Thomas, Russell S.

Integration of Dosimetry, Exposure, and High-Throughput Screening Data in Chemical Toxicity Assessment

Wetmore, B. A., Wambaugh, J. F., Ferguson, S. S., Sochaski, M. A., Rotroff, D. M., Freeman, K., Clewell, H. J., Dix, D. J., Andersen, M. E., Houck, K. A., et al. (2012) · Toxicological Sciences

Animal testing and alternativesCarcinogens and Genotoxicity Assessment

Cited by 415

Portosystemic shunting and persistent fetal vascular structures in aryl hydrocarbon receptor-deficient mice

Lahvis, G. P., Lindell, S. L., Thomas, R. S., McCuskey, R. S., Murphy, C., Glover, E., Bentz, M., Southard, J., & Bradfield, C. A. (2000) · Proceedings of the National Academy of Sciences

Liver physiology and pathologyCardiovascular Conditions and Treatments

Cited by 377

The Tox21 10K Compound Library: Collaborative Chemistry Advancing Toxicology

Richard, A. M., Huang, R., Waidyanatha, S., Shinn, P., Collins, B. J., Thillainadarajah, I., Grulke, C. M., Williams, A. J., Lougee, R. R., Judson, R. S., et al. (2021) · Chemical Research in Toxicology

Computational Drug Discovery MethodsEnvironmental Toxicology and Ecotoxicology

Cited by 323

Screening Chemicals for Estrogen Receptor Bioactivity Using a Computational Model

Browne, P., Judson, R. S., Casey, W. M., Kleinstreuer, N. C., & Thomas, R. S. (2015) · Environmental Science & Technology

Effects and risks of endocrine disrupting chemicalsEstrogen and related hormone effects

Cited by 276

Editor's Highlight: Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space

Judson, R., Houck, K., Martin, M., Richard, A. M., Knudsen, T. B., Shah, I., Little, S., Wambaugh, J., Woodrow Setzer, R., Kothya, P., et al. (2016) · Toxicological Sciences

Animal testing and alternativesEnvironmental Toxicology and Ecotoxicology

Cited by 232

The US Federal Tox21 Program: A strategic and operational plan for continued leadership

Thomas, R. (2018) · ALTEX

Animal testing and alternativesImmunotoxicology and immune responses

Cited by 229

IVT-seq reveals extreme bias in RNA sequencing

Lahens, N. F., Kavakli, I. H., Zhang, R., Hayer, K., Black, M. B., Dueck, H., Pizarro, A., Kim, J., Irizarry, R., Thomas, R. S., et al. (2014) · Genome Biology

Genomics and Phylogenetic StudiesSingle-cell and spatial transcriptomics

Cited by 158

A Chemical Category-Based Prioritization Approach for Selecting 75 Per- and Polyfluoroalkyl Substances (PFAS) for Tiered Toxicity and Toxicokinetic Testing

Patlewicz, G., Richard, A. M., Williams, A. J., Grulke, C. M., Sams, R., Lambert, J., Noyes, P. D., DeVito, M. J., Hines, R. N., Strynar, M., et al. (2019) · Environmental Health Perspectives

Per- and polyfluoroalkyl substances researchToxic Organic Pollutants Impact

Cited by 128

Progress towards an OECD reporting framework for transcriptomics and metabolomics in regulatory toxicology

Harrill, J. A., Viant, M. R., Yauk, C. L., Sachana, M., Gant, T. W., Auerbach, S. S., Beger, R. D., Bouhifd, M., O'Brien, J., Burgoon, L., et al. (2021) · Regulatory Toxicology and Pharmacology

Carcinogens and Genotoxicity AssessmentAnimal testing and alternatives

Cited by 105

Considerations for strategic use of high-throughput transcriptomics chemical screening data in regulatory decisions

Harrill, J., Shah, I., Setzer, R. W., Haggard, D., Auerbach, S., Judson, R., & Thomas, R. S. (2019) · Current Opinion in Toxicology

Animal testing and alternativesCarcinogens and Genotoxicity Assessment

Cited by 101

Knockout of the aryl hydrocarbon receptor results in distinct hepatic and renal phenotypes in rats and mice

Harrill, J. A., Hukkanen, R. R., Lawson, M., Martin, G., Gilger, B., Soldatow, V., LeCluyse, E. L., Budinsky, R. A., Rowlands, J. C., & Thomas, R. S. (2013) · Toxicology and Applied Pharmacology

Toxic Organic Pollutants ImpactPharmacogenetics and Drug Metabolism

Cited by 83