Westendorp, Rudi G. J.

Effect of thyroid substitution on hypercholesterolaemia in patients with subclinical hypothyroidism: a reanalysis of intervention studies

Tanis, B. C., Westendorp, R. G. J., & Smelt, A. H. M. (1996) · Clinical Endocrinology

Thyroid Disorders and TreatmentsThyroid and Parathyroid Surgery

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VDR gene variants associate with cognitive function and depressive symptoms in old age

Kuningas, M., Mooijaart, S. P., Jolles, J., Slagboom, P. E., Westendorp, R. G. J., & van Heemst, D. (2009) · Neurobiology of Aging

Vitamin D Research StudiesDementia and Cognitive Impairment Research

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What accounts for the wide variation in life span of genetically identical organisms reared in a constant environment?

Kirkwood, T. B. L., Feder, M., Finch, C. E., Franceschi, C., Globerson, A., Klingenberg, C. P., LaMarco, K., Omholt, S., & Westendorp, R. G. J. (2005) · Mechanisms of Ageing and Development

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

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Is depression in old age fatal only when people feel lonely?

Stek, M. L., Vinkers, D. J., Gussekloo, J., Beekman, A. T. F., van der Mast, R. C., & Westendorp, R. G. J. (2005) · American Journal of Psychiatry

Health disparities and outcomesAging, Health, and Disability

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Unraveling the directional link between adiposity and inflammation: A bidirectional Mendelian randomization approach

Welsh, P., Polisecki, E., Robertson, M., Jahn, S., Buckley, B. M., de Craen, A. J. M., Ford, I., Jukema, J. W., Macfarlane, P. W., Packard, C. J., et al. (2010) · The Journal of Clinical Endocrinology & Metabolism

Adipokines, Inflammation, and Metabolic DiseasesGenetic Associations and Epidemiology

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Familial Longevity Is Associated with Decreased Thyroid Function

Rozing, M. P., Houwing-Duistermaat, J. J., Slagboom, P. E., Beekman, M., Frölich, M., de Craen, A. J. M., Westendorp, R. G. J., & van Heemst, D. (2010) · The Journal of Clinical Endocrinology & Metabolism

Thyroid Disorders and TreatmentsGenetics, Aging, and Longevity in Model Organisms

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ApoE Plasma Levels and Risk of Cardiovascular Mortality in Old Age

Mooijaart, S. P., Berbée, J. F. P., van Heemst, D., Havekes, L. M., de Craen, A. J. M., Slagboom, P. E., Rensen, P. C. N., & Westendorp, R. G. J. (2006) · PLoS Medicine

Lipoproteins and Cardiovascular HealthParaoxonase enzyme and polymorphisms

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Impaired innate immunity predicts frailty in old age. The Leiden 85-plus study

van den Biggelaar, A. H. J., Huizinga, T. W. J., de Craen, A. J. M., Gussekloo, J., Heijmans, B. T., Frölich, M., & Westendorp, R. G. J. (2004) · Experimental Gerontology

Frailty in Older AdultsImmune Response and Inflammation

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Association Between Levothyroxine Treatment and Thyroid-Related Symptoms Among Adults Aged 80 Years and Older With Subclinical Hypothyroidism

Mooijaart, S. P., Du Puy, R. S., Stott, D. J., Kearney, P. M., Rodondi, N., Westendorp, R. G. J., den Elzen, W. P. J., Postmus, I., Poortvliet, R. K. E., van Heemst, D., et al. (2019) · JAMA

Thyroid Disorders and TreatmentsThyroid and Parathyroid Surgery

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Plasma lipoproteins and apolipoproteins as predictors of cardiovascular risk and treatment benefit in the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER)

Packard, C. J., Ford, I., Robertson, M., Shepherd, J., Blauw, G. J., Murphy, M. B., Bollen, E. L. E. M., Buckley, B. M., Cobbe, S. M., Gaw, A., et al. (2005) · Circulation

Lipoproteins and Cardiovascular HealthCholesterol and Lipid Metabolism

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Thyroid Hormone Signaling and Homeostasis During Aging

Bowers, J., Terrien, J., Clerget-Froidevaux, M. S., Gothié, J. D., Rozing, M. P., Westendorp, R. G. J., van Heemst, D., & Demeneix, B. A. (2013) · Endocrine Reviews

Genetics, Aging, and Longevity in Model OrganismsThyroid Disorders and Treatments

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Decline in total cerebral blood flow is linked with increase in periventricular but not deep white matter hyperintensities

ten Dam, V. H., van den Heuvel, D. M. J., de Craen, A. J. M., Bollen, E. L. E. M., Murray, H. M., Westendorp, R. G. J., Blauw, G. J., & van Buchem, M. A. (2007) · Radiology

