Kapur, Shitij

Psychosis as a state of aberrant salience: a framework linking biology, phenomenology and pharmacology in schizophrenia

Kapur, S. (2003) · American Journal of Psychiatry

Schizophrenia research and treatmentMental Health and Psychiatry

Cited by 2,813

The Dopamine Hypothesis of Schizophrenia: Version III--The Final Common Pathway

Howes, O. D., & Kapur, S. (2009) · Schizophrenia Bulletin

Schizophrenia research and treatmentNeurotransmitter Receptor Influence on Behavior

Cited by 2,693

Grand challenges in global mental health

Collins, P. Y., Patel, V., Joestl, S. S., March, D., Insel, T. R., Daar, A. S., Bordin, I. A., Costello, E. J., Durkin, M., Fairburn, C., et al. (2011) · Nature

Mental Health Treatment and AccessPsychiatric care and mental health services

Cited by 2,043

Schizophrenia

van Os, J., & Kapur, S. (2009) · The Lancet

Schizophrenia research and treatmentMental Health and Psychiatry

Cited by 1,971

Does Fast Dissociation From the Dopamine D 2 Receptor Explain the Action of Atypical Antipsychotics?: A New Hypothesis

Kapur, S., & Seeman, P. (2001) · American Journal of Psychiatry

Schizophrenia research and treatmentNeurotransmitter Receptor Influence on Behavior

Cited by 1,140

Relationship Between Dopamine D 2 Occupancy, Clinical Response, and Side Effects: A Double-Blind PET Study of First-Episode Schizophrenia

Kapur, S., Zipursky, R., Jones, C., Remington, G., & Houle, S. (2000) · American Journal of Psychiatry

Schizophrenia research and treatmentNeurotransmitter Receptor Influence on Behavior

Cited by 1,090

Why has it taken so long for biological psychiatry to develop clinical tests and what to do about it?

Kapur, S., Phillips, A. G., & Insel, T. R. (2012) · Molecular Psychiatry

Mental Health and PsychiatryBipolar Disorder and Treatment

Cited by 980

The Nature of Dopamine Dysfunction in Schizophrenia and What This Means for Treatment: Meta-analysis of Imaging Studies

Howes, O. D., Kambeitz, J., Kim, E., Stahl, D., Slifstein, M., Abi-Dargham, A., & Kapur, S. (2012) · Archives of General Psychiatry

Schizophrenia research and treatmentNeurotransmitter Receptor Influence on Behavior

Cited by 967

CNVs conferring risk of autism or schizophrenia affect cognition in controls

Stefansson, H., Meyer-Lindenberg, A., Steinberg, S., Magnusdottir, B., Morgen, K., Arnarsdottir, S., Bjornsdottir, G., Walters, G. B., Jonsdottir, G. A., Doyle, O. M., et al. (2014) · Nature

Genomic variations and chromosomal abnormalitiesSchizophrenia research and treatment

Cited by 699

Opposite Effects of Δ-9-Tetrahydrocannabinol and Cannabidiol on Human Brain Function and Psychopathology

Bhattacharyya, S., Morrison, P. D., Fusar-Poli, P., Martin-Santos, R., Borgwardt, S., Winton-Brown, T., Nosarti, C., O' Carroll, C. M., Seal, M., Allen, P., et al. (2010) · Neuropsychopharmacology

Cannabis and Cannabinoid ResearchPsychedelics and Drug Studies

Cited by 680

Half a century of antipsychotics and still a central role for dopamine D2 receptors

Kapur, S., & Mamo, D. (2003) · Progress in Neuro-Psychopharmacology and Biological Psychiatry

Schizophrenia research and treatmentNeurotransmitter Receptor Influence on Behavior

Cited by 638

In search of the self: a positron emission tomography study

Craik, F. I. M., Moroz, T. M., Moscovitch, M., Stuss, D. T., Winocur, G., Tulving, E., & Kapur, S. (1999) · Psychological Science

Memory Processes and InfluencesHemispheric Asymmetry in Neuroscience

Cited by 600

From dopamine to salience to psychosis—Linking biology, pharmacology and phenomenology of psychosis

