Thomas, Douglas D.

The chemical biology of nitric oxide: Implications in cellular signaling

Thomas, D. D., Ridnour, L. A., Isenberg, J. S., Flores-Santana, W., Switzer, C. H., Donzelli, S., Hussain, P., Vecoli, C., Paolocci, N., Ambs, S., et al. (2008) · Free Radical Biology and Medicine

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 975

The biological lifetime of nitric oxide: Implications for the perivascular dynamics of NO and O 2

Thomas, D. D., Liu, X., Kantrow, S. P., & Lancaster, J. R. (2001) · Proceedings of the National Academy of Sciences

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 760

Accelerated reaction of nitric oxide with O 2 within the hydrophobic interior of biological membranes

Liu, X., Miller, M. J. S., Joshi, M. S., Thomas, D. D., & Lancaster, J. R. (1998) · Proceedings of the National Academy of Sciences

Nitric Oxide and Endothelin EffectsAntioxidant Activity and Oxidative Stress

Cited by 602

The chemistry of nitrosative stress induced by nitric oxide and reactive nitrogen oxide species. Putting perspective on stressful biological situations

Ridnour, L. A., Thomas, D. D., Mancardi, D., Espey, M. G., Miranda, K. M., Paolocci, N., Feelisch, M., Fukuto, J., & Wink, D. A. (2004) · Biological Chemistry

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 312

Hypoxic inducible factor 1α, extracellular signal-regulated kinase, and p53 are regulated by distinct threshold concentrations of nitric oxide

Thomas, D. D., Espey, M. G., Ridnour, L. A., Hofseth, L. J., Mancardi, D., Harris, C. C., & Wink, D. A. (2004) · Proceedings of the National Academy of Sciences

Cancer, Hypoxia, and MetabolismNitric Oxide and Endothelin Effects

Cited by 289

A biochemical rationale for the discrete behavior of nitroxyl and nitric oxide in the cardiovascular system

Miranda, K. M., Paolocci, N., Katori, T., Thomas, D. D., Ford, E., Bartberger, M. D., Espey, M. G., Kass, D. A., Feelisch, M., Fukuto, J. M., et al. (2003) · Proceedings of the National Academy of Sciences

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 283

The biphasic nature of nitric oxide responses in tumor biology

Ridnour, L. A., Thomas, D. D., Donzelli, S., Espey, M. G., Roberts, D. D., Wink, D. A., & Isenberg, J. S. (2006) · Antioxidants & Redox Signaling

Nitric Oxide and Endothelin EffectsAngiogenesis and VEGF in Cancer

Cited by 247

Nitric oxide regulates matrix metalloproteinase-9 activity by guanylyl-cyclase-dependent and -independent pathways

Ridnour, L. A., Windhausen, A. N., Isenberg, J. S., Yeung, N., Thomas, D. D., Vitek, M. P., Roberts, D. D., & Wink, D. A. (2007) · Proceedings of the National Academy of Sciences

Protease and Inhibitor MechanismsNitric Oxide and Endothelin Effects

Cited by 219

Dinitrosyliron complexes are the most abundant nitric oxide-derived cellular adduct: biological parameters of assembly and disappearance

Hickok, J. R., Sahni, S., Shen, H., Arvind, A., Antoniou, C., Fung, L. W. M., & Thomas, D. D. (2011) · Free Radical Biology and Medicine

Nitric Oxide and Endothelin EffectsHemoglobin structure and function

Cited by 155

Signaling and stress: The redox landscape in NOS2 biology

Thomas, D. D., Heinecke, J. L., Ridnour, L. A., Cheng, R. Y., Kesarwala, A. H., Switzer, C. H., McVicar, D. W., Roberts, D. D., Glynn, S., Fukuto, J. M., et al. (2015) · Free Radical Biology and Medicine

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 150

Superoxide fluxes limit nitric oxide-induced signaling

Thomas, D. D., Ridnour, L. A., Espey, M. G., Donzelli, S., Ambs, S., Hussain, S. P., Harris, C. C., DeGraff, W., Roberts, D. D., Mitchell, J. B., et al. (2006) · Journal of Biological Chemistry

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 121

Discriminating formation of HNO from other reactive nitrogen oxide species

Donzelli, S., Espey, M. G., Thomas, D. D., Mancardi, D., Tocchetti, C. G., Ridnour, L. A., Paolocci, N., King, S. B., Miranda, K. M., Lazzarino, G., et al. (2006) · Free Radical Biology and Medicine

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 112

Heme Proteins and Nitric Oxide (NO): The Neglected, Eloquent Chemistry in NO Redox Signaling and Regulation

Thomas, D. D., Miranda, K. M., Colton, C. A., Citrin, D., Espey, M. G., & Wink, D. A. (2003) · Antioxidants & Redox Signaling

Hemoglobin structure and functionMetal-Catalyzed Oxygenation Mechanisms

Cited by 89

Nitric Oxide Suppresses Tumor Cell Migration through N-Myc Downstream-regulated Gene-1 (NDRG1) Expression

Hickok, J. R., Sahni, S., Mikhed, Y., Bonini, M. G., & Thomas, D. D. (2011) · Journal of Biological Chemistry

Mechanisms of cancer metastasisNitric Oxide and Endothelin Effects

Cited by 80

Guide for the use of nitric oxide (NO) donors as probes of the chemistry of NO and related redox species in biological systems

Thomas, D. D., Miranda, K. M., Graham Espey, M., Citrin, D., Jourd'heuil, D., Paolocci, N., Hewett, S. J., Colton, C. A., Grisham, M. B., Feelisch, M., et al. (2002) · Methods in Enzymology

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 76

Comparing the chemical biology of NO and HNO

Flores-Santana, W., Switzer, C., Ridnour, L. A., Basudhar, D., Mancardi, D., Donzelli, S., Thomas, D. D., Miranda, K. M., Fukuto, J. M., & Wink, D. A. (2009) · Archives of Pharmacal Research

Nitric Oxide and Endothelin EffectsHemoglobin structure and function

Cited by 50

Oxygen dependence of nitric oxide-mediated signaling

Hickok, J. R., Vasudevan, D., Jablonski, K., & Thomas, D. D. (2013) · Redox Biology

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 47

Is S -Nitrosocysteine a True Surrogate for Nitric Oxide?

Hickok, J. R., Vasudevan, D., Thatcher, G. R. J., & Thomas, D. D. (2012) · Antioxidants & Redox Signaling

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 42