Xia, Menghang

The Tox21 robotic platform for the assessment of environmental chemicals – from vision to reality

Attene-Ramos, M. S., Miller, N., Huang, R., Michael, S., Itkin, M., Kavlock, R. J., Austin, C. P., Shinn, P., Simeonov, A., Tice, R. R., et al. (2013) · Drug Discovery Today

Effects and risks of endocrine disrupting chemicalsComputational Drug Discovery Methods

Cited by 255

Editor's Highlight: Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space

Judson, R., Houck, K., Martin, M., Richard, A. M., Knudsen, T. B., Shah, I., Little, S., Wambaugh, J., Woodrow Setzer, R., Kothya, P., et al. (2016) · Toxicological Sciences

Animal testing and alternativesEnvironmental Toxicology and Ecotoxicology

Cited by 232

Liver three-dimensional cellular models for high-throughput chemical testing

Yang, S., Ooka, M., Margolis, R. J., & Xia, M. (2023) · Cell Reports Methods

Drug-Induced Hepatotoxicity and Protection3D Printing in Biomedical Research

Cited by 75

Identification of Compounds for Butyrylcholinesterase Inhibition

Li, S., Li, A. J., Travers, J., Xu, T., Sakamuru, S., Klumpp-Thomas, C., Huang, R., & Xia, M. (2021) · SLAS Discovery

Cholinesterase and Neurodegenerative DiseasesEnzyme function and inhibition

Cited by 60

Application of In Vitro Metabolism Activation in High-Throughput Screening

Ooka, M., Lynch, C., & Xia, M. (2020) · International Journal of Molecular Sciences

Pharmacogenetics and Drug MetabolismDrug-Induced Hepatotoxicity and Protection

Cited by 49

Parallel evaluation of alternative skin barrier models and excised human skin for dermal absorption studies in vitro

Salminen, A. T., Davis, K. J., Felton, R. P., Nischal, N., VonTungeln, L. S., Beland, F. A., Derr, K., Brown, P. C., Ferrer, M., Katz, L. M., et al. (2023) · Toxicology in Vitro

Advancements in Transdermal Drug DeliveryContact Dermatitis and Allergies

Cited by 25

Retro Drug Design: From Target Properties to Molecular Structures

Wang, Y., Michael, S., Yang, S.-M., Huang, R., Cruz-Gutierrez, K., Zhang, Y., Zhao, J., Xia, M., Shinn, P., & Sun, H. (2022) · Journal of Chemical Information and Modeling

Computational Drug Discovery MethodsMachine Learning in Materials Science

Cited by 24

Use of Tox21 Screening Data to Evaluate the COVID-19 Drug Candidates for Their Potential Toxic Effects and Related Pathways

Sakamuru, S., Huang, R., & Xia, M. (2022) · Frontiers in Pharmacology

Computational Drug Discovery MethodsAnimal testing and alternatives

Cited by 11

In vitro profiling of pesticides within the Tox21 10K compound library for bioactivity and potential toxicity

Ngan, D. K., Xia, M., Simeonov, A., & Huang, R. (2023) · Toxicology and Applied Pharmacology

Pesticide Exposure and ToxicityEnvironmental Toxicology and Ecotoxicology

Cited by 10

​Temporal proteomic profiling of iPSC-derived human liver organoids reveals optimal maturation for drug metabolism and toxicology

Yang, S., Hao, J., Ooka, M., & Xia, M. (2026) · Scientific Reports

Drug-Induced Hepatotoxicity and ProtectionPluripotent Stem Cells Research

Cited by 5