Gunning, Patrick T.

A novel small-molecule disrupts Stat3 SH2 domain–phosphotyrosine interactions and Stat3-dependent tumor processes

Zhang, X., Yue, P., Fletcher, S., Zhao, W., Gunning, P. T., & Turkson, J. (2010) · Biochemical Pharmacology

Cytokine Signaling Pathways and InteractionsProtein Tyrosine Phosphatases

Cited by 179

Potent Targeting of the STAT3 Protein in Brain Cancer Stem Cells: A Promising Route for Treating Glioblastoma

Haftchenary, S., Luchman, H. A., Jouk, A. O., Veloso, A. J., Page, B. D. G., Cheng, X. R., Dawson, S. S., Grinshtein, N., Shahani, V. M., Kerman, K., et al. (2013) · ACS Medicinal Chemistry Letters

Glioma Diagnosis and TreatmentCytokine Signaling Pathways and Interactions

Cited by 126

Development of HDAC Inhibitors Exhibiting Therapeutic Potential in T-Cell Prolymphocytic Leukemia

Toutah, K., Nawar, N., Timonen, S., Sorger, H., Raouf, Y. S., Bukhari, S., von Jan, J., Ianevski, A., Gawel, J. M., Olaoye, O. O., et al. (2021) · Journal of Medicinal Chemistry

Histone Deacetylase Inhibitors ResearchChronic Lymphocytic Leukemia Research

Cited by 51

Signal transducer and activator of transcription 3 (STAT3) inhibitor, S3I-201, acts as a potent and non-selective alkylating agent

Ball, D. P., Lewis, A. M., Williams, D., Resetca, D., Wilson, D. J., & Gunning, P. T. (2016) · Oncotarget

Cytokine Signaling Pathways and InteractionsClick Chemistry and Applications

Cited by 50

Changes in signal transducer and activator of transcription 3 (STAT3) dynamics induced by complexation with pharmacological inhibitors of Src homology 2 (SH2) domain dimerization

Resetca, D., Haftchenary, S., Gunning, P. T., & Wilson, D. J. (2014) · Journal of Biological Chemistry

Cytokine Signaling Pathways and InteractionsMass Spectrometry Techniques and Applications

Cited by 47

Medicinal chemistry advances in targeting class I histone deacetylases

Abdallah, D. I., de Araujo, E. D., Patel, N. H., Hasan, L. S., Moriggl, R., Krämer, O. H., & Gunning, P. T. (2023) · Exploration of Targeted Anti-tumor Therapy

Histone Deacetylase Inhibitors ResearchEnzyme function and inhibition

Cited by 17