Hutchinson, Mark R.

The “toll” of opioid-induced glial activation: improving the clinical efficacy of opioids by targeting glia

Watkins, L. R., Hutchinson, M. R., Rice, K. C., & Maier, S. F. (2009) · Trends in Pharmacological Sciences

Pain Mechanisms and TreatmentsPain Management and Opioid Use

Cited by 438

Opioid-induced glial activation: mechanisms of activation and implications for opioid analgesia, dependence, and reward

Hutchinson, M. R., Bland, S. T., Johnson, K. W., Rice, K. C., Maier, S. F., & Watkins, L. R. (2007) · The Scientific World JOURNAL

Pain Mechanisms and TreatmentsNeuropeptides and Animal Physiology

Cited by 359

A Chat(GPT) about the future of scientific publishing

Hill-Yardin, E. L., Hutchinson, M. R., Laycock, R., & Spencer, S. J. (2023) · Brain, Behavior, and Immunity

Artificial Intelligence in EducationArtificial Intelligence in Healthcare and Education

Cited by 270

Early-life experience decreases drug-induced reinstatement of morphine CPP in adulthood via microglial-specific epigenetic programming of anti-inflammatory IL-10 expression

Schwarz, J. M., Hutchinson, M. R., & Bilbo, S. D. (2011) · The Journal of Neuroscience

Neuroinflammation and Neurodegeneration MechanismsNeurotransmitter Receptor Influence on Behavior

Cited by 203

Implications of central immune signaling caused by drugs of abuse: Mechanisms, mediators and new therapeutic approaches for prediction and treatment of drug dependence

Coller, J. K., & Hutchinson, M. R. (2012) · Pharmacology & Therapeutics

Neuroinflammation and Neurodegeneration MechanismsNeurotransmitter Receptor Influence on Behavior

Cited by 186

“Listening” and “talking” to neurons: implications of immune activation for pain control and increasing the efficacy of opioids

Watkins, L. R., Hutchinson, M. R., Milligan, E. D., & Maier, S. F. (2007) · Brain Research Reviews

Pain Mechanisms and TreatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 185

Naturally-diverse airborne environmental microbial exposures modulate the gut microbiome and may provide anxiolytic benefits in mice

Liddicoat, C., Sydnor, H., Cando-Dumancela, C., Dresken, R., Liu, J., Gellie, N. J. C., Mills, J. G., Young, J. M., Weyrich, L. S., Hutchinson, M. R., et al. (2020) · Science of The Total Environment

Gut microbiota and healthUrban Green Space and Health

Cited by 140

Nitroxidative signaling mechanisms in pathological pain

Grace, P. M., Gaudet, A. D., Staikopoulos, V., Maier, S. F., Hutchinson, M. R., Salvemini, D., & Watkins, L. R. (2016) · Trends in Neurosciences

Pain Mechanisms and TreatmentsRedox biology and oxidative stress

Cited by 128

Effect of chronic delivery of the Toll-like receptor 4 antagonist (+)-naltrexone on incubation of heroin craving

Theberge, F. R., Li, X., Kambhampati, S., Pickens, C. L., St. Laurent, R., Bossert, J. M., Baumann, M. H., Hutchinson, M. R., Rice, K. C., Watkins, L. R., et al. (2013) · Biological Psychiatry

Neurotransmitter Receptor Influence on BehaviorNeuropeptides and Animal Physiology

Cited by 119

Toll-like receptor 4: innate immune regulator of neuroimmune and neuroendocrine interactions in stress and major depressive disorder

Liu, J., Buisman-Pijlman, F., & Hutchinson, M. R. (2014) · Frontiers in Neuroscience

Tryptophan and brain disordersStress Responses and Cortisol

Cited by 119

From the Bottom-Up: Chemotherapy and Gut-Brain Axis Dysregulation

Bajic, J. E., Johnston, I. N., Howarth, G. S., & Hutchinson, M. R. (2018) · Frontiers in Behavioral Neuroscience

Gastrointestinal motility and disordersCancer-related cognitive impairment studies

Cited by 100

B cells drive neuropathic pain–related behaviors in mice through IgG–Fc gamma receptor signaling

Lacagnina, M. J., Willcox, K. F., Boukelmoune, N., Bavencoffe, A., Sankaranarayanan, I., Barratt, D. T., Zuberi, Y. A., Dayani, D., Chavez, M. V., Lu, J. T., et al. (2024) · Science Translational Medicine

Pain Mechanisms and TreatmentsPain Management and Treatment

Cited by 60

Enhancement of antibody thermostability and affinity by computational design in the absence of antigen

Hutchinson, M., Ruffolo, J. A., Haskins, N., Iannotti, M., Vozza, G., Pham, T., Mehzabeen, N., Shandilya, H., Rickert, K., Croasdale-Wood, R., et al. (2023) · mAbs

Monoclonal and Polyclonal Antibodies Researchvaccines and immunoinformatics approaches

Cited by 22

Toward enhancement of antibody thermostability and affinity by computational design in the absence of antigen

Hutchinson, M., Ruffolo, J. A., Haskins, N., Iannotti, M., Vozza, G., Pham, T., Mehzabeen, N., Shandilya, H., Rickert, K., Croasdale-Wood, R., et al. (2024) · mAbs

Monoclonal and Polyclonal Antibodies Researchvaccines and immunoinformatics approaches

Cited by 22

The Relationship Between Androgens and Days per Month of Period Pain, Pelvic Pain, Headache, and TLR4 Responsiveness of Peripheral Blood Mononuclear Cells in Young Women with Dysmenorrhoea

Evans, S. F., Kwok, Y., Solterbeck, A., Pyragius, C., Hull, M. L., Hutchinson, M. R., & Rolan, P. (2021) · Journal of Pain Research

Menstrual Health and DisordersEndometriosis Research and Treatment

Cited by 21

Androgens, Endometriosis and Pain

Evans, S. F., Hull, M. L., Hutchinson, M. R., & Rolan, P. E. (2021) · Frontiers in Reproductive Health

Endometriosis Research and TreatmentMenstrual Health and Disorders

Cited by 14