Kapur, S., Mizrahi, R., & Li, M. (2005) · Schizophrenia Research

Schizophrenia research and treatmentNeurotransmitter Receptor Influence on Behavior

Cited by 512

NMDA receptor antagonists ketamine and PCP have direct effects on the dopamine D2 and serotonin 5-HT2 receptors—implications for models of schizophrenia

Kapur, S., & Seeman, P. (2002) · Molecular Psychiatry

Schizophrenia research and treatmentNeurotransmitter Receptor Influence on Behavior

Cited by 459

Direct Activation of the Ventral Striatum in Anticipation of Aversive Stimuli

Jensen, J., McIntosh, A. R., Crawley, A. P., Mikulis, D. J., Remington, G., & Kapur, S. (2003) · Neuron

Neural and Behavioral Psychology StudiesNeurotransmitter Receptor Influence on Behavior

Cited by 455

Delayed-Onset Hypothesis of Antipsychotic Action: A Hypothesis Tested and Rejected

Agid, O., Kapur, S., Arenovich, T., & Zipursky, R. B. (2003) · Archives of General Psychiatry

Schizophrenia research and treatmentNeurotransmitter Receptor Influence on Behavior

Cited by 408

5-HT2and D2Receptor Occupancy of Olanzapine in Schizophrenia: A PET Investigation

Kapur, S., Zipursky, R. B., Remington, G., Jones, C., DaSilva, J., Wilson, A. A., & Houle, S. (1998) · American Journal of Psychiatry

Schizophrenia research and treatmentNeurotransmitter Receptor Influence on Behavior

Cited by 370

Atypical antipsychotics: new directions and new challenges in the treatment of schizophrenia

Kapur, S., & Remington, G. (2001) · Annual Review of Medicine

Schizophrenia research and treatmentNeurotransmitter Receptor Influence on Behavior

Cited by 324

Increased dopamine D 2 receptor binding after long-term treatment with antipsychotics in humans: a clinical PET study

Silvestri, S., Seeman, M. V., Negrete, J.-C., Houle, S., Shammi, C. M., Remington, G. J., Kapur, S., Zipursky, R. B., Wilson, A. A., Christensen, B. K., et al. (2000) · Psychopharmacology

Schizophrenia research and treatmentNeurotransmitter Receptor Influence on Behavior

Cited by 311

Schizophrenia: More dopamine, more D 2 receptors

Seeman, P., & Kapur, S. (2000) · Proceedings of the National Academy of Sciences

Schizophrenia research and treatmentNeurotransmitter Receptor Influence on Behavior

Cited by 279

Functional Neuroanatomy of Recall and Recognition: A PET Study of Episodic Memory

Cabeza, R., Kapur, S., Craik, F. I. M., McIntosh, A. R., Houle, S., & Tulving, E. (1997) · Journal of Cognitive Neuroscience

Memory Processes and InfluencesMemory and Neural Mechanisms

Cited by 263

“Breakthrough” dopamine supersensitivity during ongoing antipsychotic treatment leads to treatment failure over time

Samaha, A.-N., Seeman, P., Stewart, J., Rajabi, H., & Kapur, S. (2007) · The Journal of Neuroscience

Schizophrenia research and treatmentNeurotransmitter Receptor Influence on Behavior

Cited by 262

The Effect of Paroxetine on 5-HT2A Receptors in Depression: An [18F]Setoperone PET Imaging Study

Meyer, J. H., Kapur, S., Eisfeld, B., Brown, G. M., Houle, S., DaSilva, J., Wilson, A. A., Rafi-Tari, S., Mayberg, H. S., & Kennedy, S. H. (2001) · American Journal of Psychiatry

Treatment of Major DepressionNeurotransmitter Receptor Influence on Behavior

Cited by 231

The formation of abnormal associations in schizophrenia: Neural and behavioral evidence

Jensen, J., Willeit, M., Zipursky, R. B., Savina, I., Smith, A. J., Menon, M., Crawley, A. P., & Kapur, S. (2008) · Neuropsychopharmacology

Schizophrenia research and treatmentNeurotransmitter Receptor Influence on Behavior

Cited by 225