Nitroxidative signaling mechanisms in pathological pain

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Cellular and Molecular Mechanisms of Pain

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Circulating mitochondrial DAMPs cause inflammatory responses to injury

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Activation and regulation of the inflammasomes

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Thioredoxin-interacting protein links oxidative stress to inflammasome activation

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Physiological Roles of Mitochondrial Reactive Oxygen Species

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Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis

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The Nrf2 regulatory network provides an interface between redox and intermediary metabolism

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Cellular mechanisms and physiological consequences of redox-dependent signalling

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TRPA1 Mediates the Inflammatory Actions of Environmental Irritants and Proalgesic Agents

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Reactive Oxygen Species Promote TNFα-Induced Death and Sustained JNK Activation by Inhibiting MAP Kinase Phosphatases

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TRP Channels and Pain

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Chronic pain in Australia: a prevalence study.

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Pathological pain and the neuroimmune interface

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Wallerian degeneration: gaining perspective on inflammatory events after peripheral nerve injury

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Nociceptor sensitization in pain pathogenesis

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Interactions between the immune and nervous systems in pain

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4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1

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Redox regulation of FoxO transcription factors

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Mitochondria: master regulators of danger signalling

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ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity

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Cutting Edge: Direct Interaction of TLR4 with NAD(P)H Oxidase 4 Isozyme Is Essential for Lipopolysaccharide-Induced Production of Reactive Oxygen Species and Activation of NF-κB

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Reactive Oxygen Species in the Regulation of Synaptic Plasticity and Memory

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TRPM2-mediated Ca2+ influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration

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The neuro-immune balance in neuropathic pain: Involvement of inflammatory immune cells, immune-like glial cells and cytokines

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Neurogenic neuroinflammation: inflammatory CNS reactions in response to neuronal activity

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Fatty Acids Modulate Toll-like Receptor 4 Activation through Regulation of Receptor Dimerization and Recruitment into Lipid Rafts in a Reactive Oxygen Species-dependent Manner

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P2X7 Mediates Superoxide Production in Primary Microglia and Is Up-regulated in a Transgenic Mouse Model of Alzheimer's Disease

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Beneficial effects of moderate exercise on mice aging: survival, behavior, oxidative stress, and mitochondrial electron transfer

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Biological and physiological role of reactive oxygen species - the good, the bad and the ugly

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Exploring the Neuroimmunopharmacology of Opioids: An Integrative Review of Mechanisms of Central Immune Signaling and Their Implications for Opioid Analgesia

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NF-κB Regulates Phagocytic NADPH Oxidase by Inducing the Expression of gp91

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A Newly Identified Role for Superoxide in Inflammatory Pain

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TRPM2 links oxidative stress to NLRP3 inflammasome activation

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Morphine paradoxically prolongs neuropathic pain in rats by amplifying spinal NLRP3 inflammasome activation

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Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity

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Accumulation of Free ADP-ribose from Mitochondria Mediates Oxidative Stress-induced Gating of TRPM2 Cation Channels

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Carbon monoxide differentially inhibits TLR signaling pathways by regulating ROS-induced trafficking of TLRs to lipid rafts

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Pain and analgesia: The dual effect of nitric oxide in the nociceptive system

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Roles of Reactive Oxygen and Nitrogen Species in Pain

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Fluorescent Probe HKSOX-1 for Imaging and Detection of Endogenous Superoxide in Live Cells and In Vivo

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New Insights on <i>NOX</i> Enzymes in the Central Nervous System

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Sod mimetics are coming of age

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Reactive oxygen species contribute to neuropathic pain by reducing spinal GABA release

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NADPH oxidase 2-derived reactive oxygen species in spinal cord microglia contribute to peripheral nerve injury-induced neuropathic pain

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Heme Oxygenase-1 Couples Activation of Mitochondrial Biogenesis to Anti-inflammatory Cytokine Expression

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Alleviating Suffering 101 — Pain Relief in the United States

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Intrathecal bone marrow stromal cells inhibit neuropathic pain via TGF-β secretion

