Jones, Philip H.

High burden and pervasive positive selection of somatic mutations in normal human skin

Martincorena, I., Roshan, A., Gerstung, M., Ellis, P., Van Loo, P., McLaren, S., Wedge, D. C., Fullam, A., Alexandrov, L. B., Tubio, J. M., et al. (2015) · Science

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Somatic mutant clones colonize the human esophagus with age

Martincorena, I., Fowler, J. C., Wabik, A., Lawson, A. R. J., Abascal, F., Hall, M. W. J., Cagan, A., Murai, K., Mahbubani, K., Stratton, M. R., et al. (2018) · Science

Cancer Genomics and DiagnosticsEsophageal Cancer Research and Treatment

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A single type of progenitor cell maintains normal epidermis

Clayton, E., Doupé, D. P., Klein, A. M., Winton, D. J., Simons, B. D., & Jones, P. H. (2007) · Nature

Hair Growth and DisordersSkin and Cellular Biology Research

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Developmental cell programs are co-opted in inflammatory skin disease

Reynolds, G., Vegh, P., Fletcher, J., Poyner, E. F. M., Stephenson, E., Goh, I., Botting, R. A., Huang, N., Olabi, B., Dubois, A., et al. (2021) · Science

Dermatology and Skin DiseasesPsoriasis: Treatment and Pathogenesis

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Mutant clones in normal epithelium outcompete and eliminate emerging tumours

Colom, B., Herms, A., Hall, M. W. J., Dentro, S. C., King, C., Sood, R. K., Alcolea, M. P., Piedrafita, G., Fernandez-Antoran, D., Ong, S. H., et al. (2021) · Nature

Cancer Genomics and DiagnosticsCancer Cells and Metastasis

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Notch1 mutations drive clonal expansion in normal esophageal epithelium but impair tumor growth

Abby, E., Dentro, S. C., Hall, M. W. J., Fowler, J. C., Ong, S. H., Sood, R., Herms, A., Piedrafita, G., Abnizova, I., Siebel, C. W., et al. (2023) · Nature Genetics

Developmental Biology and Gene RegulationCancer Genomics and Diagnostics

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