Cerebrovascular and genetic disordersAdvanced MRI Techniques and Applications

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Effect of pravastatin on cerebral infarcts and white matter lesions

ten Dam, V. H., van den Heuvel, D. M. J., van Buchem, M. A., Westendorp, R. G. J., Bollen, E. L. E. M., Ford, I., de Craen, A. J. M., & Blauw, G. J. (2005) · Neurology

Lipoproteins and Cardiovascular HealthAcute Ischemic Stroke Management

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Lower proportion of naïve peripheral CD8+ T cells and an unopposed pro-inflammatory response to human Cytomegalovirus proteins in vitro are associated with longer survival in very elderly people

Derhovanessian, E., Maier, A. B., Hähnel, K., Zelba, H., de Craen, A. J. M., Roelofs, H., Slagboom, E. P., Westendorp, R. G. J., & Pawelec, G. (2013) · AGE

T-cell and B-cell ImmunologyCytomegalovirus and herpesvirus research

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Thyroid Function Within the Reference Range and the Risk of Stroke: An Individual Participant Data Analysis

Chaker, L., Baumgartner, C., den Elzen, W. P. J., Collet, T.-H., Ikram, M. A., Blum, M. R., Dehghan, A., Drechsler, C., Luben, R. N., Portegies, M. L. P., et al. (2016) · The Journal of Clinical Endocrinology & Metabolism

Thyroid Disorders and TreatmentsAcute Ischemic Stroke Management

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Cytomegalovirus infection and responsiveness to influenza vaccination in elderly residents of long-term care facilities

den Elzen, W. P. J., Vossen, A. C. M. T., Cools, H. J. M., Westendorp, R. G. J., Kroes, A. C. M., & Gussekloo, J. (2011) · Vaccine

Cytomegalovirus and herpesvirus researchInfluenza Virus Research Studies

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Long‐term exposure to air pollution and liver cancer incidence in six European cohorts

So, R., Chen, J., Mehta, A. J., Liu, S., Strak, M., Wolf, K., Hvidtfeldt, U. A., Rodopoulou, S., Stafoggia, M., Klompmaker, J. O., et al. (2021) · International Journal of Cancer

Air Quality and Health ImpactsEnvironmental Justice and Health Disparities

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Human longevity is characterised by high thyroid stimulating hormone secretion without altered energy metabolism

Jansen, S. W., Akintola, A. A., Roelfsema, F., van der Spoel, E., Cobbaert, C. M., Ballieux, B. E., Egri, P., Kvarta-Papp, Z., Gereben, B., Fekete, C., et al. (2015) · Scientific Reports

Thyroid Disorders and TreatmentsGenetics, Aging, and Longevity in Model Organisms

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Measuring Cognitive Function With Age: The Influence of Selection by Health and Survival

Euser, S. M., Schram, M. T., Hofman, A., Westendorp, R. G. J., & Breteler, M. M. B. (2008) · Epidemiology

Dementia and Cognitive Impairment ResearchStatistical Methods in Epidemiology

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Subclinical hypothyroidism and cognitive function in people over 60 years: a systematic review and meta-analysis

Akintola, A. A., Jansen, S. W., van Bodegom, D., van der Grond, J., Westendorp, R. G., de Craen, A. J. M., & van Heemst, D. (2015) · Frontiers in Aging Neuroscience

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Subclinical Thyroid Dysfunction and Cognitive Decline in Old Age

Wijsman, L. W., de Craen, A. J. M., Trompet, S., Gussekloo, J., Stott, D. J., Rodondi, N., Welsh, P., Jukema, J. W., Westendorp, R. G. J., & Mooijaart, S. P. (2013) · PLoS ONE

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PCSK9 SNP rs11591147 is associated with low cholesterol levels but not with cognitive performance or noncardiovascular clinical events in an elderly population

Postmus, I., Trompet, S., de Craen, A. J. M., Buckley, B. M., Ford, I., Stott, D. J., Sattar, N., Slagboom, P. E., Westendorp, R. G. J., & Jukema, J. W. (2013) · Journal of Lipid Research

Lipoproteins and Cardiovascular HealthCholesterol and Lipid Metabolism

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Men have a stronger monocyte-derived cytokine production response upon stimulation with the gram-negative stimulus lipopolysaccharide than women: a pooled analysis including 15 study populations

Beenakker, K. G. M., Westendorp, R. G. J., de Craen, A. J. M., Chen, S., Raz, Y., Ballieux, B. E. P. B., Nelissen, R. G. H. H., Later, A. F. L., Huizinga, T. W., Slagboom, P. E., et al. (2020) · Journal of Innate Immunity

Immune Response and InflammationSex and Gender in Healthcare

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The optimal healthy ranges of thyroid function defined by the risk of cardiovascular disease and mortality: systematic review and individual participant data meta-analysis

Xu, Y., Derakhshan, A., Hysaj, O., Wildisen, L., Ittermann, T., Pingitore, A., Abolhassani, N., Medici, M., Kiemeney, L. A. L. M., Riksen, N. P., et al. (2023) · The Lancet Diabetes & Endocrinology

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