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Caspase signalling in neuropathic and inflammatory pain in the rat

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TRPM2 Contributes to Inflammatory and Neuropathic Pain through the Aggravation of Pronociceptive Inflammatory Responses in Mice

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Animal models of chronic pain: Advances and challenges for clinical translation

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Role of oxidative stress in pathophysiology of peripheral neuropathy and modulation by N‐acetyl‐ l ‐cysteine in rats

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Mitotoxicity in distal symmetrical sensory peripheral neuropathies

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A Rationally Designed Upconversion Nanoprobe for in Vivo Detection of Hydroxyl Radical

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Nrf2 and NF-κB Modulation by Sulforaphane Counteracts Multiple Manifestations of Diabetic Neuropathy in Rats and High Glucose-Induced Changes

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Novel Therapeutic Strategy to Prevent Chemotherapy-Induced Persistent Sensory Neuropathy By TRPA1 Blockade

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Nitrooleic Acid, an Endogenous Product of Nitrative Stress, Activates Nociceptive Sensory Nerves via the Direct Activation of TRPA1

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NADPH Oxidase 2 Interaction with TLR2 Is Required for Efficient Innate Immune Responses to Mycobacteria via Cathelicidin Expression

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Nox4 is a Novel Inducible Source of Reactive Oxygen Species in Monocytes and Macrophages and Mediates Oxidized Low Density Lipoprotein–Induced Macrophage Death

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Oxidative stress in the spinal cord is an important contributor in capsaicin-induced mechanical secondary hyperalgesia in mice

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Reactive Oxygen Species Mediate Low Back Pain by Upregulating Substance P in Intervertebral Disc Degeneration

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Spinal Reactive Oxygen Species and Oxidative Damage Mediate Chronic Pain in Lame Dairy Cows

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Nitroxidative Stress, Cell—Signaling Pathways, and Manganese Porphyrins: Therapeutic Potential in Neuropathic Pain

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A role for neuroimmune signaling in a rat model of Gulf War Illness-related pain

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Thymus algeriensis and Thymus fontanesii exert neuroprotective effect against chronic constriction injury-induced neuropathic pain in rats

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Towards a Comprehensive Theory of Non-Cancer Acute and Chronic Pain Management: The Critical Role of Reactive Oxygen and Nitrogen Species in Pain, and Opioid Dependence, Addiction, Hyperalgesia, and Tolerance

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Effects of vitamin D administration on nociception and spinal cord pro-oxidant and antioxidant markers in a rat model of neuropathic pain

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Artesunate Reduces Remifentanil-induced Hyperalgesia and Peroxiredoxin-3 Hyperacetylation via Modulating Spinal Metabotropic Glutamate Receptor 5 in Rats

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Acute effects of brief mindfulness intervention coupled with carbohydrate ingestion to re-energize soccer players: a randomized crossover trial.

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Mitochondrial bioenergetics, glial reactivity, and pain-related behavior can be restored by dichloroacetate treatment in rodent pain models

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Peroxynitrite Contributes to Behavioral Responses, Increased Trigeminal Excitability, and Changes in Mitochondrial Function in a Preclinical Model of Migraine

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The potential role of T-cell metabolism-related molecules in chronic neuropathic pain after nerve injury: a narrative review

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STZ causes depletion of immune cells in sciatic nerve and dorsal root ganglion in experimental diabetes

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Chemical Composition and Antioxidant, Antinociceptive, and Anti‐inflammatory Activities of Four Amazonian Byrsonima Species

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The Parkinson’s disease DJ-1 / PARK7 gene controls peripheral neuronal excitability and painful neuropathy

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Involvement of Oxidative Stress and Nutrition in the Anatomy of Orofacial Pain

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Site-specific drug release of monomethyl fumarate to treat oxidative stress disorders

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Regulation of Mitochondrial Function by Epac2 Contributes to Acute Inflammatory Hyperalgesia

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Autofluorescent imprint of chronic constriction nerve injury identified by deep learning

