Setchell, Kenneth D.R.

The clinical importance of the metabolite equol-a clue to the effectiveness of soy and its isoflavones

Setchell, K. D. R., Brown, N. M., & Lydeking-Olsen, E. (2002) · The Journal of Nutrition

Phytoestrogen effects and researchPhytochemicals and Antioxidant Activities

Cited by 1,209

Bile acid biosynthesis

Russell, D. W., & Setchell, K. D. R. (1992) · Biochemistry

Cholesterol and Lipid MetabolismDrug Transport and Resistance Mechanisms

Cited by 819

Equol: History, Chemistry, and Formation

Setchell, K. D. R., & Clerici, C. (2010) · The Journal of Nutrition

Phytoestrogen effects and researchPhytochemicals and Antioxidant Activities

Cited by 519

S-Equol, a potent ligand for estrogen receptor β, is the exclusive enantiomeric form of the soy isoflavone metabolite produced by human intestinal bacterial flora1–4,

Setchell, K. D., Clerici, C., Lephart, E. D., Cole, S. J., Heenan, C., Castellani, D., Wolfe, B. E., Nechemias-Zimmer, L., Brown, N. M., Lund, T. D., et al. (2005) · The American Journal of Clinical Nutrition

Phytoestrogen effects and researchPhytochemicals and Antioxidant Activities

Cited by 471

Identification of a new inborn error in bile acid synthesis: mutation of the oxysterol 7alpha-hydroxylase gene causes severe neonatal liver disease.

Setchell, K. D., Schwarz, M., O'Connell, N. C., Lund, E. G., Davis, D. L., Lathe, R., Thompson, H. R., Weslie Tyson, R., Sokol, R. J., & Russell, D. W. (1998) · Journal of Clinical Investigation

Metabolism and Genetic DisordersCholesterol and Lipid Metabolism

Cited by 375

Weight loss induced by Roux-en-Y gastric bypass but not laparoscopic adjustable gastric banding increases circulating bile acids

Kohli, R., Bradley, D., Setchell, K. D., Eagon, J. C., Abumrad, N., & Klein, S. (2013) · The Journal of Clinical Endocrinology & Metabolism

Bariatric Surgery and OutcomesMinimally Invasive Surgical Techniques

Cited by 265

Inhibition of ileal bile acid uptake protects against nonalcoholic fatty liver disease in high-fat diet–fed mice

Rao, A., Kosters, A., Mells, J. E., Zhang, W., Setchell, K. D. R., Amanso, A. M., Wynn, G. M., Xu, T., Keller, B. T., Yin, H., et al. (2016) · Science Translational Medicine

Liver Disease Diagnosis and TreatmentDrug Transport and Resistance Mechanisms

Cited by 211

Pharmacological inhibition of apical sodium-dependent bile acid transporter changes bile composition and blocks progression of sclerosing cholangitis in multidrug resistance 2 knockout mice

Miethke, A. G., Zhang, W., Simmons, J., Taylor, A. E., Shi, T., Shanmukhappa, S. K., Karns, R., White, S., Jegga, A. G., Lages, C. S., et al. (2016) · Hepatology

Drug Transport and Resistance MechanismsLiver Diseases and Immunity

Cited by 141

Alterations in xenobiotic metabolism in the long‐lived Little mice

Amador‐Noguez, D., Dean, A., Huang, W., Setchell, K., Moore, D., & Darlington, G. (2007) · Aging Cell

Drug Transport and Resistance MechanismsPharmacogenetics and Drug Metabolism

Cited by 134

Effect of soy protein-rich diet on renal function in young adults with insulin-dependent diabetes mellitus

Stephenson, T. J., Setchell, K. D. R., Kendall, C. W. C., Jenkins, D. J. A., Anderson, J. W., & Fanti, P. (2005) · Clinical Nephrology

Chronic Kidney Disease and DiabetesPhytoestrogen effects and research

Cited by 56