Kim, Seung K.

The human cell atlas

Regev, A., Teichmann, S. A., Lander, E. S., Amit, I., Benoist, C., Birney, E., Bodenmiller, B., Campbell, P., Carninci, P., Clatworthy, M., et al. (2017) · eLife

Single-cell and spatial transcriptomicsGene Regulatory Network Analysis

Cited by 2,232

A single-cell transcriptomic atlas characterizes ageing tissues in the mouse

The Tabula Muris Consortium, Almanzar, N., Antony, J., Baghel, A. S., Bakerman, I., Bansal, I., Barres, B. A., Beachy, P. A., Berdnik, D., Bilen, B., et al. (2020) · Nature

Single-cell and spatial transcriptomicsGenetics, Aging, and Longevity in Model Organisms

Cited by 1,247

Ablation of Insulin-Producing Neurons in Flies: Growth and Diabetic Phenotypes

Rulifson, E. J., Kim, S. K., & Nusse, R. (2002) · Science

Neurobiology and Insect Physiology ResearchPancreatic function and diabetes

Cited by 1,064

The Tabula Sapiens: A multiple-organ, single-cell transcriptomic atlas of humans

The Tabula Sapiens Consortium*, Jones, R. C., Karkanias, J., Krasnow, M. A., Pisco, A. O., Quake, S. R., Salzman, J., Yosef, N., Bulthaup, B., Brown, P., et al. (2022) · Science

Single-cell and spatial transcriptomicsGenomics and Chromatin Dynamics

Cited by 1,056

NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21

Arron, J. R., Winslow, M. M., Polleri, A., Chang, C.-P., Wu, H., Gao, X., Neilson, J. R., Chen, L., Heit, J. J., Kim, S. K., et al. (2006) · Nature

Down syndrome and intellectual disability researchSignaling Pathways in Disease

Cited by 698

Ageing hallmarks exhibit organ-specific temporal signatures

Schaum, N., Lehallier, B., Hahn, O., Pálovics, R., Hosseinzadeh, S., Lee, S. E., Sit, R., Lee, D. P., Losada, P. M., Zardeneta, M. E., et al. (2020) · Nature

Genetics, Aging, and Longevity in Model OrganismsSingle-cell and spatial transcriptomics

Cited by 671

Notochord repression of endodermal Sonic hedgehog permits pancreas development

Hebrok, M., Kim, S. K., & Melton, D. A. (1998) · Genes & Development

Hedgehog Signaling Pathway StudiesDevelopmental Biology and Gene Regulation

Cited by 628

Single-Cell Analysis of Human Pancreas Reveals Transcriptional Signatures of Aging and Somatic Mutation Patterns

Enge, M., Arda, H. E., Mignardi, M., Beausang, J., Bottino, R., Kim, S. K., & Quake, S. R. (2017) · Cell

Single-cell and spatial transcriptomicsPancreatic function and diabetes

Cited by 568

Regulation of pancreas development by hedgehog signaling

Hebrok, M., Kim, S. K., St-Jacques, B., McMahon, A. P., & Melton, D. A. (2000) · Development

Hedgehog Signaling Pathway StudiesPancreatic function and diabetes

Cited by 412

Notochord to endoderm signaling is required for pancreas development

Kim, S. K., Hebrok, M., & Melton, D. A. (1997) · Development

Developmental Biology and Gene RegulationPancreatic function and diabetes

Cited by 405

Polycomb protein Ezh2 regulates pancreatic β-cell Ink4a/Arf expression and regeneration in diabetes mellitus

Chen, H., Gu, X., Su, I.-H., Bottino, R., Contreras, J. L., Tarakhovsky, A., & Kim, S. K. (2009) · Genes & Development

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 366

Menin Controls Growth of Pancreatic ß-Cells in Pregnant Mice and Promotes Gestational Diabetes Mellitus

Karnik, S. K., Chen, H., McLean, G. W., Heit, J. J., Gu, X., Zhang, A. Y., Fontaine, M., Yen, M. H., & Kim, S. K. (2007) · Science

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 353

PDGF signalling controls age-dependent proliferation in pancreatic β-cells

Chen, H., Gu, X., Liu, Y., Wang, J., Wirt, S. E., Bottino, R., Schorle, H., Sage, J., & Kim, S. K. (2011) · Nature