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7-Chloro-4-(Phenylselanyl) Quinoline Is a Novel Multitarget Therapy to Combat Peripheral Neuropathy and Comorbidities Induced by Paclitaxel in Mice

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TLR4 induced TRPM2 mediated neuropathic pain

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The ambiguity of opioids revealed by immunology is changing the knowledge and the therapeutic approach in cancer and non-cancer pain: A narrative review

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Pain in Hemophilia: Unexplored Role of Oxidative Stress

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Synthetic Secoisolariciresinol Diglucoside Attenuates Established Pain, Oxidative Stress and Neuroinflammation in a Rodent Model of Painful Radiculopathy

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Effects of NADPH Oxidase Isoform-2 (NOX2) Inhibition on Behavioral Responses and Neuroinflammation in a Mouse Model of Neuropathic Pain

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H2S Alleviates Neuropathic Pain in Mice by Nrf2 Signaling Pathway Activation

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Reactive Oxygen Species Induced Upregulation of TRPV1 in Dorsal Root Ganglia Results in Low Back Pain in Rats

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Disrupted circadian rhythms and opioid‐mediated adverse effects: Bidirectional relationship and putative mechanisms

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Pain and the immune system

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Review: What innovations in pain measurement and control might be possible if we could quantify the neuroimmune synapse?

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Diverse roles and modulations of IA in spinal cord pain circuits

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Reordering neuroimmune signaling to prevent and resolve chronic pain

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Peripheral nerve injury reduces macrophage efferocytosis to facilitate neuropathic pain

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18 kDa Translocator protein (TSPO) is upregulated in rat brain after peripheral nerve injury and downregulated by diroximel fumarate

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Global use of Ethnomedicinal Plants to Treat Toothache

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Investigation of the Antinociceptive Activity of the Hydroethanolic Extract of Junglas nigra Leaf by the Tail-Immersion and Formalin Pain Tests in Rats

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Glabridin Therapy Reduces Chronic Allodynia, Spinal Microgliosis, and Dendritic Spine Generation by Inhibiting Fractalkine-CX3CR1 Signaling in a Mouse Model of Tibial Fractures

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Aqueous leaf extract from Luehea divaricata Mart. Modulates oxidative stress markers in the spinal cord of rats with neuropathic pain

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Constriction of the buccal branch of the facial nerve produces unilateral craniofacial allodynia

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Peripheral Activation of Formyl Peptide Receptor 2/ALX by Electroacupuncture Alleviates Inflammatory Pain by Increasing Interleukin-10 Levels and Catalase Activity in Mice

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The importance of knowing you are sick: Nanoscale biophotonics for the ‘other’ brain

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Hsp90: Is There an Unknown Role in Pain Neurobiology

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Spine-Adjusting Instrument (Impulse®) Attenuates Nociception and Modulates Oxidative Stress Markers in the Spinal Cord and Sciatic Nerve of a Rat Model of Neuropathic Pain

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Development of a C6 Glioma Cell Model System to Assess Effects of Cathodic Passively Balanced Electrical Stimulation on Responses to Neurotransmitters: Implications for Modulation of Intracellular Nitric Oxide, Chloride, and Calcium Ions

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Association between oxidative stress and chronic orofacial pain and potential druggable targets: Evidence from a Mendelian randomization study

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Strength training attenuates neuropathic pain by Preventing dendritic Spine dysgenesis through Suppressing Rac1 and inflammation in experimental autoimmune encephalomyelitis

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Techniques and factors for reducing chronic neuropathic pain: A review

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Toward Specific Detection of Peroxynitrite─Intramolecular Cyclization of Boronobenzylated Pyridinium Probe in Chemical and Cellular Systems

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Trans-Chalcone Reduces Inflammation and Pain Triggered by Superoxide Anion: Neuronal and Non-Neuronal Mechanisms

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Cell senescence in chronic pain: An integrative perspective on cellular and neural mechanisms

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Reactive Oxygen Species and Nitrogen Species Differentially Regulate Neuronal Excitability in Rat Spinal Substantia Gelatinosa Neurons

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Superoxide signaling in pain is independent of nitric oxide signaling

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