Malik, Harmit S.

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

Gordon, D. E., Jang, G. M., Bouhaddou, M., Xu, J., Obernier, K., White, K. M., O’Meara, M. J., Rezelj, V. V., Guo, J. Z., Swaney, D. L., et al. (2020) · Nature

SARS-CoV-2 and COVID-19 ResearchComputational Drug Discovery Methods

Cited by 4,405

Positive selection of primate TRIM5 α identifies a critical species-specific retroviral restriction domain

Sawyer, S. L., Wu, L. I., Emerman, M., & Malik, H. S. (2005) · Proceedings of the National Academy of Sciences

HIV Research and TreatmentEvolution and Genetic Dynamics

Cited by 688

Rules of engagement: molecular insights from host–virus arms races

Daugherty, M. D., & Malik, H. S. (2012) · Annual Review of Genetics

Evolution and Genetic Dynamicsinterferon and immune responses

Cited by 515

Ancient adaptive evolution of the primate antiviral DNA-editing enzyme APOBEC3G

Sawyer, S. L., Emerman, M., & Malik, H. S. (2004) · PLoS Biology

HIV Research and TreatmentEvolution and Genetic Dynamics

Cited by 485

Protein kinase R reveals an evolutionary model for defeating viral mimicry

Elde, N. C., Child, S. J., Geballe, A. P., & Malik, H. S. (2009) · Nature

interferon and immune responsesEvolution and Genetic Dynamics

Cited by 260

Phylogenetic analysis of ribonuclease H domains suggests a late, chimeric origin of LTR retrotransposable elements and retroviruses

Malik, H. S., & Eickbush, T. H. (2001) · Genome Research

Chromosomal and Genetic VariationsEvolution and Genetic Dynamics

Cited by 248

Restriction of an Extinct Retrovirus by the Human TRIM5α Antiviral Protein

Kaiser, S. M., Malik, H. S., & Emerman, M. (2007) · Science

HIV Research and Treatmentinterferon and immune responses

Cited by 145

Evolution-guided identification of antiviral specificity determinants in the broadly acting interferon-induced innate immunity factor MxA

Mitchell, P. S., Patzina, C., Emerman, M., Haller, O., Malik, H. S., & Kochs, G. (2012) · Cell Host & Microbe

interferon and immune responsesVirology and Viral Diseases

Cited by 142

Convergent evolution of escape from hepaciviral antagonism in primates

Patel, M. R., Loo, Y.-M., Horner, S. M., Gale, M., & Malik, H. S. (2012) · PLoS Biology

interferon and immune responsesHepatitis C virus research

Cited by 95

The diverse evolutionary histories of domesticated metaviral capsid genes in mammals

Henriques, W. S., Young, J. M., Nemudryi, A., Nemudraia, A., Wiedenheft, B., & Malik, H. S. (2023) · Molecular Biology and Evolution

Chromosomal and Genetic VariationsEvolution and Genetic Dynamics

Cited by 31

The Diverse Evolutionary Histories of Domesticated Metaviral Capsid Genes in Mammals

Henriques, W. S., Young, J. M., Nemudryi, A., Nemudraia, A., Wiedenheft, B., & Malik, H. S. (2024) · Molecular Biology and Evolution

Chromosomal and Genetic VariationsEvolution and Genetic Dynamics

Cited by 31

Evolutionary origin and structural ligand mimicry by the inserted domain of alpha-integrin proteins

Hollis, J. A., Chan, M. C., Malik, H. S., & Campbell, M. G. (2023) · Science Advances

Cell Adhesion Molecules ResearchBiochemical and Structural Characterization

Cited by 4

Molecular exaptation by the integrin αI domain

Hollis, J. A., Chan, M. C., Malik, H. S., & Campbell, M. G. (2025) · Science Advances

Cell Adhesion Molecules ResearchBiochemical and Structural Characterization

Cited by 4