Systems genetics approaches to understand complex traits

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Metabolite profiles and the risk of developing diabetes

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Annotation of functional variation in personal genomes using RegulomeDB

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Metabolomics: the apogee of the omics trilogy

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Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression

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HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants

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The Genetic Landscape of a Cell

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The Strategy of the Genes

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Transcriptome and genome sequencing uncovers functional variation in humans

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Genome-wide association study of 107 phenotypes in Arabidopsis thaliana inbred lines

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Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

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Wisdom of crowds for robust gene network inference

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Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease

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The mystery of missing heritability: Genetic interactions create phantom heritability

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Genetic Dissection of Transcriptional Regulation in Budding Yeast

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Phenomics: the next challenge

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From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus

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An integrative genomics approach to infer causal associations between gene expression and disease

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Data and Theory Point to Mainly Additive Genetic Variance for Complex Traits

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Human metabolic individuality in biomedical and pharmaceutical research

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DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines

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Molecular networks as sensors and drivers of common human diseases

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Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum

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Identification of Cd36 (Fat) as an insulin-resistance gene causing defective fatty acid and glucose metabolism in hypertensive rats

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Linking disease associations with regulatory information in the human genomePreprint

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Microbial conversion of choline to trimethylamine requires a glycyl radical enzyme

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Sequential Application of Anticancer Drugs Enhances Cell Death by Rewiring Apoptotic Signaling Networks

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DNase I sensitivity QTLs are a major determinant of human expression variation

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Comparative analysis of proteome and transcriptome variation in mouse

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The landscape of genetic complexity across 5,700 gene expression traits in yeast

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Genome-wide association study identifies multiple loci influencing human serum metabolite levels

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Integrating large-scale functional genomic data to dissect the complexity of yeast regulatory networks

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Genetic Control of Obesity and Gut Microbiota Composition in Response to High-Fat, High-Sucrose Diet in Mice

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Integrated transcriptional profiling and linkage analysis for identification of genes underlying disease

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Systems genetics of complex traits in Drosophila melanogaster

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A genome-wide association study identifies protein quantitative trait loci (pQTLs)

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Circuitry and Dynamics of Human Transcription Factor Regulatory Networks

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The diversity outbred mouse population

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Identification of Genetic Variants That Affect Histone Modifications in Human Cells

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Finding the sources of missing heritability in a yeast cross

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Gene–Environment Interaction in Yeast Gene Expression

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Genetic architecture of quantitative traits in mice, flies, and humansPreprint

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Variation and genetic control of protein abundance in humans

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Genetic basis of proteome variation in yeast

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Epistasis dominates the genetic architecture of Drosophila quantitative traits

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Extensive Variation in Chromatin States Across Humans

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Coordinated Effects of Sequence Variation on DNA Binding, Chromatin Structure, and Transcription

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Mitochondrial deficiency and cardiac sudden death in mice lacking the MEF2A transcription factor

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Identification of an imprinted master trans regulator at the KLF14 locus related to multiple metabolic phenotypes

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A high-resolution association mapping panel for the dissection of complex traits in micePreprint

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Post‐Translational Modification of Proteins

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Effect of natural genetic variation on enhancer selection and function

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Progress and prospects in rat genetics: a community view

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Systematic Mapping of Genetic Interaction Networks

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Validation of candidate causal genes for obesity that affect shared metabolic pathways and networks

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A network view of disease and compound screening

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A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk

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Hyperglycemia and a Common Variant of GCKR Are Associated With the Levels of Eight Amino Acids in 9,369 Finnish Men

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Human Disease-Associated Genetic Variation Impacts Large Intergenic Non-Coding RNA Expression

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Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions

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System-wide molecular evidence for phenotypic buffering in Arabidopsis

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The Genotype-Tissue Expression (GTEx) project

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Genetic architecture of complex traits: Large phenotypic effects and pervasive epistasis

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Selection at Linked Sites Shapes Heritable Phenotypic Variation in C. elegans

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A diurnal serum lipid integrates hepatic lipogenesis and peripheral fatty acid use

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Genotype to phenotype: lessons from model organisms for human genetics

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A statin-dependent QTL for GATM expression is associated with statin-induced myopathy

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Genetic analysis of radiation-induced changes in human gene expression

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Elucidating the Role of Gonadal Hormones in Sexually Dimorphic Gene Coexpression Networks

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Genetic Analysis of Human Traits In Vitro: Drug Response and Gene Expression in Lymphoblastoid Cell Lines

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Genetic dissection of a model complex trait using the Drosophila Synthetic Population ResourcePreprint

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Stitching together multiple data dimensions reveals interacting metabolomic and transcriptomic networks that modulate cell regulation

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