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 278

Single-nucleus and in situ RNA-sequencing reveal cell topographies in the human pancreas

Tosti, L., Hang, Y., Debnath, O., Tiesmeyer, S., Trefzer, T., Steiger, K., Ten, F. W., Lukassen, S., Ballke, S., Kühl, A. A., et al. (2021) · Gastroenterology

Single-cell and spatial transcriptomicsPancreatic function and diabetes

Cited by 228

Age-Dependent Pancreatic Gene Regulation Reveals Mechanisms Governing Human β Cell Function

Arda, H. E., Li, L., Tsai, J., Torre, E. A., Rosli, Y., Peiris, H., Spitale, R. C., Dai, C., Gu, X., Qu, K., et al. (2016) · Cell Metabolism

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 222

Human COL7A1 -corrected induced pluripotent stem cells for the treatment of recessive dystrophic epidermolysis bullosa

Sebastiano, V., Zhen, H. H., Haddad, B., Bashkirova, E., Melo, S. P., Wang, P., Leung, T. L., Siprashvili, Z., Tichy, A., Li, J., et al. (2014) · Science Translational Medicine

Pluripotent Stem Cells ResearchSkin and Cellular Biology Research

Cited by 213

Activin receptor patterning of foregut organogenesis

Kim, S. K., Hebrok, M., Li, E., Oh, S. P., Schrewe, H., Harmon, E. B., Lee, J. S., & Melton, D. A. (2000) · Genes & Development

Developmental Biology and Gene RegulationPancreatic function and diabetes

Cited by 212

A p53 Super-tumor Suppressor Reveals a Tumor Suppressive p53-Ptpn14-Yap Axis in Pancreatic Cancer

Mello, S. S., Valente, L. J., Raj, N., Seoane, J. A., Flowers, B. M., McClendon, J., Bieging-Rolett, K. T., Lee, J., Ivanochko, D., Kozak, M. M., et al. (2017) · Cancer Cell

Cancer-related Molecular PathwaysHippo pathway signaling and YAP/TAZ

Cited by 179

Intrinsic Regulators of Pancreatic β-Cell Proliferation

Heit, J. J., Karnik, S. K., & Kim, S. K. (2006) · Annual Review of Cell and Developmental Biology

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 165

Molecular hallmarks of heterochronic parabiosis at single-cell resolution

Pálovics, R., Keller, A., Schaum, N., Tan, W., Fehlmann, T., Borja, M., Kern, F., Bonanno, L., Calcuttawala, K., Webber, J., et al. (2022) · Nature

Genetics, Aging, and Longevity in Model OrganismsSingle-cell and spatial transcriptomics

Cited by 153

Suppression of Insulin Production and Secretion by a Decretin Hormone

Alfa, R. W., Park, S., Skelly, K.-R., Poffenberger, G., Jain, N., Gu, X., Kockel, L., Wang, J., Liu, Y., Powers, A. C., et al. (2015) · Cell Metabolism

Pancreatic function and diabetesNeuropeptides and Animal Physiology

Cited by 150

Gestational Diabetes Mellitus From Inactivation of Prolactin Receptor and MafB in Islet β-Cells

Banerjee, R. R., Cyphert, H. A., Walker, E. M., Chakravarthy, H., Peiris, H., Gu, X., Liu, Y., Conrad, E., Goodrich, L., Stein, R. W., et al. (2016) · Diabetes

Pancreatic function and diabetesGestational Diabetes Research and Management

Cited by 131

Cell types of origin of the cell-free transcriptome

Vorperian, S. K., Moufarrej, M. N., Tabula Sapiens Consortium, Overall Project Direction and Coordination, Jones, R. C., Karkanias, J., Krasnow, M., Pisco, A. O., Quake, S. R., Salzman, J., et al. (2022) · Nature Biotechnology

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 116

Topical hypochlorite ameliorates NF-κB–mediated skin diseases in mice

Leung, T. H., Zhang, L. F., Wang, J., Ning, S., Knox, S. J., & Kim, S. K. (2013) · Journal of Clinical Investigation

NF-κB Signaling PathwaysSkin Protection and Aging

Cited by 107