., et al. (2021) · Nature Genetics

Epigenetics and DNA MethylationGenetic Associations and Epidemiology

Cited by 506

Genome-wide association meta-analysis of 78,308 individuals identifies new loci and genes influencing human intelligence

Sniekers, S., Stringer, S., Watanabe, K., Jansen, P. R., Coleman, J. R. I., Krapohl, E., Taskesen, E., Hammerschlag, A. R., Okbay, A., Zabaneh, D., et al. (2017) · Nature Genetics

Genetic Associations and EpidemiologyCognitive Abilities and Testing

Cited by 490

Twenty-seven-year time trends in dementia incidence in Europe and the United States: The Alzheimer Cohorts Consortium

Wolters, F. J., Chibnik, L. B., Waziry, R., Anderson, R., Berr, C., Beiser, A., Bis, J. C., Blacker, D., Bos, D., Brayne, C., et al. (2020) · Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 489

Genomewide Association Studies of Stroke

Ikram, M. A., Seshadri, S., Bis, J. C., Fornage, M., DeStefano, A. L., Aulchenko, Y. S., Debette, S., Lumley, T., Folsom, A. R., van den Herik, E. G., et al. (2009) · New England Journal of Medicine

Genetic Associations and EpidemiologyAcute Ischemic Stroke Management

Cited by 458

Quantifying prion disease penetrance using large population control cohorts

Minikel, E. V., Vallabh, S. M., Lek, M., Estrada, K., Samocha, K. E., Sathirapongsasuti, J. F., McLean, C. Y., Tung, J. Y., Yu, L. P. C., Gambetti, P., et al. (2016) · Science Translational Medicine

Prion Diseases and Protein MisfoldingGenomics and Rare Diseases

Cited by 442

A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease

The International Genomics of Alzheimer's Project, Huang, K.-L., Initiative, T. A. D. N., Marcora, E., Pimenova, A. A., Di Narzo, A. F., Kapoor, M., Jin, S. C., Harari, O., Bertelsen, S., et al. (2017) · Nature Neuroscience

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 423

Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories: a pooled analysis of 2181 population-based studies with 65 million participants

Rodriguez-Martinez, A., Zhou, B., Sophiea, M. K., Bentham, J., Paciorek, C. J., Iurilli, M. L., Carrillo-Larco, R. M., Bennett, J. E., Di Cesare, M., Taddei, C., et al. (2020) · The Lancet

Obesity, Physical Activity, DietHuman Health and Disease

Cited by 417

Genome-wide meta-analysis identifies new susceptibility loci for migraine

North American Brain Expression Consortium, Anttila, V., UK Brain Expression Consortium, the International Headache Genetics Consortium, Winsvold, B. S., Gormley, P., Kurth, T., Bettella, F., McMahon, G., Kallela, M., et al. (2013) · Nature Genetics

Migraine and Headache StudiesGenetic Associations and Epidemiology

Cited by 410

Is dementia incidence declining?: Trends in dementia incidence since 1990 in the Rotterdam Study

Schrijvers, E. M. C., Verhaaren, B. F. J., Koudstaal, P. J., Hofman, A., Ikram, M. A., & Breteler, M. M. B. (2012) · Neurology

Dementia and Cognitive Impairment ResearchNeurological Disease Mechanisms and Treatments

Cited by 408

Metabolomic profiles predict individual multidisease outcomes

Buergel, T., Steinfeldt, J., Ruyoga, G., Pietzner, M., Bizzarri, D., Vojinovic, D., Upmeier zu Belzen, J., Loock, L., Kittner, P., Christmann, L., et al. (2022) · Nature Medicine

Metabolomics and Mass Spectrometry StudiesHealth, Environment, Cognitive Aging

Cited by 406

Association of Cerebral Microbleeds With Cognitive Decline and Dementia

Akoudad, S., Wolters, F. J., Viswanathan, A., de Bruijn, R. F., van der Lugt, A., Hofman, A., Koudstaal, P. J., Ikram, M. A., & Vernooij, M. W. (2016) · JAMA Neurology

Dementia and Cognitive Impairment ResearchIntracerebral and Subarachnoid Hemorrhage Research

Cited by 403

10-year trajectories of depressive symptoms and risk of dementia: a population-based study

Mirza, S. S., Wolters, F. J., Swanson, S. A., Koudstaal, P. J., Hofman, A., Tiemeier, H., & Ikram, M. A. (2016) · The Lancet Psychiatry

Dementia and Cognitive Impairment ResearchMental Health Treatment and Access

Cited by 385

Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53 949)

Davies, G., Armstrong, N., Bis, J. C., Bressler, J., Chouraki, V, Giddaluru, S., Hofer, E., Ibrahim-Verbaas, C. A., Kirin, M., Lahti, J., et al. (2015) · Molecular Psychiatry

Genetic Associations and EpidemiologyCognitive Abilities and Testing

Cited by 384

Cerebral microbleeds are associated with worse cognitive function: The Rotterdam Scan Study

Poels, M. M. F., Ikram, M. A., van der Lugt, A., Hofman, A., Niessen, W. J., Krestin, G. P., Breteler, M. M. B., & Vernooij, M. W. (2012) · Neurology

Cerebrovascular and genetic disordersDementia and Cognitive Impairment Research

Cited by 378

A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals

Deelen, J., Kettunen, J., Fischer, K., van der Spek, A., Trompet, S., Kastenmüller, G., Boyd, A., Zierer, J., van den Akker, E. B., Ala-Korpela, M., et al. (2019) · Nature Communications

Metabolomics and Mass Spectrometry StudiesHealth, Environment, Cognitive Aging

Cited by 362

White Matter Microstructural Integrity and Cognitive Function in a General Elderly Population

Vernooij, M. W., Ikram, M. A., Vrooman, H. A., Wielopolski, P. A., Krestin, G. P., Hofman, A., Niessen, W. J., Van der Lugt, A., & Breteler, M. M. B. (2009) · Archives of General Psychiatry

Advanced Neuroimaging Techniques and ApplicationsDementia and Cognitive Impairment Research

Cited by 335

A Genome-Wide Association Study Identifies Five Loci Influencing Facial Morphology in Europeans

Liu, F., van der Lijn, F., Schurmann, C., Zhu, G., Chakravarty, M. M., Hysi, P. G., Wollstein, A., Lao, O., de Bruijne, M., Ikram, M. A., et al. (2012) · PLoS Genetics

Genetic Associations and EpidemiologyMorphological variations and asymmetry

Cited by 326