Manrai, Arjun K.

Scientific discovery in the age of artificial intelligence.

Wang, H., Fu, T., Du, Y., Gao, W., Huang, K., Liu, Z., Chandak, P., Liu, S., Van Katwyk, P., Deac, A., et al. (2023) · Nature

Artificial Intelligence ApplicationsMachine Learning in Materials Science

Cited by 1,823

Genetic Misdiagnoses and the Potential for Health Disparities

Manrai, A. K., Funke, B. H., Rehm, H. L., Olesen, M. S., Maron, B. A., Szolovits, P., Margulies, D. M., Loscalzo, J., & Kohane, I. S. (2016) · New England Journal of Medicine

Genomics and Rare DiseasesCardiomyopathy and Myosin Studies

Cited by 808

CEAS: cis-regulatory element annotation system

Shin, H., Liu, T., Manrai, A. K., & Liu, X. S. (2009) · Bioinformatics

Genomics and Chromatin DynamicsGenomics and Phylogenetic Studies

Cited by 461

Challenges to the Reproducibility of Machine Learning Models in Health Care

Beam, A. L., Manrai, A. K., & Ghassemi, M. (2020) · JAMA

Artificial Intelligence in Healthcare and EducationMachine Learning in Healthcare

Cited by 366

Artificial Intelligence in Medicine

Beam, A. L., Drazen, J. M., Kohane, I. S., Leong, T.-Y., Manrai, A. K., & Rubin, E. J. (2023) · New England Journal of Medicine

Artificial Intelligence in Healthcare and EducationArtificial Intelligence in Healthcare

Cited by 303

Medical Artificial Intelligence and Human Values

Yu, K.-H., Healey, E., Leong, T.-Y., Kohane, I. S., & Manrai, A. K. (2024) · New England Journal of Medicine

Artificial Intelligence in Healthcare and EducationEthics and Social Impacts of AI

Cited by 149

In Search of a Better Equation — Performance and Equity in Estimates of Kidney Function

Diao, J. A., Inker, L. A., Levey, A. S., Tighiouart, H., Powe, N. R., & Manrai, A. K. (2021) · New England Journal of Medicine

Chronic Kidney Disease and DiabetesRace, Genetics, and Society

Cited by 115

In the Era of Precision Medicine and Big Data, Who Is Normal?

Manrai, A. K., Patel, C. J., & Ioannidis, J. P. A. (2018) · JAMA

Medicine, History, and PhilosophyArtificial Intelligence in Healthcare and Education

Cited by 98

Foundational Considerations for Artificial Intelligence Using Ophthalmic Images

Abràmoff, M. D., Cunningham, B., Patel, B., Eydelman, M. B., Leng, T., Sakamoto, T., Blodi, B., Grenon, S. M., Wolf, R. M., Manrai, A. K., et al. (2022) · Ophthalmology

Artificial Intelligence in Healthcare and EducationEthics and Social Impacts of AI

Cited by 96

Association of Sex With Recurrence of Autism Spectrum Disorder Among Siblings

Palmer, N., Beam, A., Agniel, D., Eran, A., Manrai, A., Spettell, C., Steinberg, G., Mandl, K., Fox, K., Nelson, S. F., et al. (2017) · JAMA Pediatrics

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

Cited by 89

Medicine’s Uncomfortable Relationship With Math: Calculating Positive Predictive Value

Manrai, A. K., Bhatia, G., Strymish, J., Kohane, I. S., & Jain, S. H. (2014) · JAMA Internal Medicine

Palliative Care and End-of-Life IssuesPalliative and Oncologic Care

Cited by 74

Scalability and cost-effectiveness analysis of whole genome-wide association studies on Google Cloud Platform and Amazon Web Services

Krissaane, I., De Niz, C., Gutiérrez-Sacristán, A., Korodi, G., Ede, N., Kumar, R., Lyons, J., Manrai, A., Patel, C., Kohane, I., et al. (2020) · Journal of the American Medical Informatics Association

Cloud Computing and Resource ManagementScientific Computing and Data Management

Cited by 28

Discordance between a deep learning model and clinical-grade variant pathogenicity classification in a rare disease cohort

Kong, S. W., Lee, I.-H., Collen, L. V., Field, M., Manrai, A. K., Snapper, S. B., & Mandl, K. D. (2025) · npj Genomic Medicine

Genomics and Rare DiseasesGenetic Associations and Epidemiology

Cited by 18

Discordance between a deep learning model and clinical-grade variant pathogenicity classification in a rare disease cohort

Kong, S. W., Lee, I.-H., Collen, L. V., Manrai, A. K., Snapper, S. B., & Mandl, K. D. (2024) · npj Genomic Medicine

Genomics and Rare DiseasesGenetic Associations and Epidemiology

Cited by 18

Accelerating Science with Human+AI Review

Manrai, A. K., Ouyang, D., Hogan, J. W., & Kohane, I. S. (2025) · NEJM AI

Artificial Intelligence in Healthcare and EducationArtificial Intelligence Applications

Cited by 17