Yang, Chengran

Genomic atlas of the proteome from brain, CSF and plasma prioritizes proteins implicated in neurological disorders

Yang, C., Farias, F. H. G., Ibanez, L., Suhy, A., Sadler, B., Fernandez, M. V., Wang, F., Bradley, J. L., Eiffert, B., Bahena, J. A., et al. (2021) · Nature Neuroscience

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 290

Proteogenomic analysis of human cerebrospinal fluid identifies neurologically relevant regulation and informs causal proteins for Alzheimer's disease

Cruchaga, C., Western, D., Timsina, J., Wang, L., Wang, C., Yang, C., Ali, M., Beric, A., Gorijala, P., Kohlfeld, P., et al. (2023) · Nature Genetics

Genetic Associations and EpidemiologyAlzheimer's disease research and treatments

Cited by 112

Proteogenomic analysis of human cerebrospinal fluid identifies neurologically relevant regulation and implicates causal proteins for Alzheimer’s disease

Western, D., Timsina, J., Wang, L., Wang, C., Yang, C., Phillips, B., Wang, Y., Liu, M., Ali, M., Beric, A., et al. (2024) · Nature Genetics

Genetic Associations and EpidemiologyAlzheimer's disease research and treatments

Cited by 111

The TMEM106B FTLD-protective variant, rs1990621, is also associated with increased neuronal proportion

Li, Z., Farias, F. H. G., Dube, U., Del-Aguila, J. L., Mihindukulasuriya, K. A., Fernandez, M. V., Ibanez, L., Budde, J. P., Wang, F., Lake, A. M., et al. (2020) · Acta Neuropathologica

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 85

Proteomics of brain, CSF, and plasma identifies molecular signatures for distinguishing sporadic and genetic Alzheimer’s disease

Sung, Y. J., Yang, C., Norton, J., Johnson, M., Fagan, A., Bateman, R. J., Perrin, R. J., Morris, J. C., Farlow, M. R., Chhatwal, J. P., et al. (2023) · Science Translational Medicine

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 84

MicroRNA Profiling Reveals Marker of Motor Neuron Disease in ALS Models

Hoye, M. L., Koval, E. D., Wegener, A. J., Hyman, T. S., Yang, C., O'Brien, D. R., Miller, R. L., Cole, T., Schoch, K. M., Shen, T., et al. (2017) · The Journal of Neuroscience

Amyotrophic Lateral Sclerosis ResearchMicroRNA in disease regulation

Cited by 82

Proteo-genomics of soluble TREM2 in cerebrospinal fluid provides novel insights and identifies novel modulators for Alzheimer’s disease

Wang, L., Nykänen, N.-P., Western, D., Gorijala, P., Timsina, J., Li, F., Wang, Z., Ali, M., Yang, C., Marquié, M., et al. (2023) · Molecular Neurodegeneration

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 59

Proteo-genomics of soluble TREM2 in cerebrospinal fluid provides novel insights and identifies novel modulators for Alzheimer’s disease

Wang, L., Nykänen, N.-P., Western, D., Gorijala, P., Timsina, J., Li, F., Wang, Z., Ali, M., Yang, C., Liu, M., et al. (2024) · Molecular Neurodegeneration

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 58

Mendelian randomization and genetic colocalization infer the effects of the multi-tissue proteome on 211 complex disease-related phenotypes

Yang, C., Fagan, A. M., Perrin, R. J., Rhinn, H., Harari, O., & Cruchaga, C. (2022) · Genome Medicine

Genetic Associations and EpidemiologyBioinformatics and Genomic Networks

Cited by 53

Proteome Wide Association Studies of LRRK2 variants identify novel causal and druggable for Parkinson’s disease

Phillips, B., Western, D., Wang, L., Timsina, J., Sun, Y., Gorijala, P., Yang, C., Do, A., Nykänen, N.-P., Alvarez, I., et al. (2023) · npj Parkinson s Disease

Parkinson's Disease Mechanisms and TreatmentsGenetic Associations and Epidemiology

Cited by 20

Proteomic clusters underlie heterogeneity in preclinical Alzheimer’s disease progression

Wisch, J. K., Butt, O. H., Gordon, B. A., Schindler, S. E., Fagan, A. M., Henson, R. L., Yang, C., Boerwinkle, A. H., Benzinger, T. L. S., Holtzman, D. M., et al. (2023) · Brain

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 11

A genetic and proteomic comparison of key AD biomarkers across tissues

Marsh, T. W., Western, D., Timsina, J., Gorijala, P., Yang, C., Pastor, P., Liu, M., Morris, J. C., Bateman, R. J., Schindler, S. E., et al. (2024) · Alzheimer's & Dementia

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 6

TOPMed imputed genomics enhances genomic atlas of the human proteome in brain, cerebrospinal fluid, and plasma

Yi, H., Yang, Q., Repaci, C., Lee, C. M., Heo, G., Timsina, J., Gorijala, P., Yang, C., Budde, J., Wang, L., et al. (2024) · Scientific Data

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 5

Proteogenomics in cerebrospinal fluid and plasma reveals new biological fingerprint of cerebral small vessel disease

Debette, S., Caro, I., Western, D., Namba, S., Sun, N., Kawaguchi, S., He, Y., Fujita, M., Roshchupkin, G., D'Aoust, T., et al. (2024) · Research Square

Cerebrovascular and genetic disordersMultiple Sclerosis Research Studies

Cited by 5

Low overlap of plasma and CSF protein quantitative trait loci affects protein discovery for neurological disease

Western, D., Yang, C., Timsina, J., Liu, M., Wang, C., Campbell, M. C., Kotzbauer, P., Perlmutter, J. S., Schindler, S. E., Morris, J. C., et al. (2026) · Science Translational Medicine

Genetic Associations and EpidemiologyMultiple Sclerosis Research Studies

Cited by 1