Rhodes, Christopher J.

Key enzyme in leptin-induced anorexia

Niswender, K. D., Morton, G. J., Stearns, W. H., Rhodes, C. J., Myers, M. G., & Schwartz, M. W. (2001) · Nature

Regulation of Appetite and ObesityHypothalamic control of reproductive hormones

Cited by 585

Whole-genome sequencing of patients with rare diseases in a national health system

Turro, E., Astle, W. J., Megy, K., Gräf, S., Greene, D., Shamardina, O., Allen, H. L., Sanchis-Juan, A., Frontini, M., Thys, C., et al. (2020) · Nature

Genomics and Rare DiseasesGenetic Associations and Epidemiology

Cited by 554

β-Cell Failure in Type 2 Diabetes: Postulated Mechanisms and Prospects for Prevention and Treatment

Halban, P. A., Polonsky, K. S., Bowden, D. W., Hawkins, M. A., Ling, C., Mather, K. J., Powers, A. C., Rhodes, C. J., Sussel, L., & Weir, G. C. (2014) · Diabetes Care

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 460

Leptin Acts via Leptin Receptor-Expressing Lateral Hypothalamic Neurons to Modulate the Mesolimbic Dopamine System and Suppress Feeding

Leinninger, G. M., Jo, Y.-H., Leshan, R. L., Louis, G. W., Yang, H., Barrera, J. G., Wilson, H., Opland, D. M., Faouzi, M. A., Gong, Y., et al. (2009) · Cell Metabolism

Regulation of Appetite and ObesityNeurotransmitter Receptor Influence on Behavior

Cited by 412

Glucose or diabetes activates p38 mitogen-activated protein kinase via different pathways

Igarashi, M., Wakasaki, H., Takahara, N., Ishii, H., Jiang, Z.-Y., Yamauchi, T., Kuboki, K., Meier, M., Rhodes, C. J., & King, G. L. (1999) · Journal of Clinical Investigation

Protein Kinase Regulation and GTPase SignalingAdvanced Glycation End Products research

Cited by 386

Identification of rare sequence variation underlying heritable pulmonary arterial hypertension

Gräf, S., Haimel, M., Bleda, M., Hadinnapola, C., Southgate, L., Li, W., Hodgson, J., Liu, B., Salmon, R. M., Southwood, M., et al. (2018) · Nature Communications

Pulmonary Hypertension Research and TreatmentsVascular Anomalies and Treatments

Cited by 380

Formation of a human β-cell population within pancreatic islets is set early in life

Gregg, B. E., Moore, P. C., Demozay, D., Hall, B. A., Li, M., Husain, A., Wright, A. J., Atkinson, M. A., & Rhodes, C. J. (2012) · The Journal of Clinical Endocrinology & Metabolism

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 344

Leptin regulates insulin sensitivity via phosphatidylinositol-3-OH kinase signaling in mediobasal hypothalamic neurons

Morton, G. J., Gelling, R. W., Niswender, K. D., Morrison, C. D., Rhodes, C. J., & Schwartz, M. W. (2005) · Cell Metabolism

Regulation of Appetite and ObesityAdipokines, Inflammation, and Metabolic Diseases

Cited by 292

How Does Type 1 Diabetes Develop?

Atkinson, M. A., Bluestone, J. A., Eisenbarth, G. S., Hebrok, M., Herold, K. C., Accili, D., Pietropaolo, M., Arvan, P. R., Von Herrath, M., Markel, D. S., et al. (2011) · Diabetes

Diabetes and associated disordersPancreatic function and diabetes

Cited by 232

Insulin Regulates Glucagon-Like Peptide-1 Secretion from the Enteroendocrine L Cell

Lim, G. E., Huang, G. J., Flora, N., LeRoith, D., Rhodes, C. J., & Brubaker, P. L. (2009) · Endocrinology

Diabetes Treatment and ManagementPancreatic function and diabetes

Cited by 200

Insulin action in the brain contributes to glucose lowering during insulin treatment of diabetes

Gelling, R. W., Morton, G. J., Morrison, C. D., Niswender, K. D., Myers, M. G., Rhodes, C. J., & Schwartz, M. W. (2006) · Cell Metabolism

Regulation of Appetite and ObesityPancreatic function and diabetes

Cited by 169

Hypothalamic Leptin Signaling Regulates Hepatic Insulin Sensitivity via a Neurocircuit Involving the Vagus Nerve

German, J., Kim, F., Schwartz, G. J., Havel, P. J., Rhodes, C. J., Schwartz, M. W., & Morton, G. J. (2009) · Endocrinology

Regulation of Appetite and ObesityPancreatic function and diabetes

Cited by 164

Arcuate Nucleus-Specific Leptin Receptor Gene Therapy Attenuates the Obesity Phenotype of Koletsky (fak/fak) Rats

Morton, G. J., Niswender, K. D., Rhodes, C. J., Myers, M. G., Blevins, J. E., Baskin, D. G., & Schwartz, M. W. (2003) · Endocrinology

Regulation of Appetite and ObesityHypothalamic control of reproductive hormones

Cited by 158

Ventral Tegmental Area Leptin Receptor Neurons Specifically Project to and Regulate Cocaine- and Amphetamine-Regulated Transcript Neurons of the Extended Central Amygdala

Leshan, R. L., Opland, D. M., Louis, G. W., Leinninger, G. M., Patterson, C. M., Rhodes, C. J., Münzberg, H., & Myers, M. G. (2010) · The Journal of Neuroscience

Regulation of Appetite and ObesityNeurotransmitter Receptor Influence on Behavior

Cited by 127

Signal Transducer and Activator of Transcription 5 Activation Is Sufficient to Drive Transcriptional Induction of Cyclin D2 Gene and Proliferation of Rat Pancreatic β-Cells

Friedrichsen, B. N., Richter, H. E., Hansen, J. A., Rhodes, C. J., Nielsen, J. H., Billestrup, N., & Møldrup, A. (2003) · Molecular Endocrinology

Pancreatic function and diabetesCytokine Signaling Pathways and Interactions

Cited by 93

Fluorescent Cargo Proteins in Pancreatic β-Cells: Design Determines Secretion Kinetics at Exocytosis

Michael, D. J., Geng, X., Cawley, N. X., Loh, Y. P., Rhodes, C. J., Drain, P., & Chow, R. H. (2004) · Biophysical Journal

Cellular transport and secretionPancreatic function and diabetes

Cited by 66

De Novo Truncating Mutations in WASF1 Cause Intellectual Disability with Seizures

Ito, Y., Carss, K. J., Duarte, S. T., Hartley, T., Keren, B., Kurian, M. A., Marey, I., Charles, P., Mendonça, C., Nava, C., et al. (2018) · The American Journal of Human Genetics

Genetics and Neurodevelopmental DisordersGenomics and Rare Diseases

Cited by 41