Civelek, Mete

Integrative approaches for large-scale transcriptome-wide association studies

Gusev, A., Ko, A., Shi, H., Bhatia, G., Chung, W., Penninx, B. W. J. H., Jansen, R., de Geus, E. J. C., Boomsma, D. I., Wright, F. A., et al. (2016) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 2,479

CD47-blocking antibodies restore phagocytosis and prevent atherosclerosis

Kojima, Y., Volkmer, J.-P., McKenna, K., Civelek, M., Lusis, A. J., Miller, C. L., Direnzo, D., Nanda, V., Ye, J., Connolly, A. J., et al. (2016) · Nature

Phagocytosis and Immune RegulationAtherosclerosis and Cardiovascular Diseases

Cited by 683

Systems genetics approaches to understand complex traits

Civelek, M., & Lusis, A. J. (2014) · Nature Reviews Genetics

Bioinformatics and Genomic NetworksGenetic Associations and Epidemiology

Cited by 621

Genetic Control of Obesity and Gut Microbiota Composition in Response to High-Fat, High-Sucrose Diet in Mice

Parks, B. W., Nam, E., Org, E., Kostem, E., Norheim, F., Hui, S. T., Pan, C., Civelek, M., Rau, C. D., Bennett, B. J., et al. (2013) · Cell Metabolism

Gut microbiota and healthNutrition, Genetics, and Disease

Cited by 544

The TMAO-Producing Enzyme Flavin-Containing Monooxygenase 3 Regulates Obesity and the Beiging of White Adipose Tissue

Schugar, R. C., Shih, D. M., Warrier, M., Helsley, R. N., Burrows, A., Ferguson, D., Brown, A. L., Gromovsky, A. D., Heine, M., Chatterjee, A., et al. (2017) · Cell Reports

Gut microbiota and healthAdipokines, Inflammation, and Metabolic Diseases

Cited by 291

Integrative Genomics Reveals Novel Molecular Pathways and Gene Networks for Coronary Artery Disease

Mäkinen, V.-P., Civelek, M., Meng, Q., Zhang, B., Zhu, J., Levian, C., Huan, T., Segrè, A. V., Ghosh, S., Vivar, J., et al. (2014) · PLoS Genetics

Bioinformatics and Genomic NetworksGenetic Associations and Epidemiology

Cited by 196

Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition

Small, K. S., Todorčević, M., Civelek, M., El-Sayed Moustafa, J. S., Wang, X., Simon, M. M., Fernandez-Tajes, J., Mahajan, A., Horikoshi, M., Hugill, A., et al. (2018) · Nature Genetics

Adipokines, Inflammation, and Metabolic DiseasesGenetic Associations and Epidemiology

Cited by 168

The Hybrid Mouse Diversity Panel: a resource for systems genetics analyses of metabolic and cardiovascular traits

Lusis, A. J., Seldin, M. M., Allayee, H., Bennett, B. J., Civelek, M., Davis, R. C., Eskin, E., Farber, C. R., Hui, S., Mehrabian, M., et al. (2016) · Journal of Lipid Research

Genetic Mapping and Diversity in Plants and AnimalsGenetic Associations and Epidemiology

Cited by 158

Genetic Variation Determines PPARγ Function and Anti-diabetic Drug Response In Vivo

Soccio, R. E., Chen, E. R., Rajapurkar, S. R., Safabakhsh, P., Marinis, J. M., Dispirito, J. R., Emmett, M. J., Briggs, E. R., Fang, B., Everett, L. J., et al. (2015) · Cell

Peroxisome Proliferator-Activated ReceptorsGenetic Associations and Epidemiology

Cited by 117

Network for Activation of Human Endothelial Cells by Oxidized Phospholipids: A Critical Role of Heme Oxygenase 1

Romanoski, C. E., Che, N., Yin, F., Mai, N., Pouldar, D., Civelek, M., Pan, C., Lee, S., Vakili, L., Yang, W.-P., et al. (2011) · Circulation Research

Atherosclerosis and Cardiovascular DiseasesNitric Oxide and Endothelin Effects

Cited by 115

Prediction of Causal Candidate Genes in Coronary Artery Disease Loci

Brænne, I., Civelek, M., Vilne, B., Di Narzo, A., Johnson, A. D., Zhao, Y., Reiz, B., Codoni, V., Webb, T. R., Foroughi Asl, H., et al. (2015) · Arteriosclerosis, Thrombosis, and Vascular Biology

Genetic Associations and EpidemiologyBioinformatics and Genomic Networks

Cited by 109

Genetic regulation of human adipose microRNA expression and its consequences for metabolic traits

Civelek, M., Hagopian, R., Pan, C., Che, N., Yang, W.-P., Kayne, P. S., Saleem, N. K., Cederberg, H., Kuusisto, J., Gargalovic, P. S., et al. (2013) · Human Molecular Genetics

MicroRNA in disease regulationGenetic Associations and Epidemiology

Cited by 89

A Strategy for Discovery of Endocrine Interactions with Application to Whole-Body Metabolism

Seldin, M. M., Koplev, S., Rajbhandari, P., Vergnes, L., Rosenberg, G. M., Meng, Y., Pan, C., Phuong, T. M. N., Gharakhanian, R., Che, N., et al. (2018) · Cell Metabolism

Adipose Tissue and MetabolismBioinformatics and Genomic Networks

Cited by 84