Turner, Nigel

Declining NAD+ Induces a Pseudohypoxic State Disrupting Nuclear-Mitochondrial Communication during Aging

Gomes, A. P., Price, N. L., Ling, A. J. Y., Moslehi, J. J., Montgomery, M. K., Rajman, L., White, J. P., Teodoro, J. S., Wrann, C. D., Hubbard, B. P., et al. (2013) · Cell

Sirtuins and Resveratrol in MedicineMitochondrial Function and Pathology

Cited by 1,482

The Ratio of Macronutrients, Not Caloric Intake, Dictates Cardiometabolic Health, Aging, and Longevity in Ad Libitum-Fed Mice

Solon-Biet, S. M., McMahon, A. C., Ballard, J. W. O., Ruohonen, K., Wu, L. E., Cogger, V. C., Warren, A., Huang, X., Pichaud, N., Melvin, R. G., et al. (2014) · Cell Metabolism

Genetics, Aging, and Longevity in Model OrganismsDietary Effects on Health

Cited by 904

Insulin resistance is a cellular antioxidant defense mechanism

Hoehn, K. L., Salmon, A. B., Hohnen-Behrens, C., Turner, N., Hoy, A. J., Maghzal, G. J., Stocker, R., Van Remmen, H., Kraegen, E. W., Cooney, G. J., et al. (2009) · Proceedings of the National Academy of Sciences

Metabolism, Diabetes, and CancerMitochondrial Function and Pathology

Cited by 540

Berberine and Its More Biologically Available Derivative, Dihydroberberine, Inhibit Mitochondrial Respiratory Complex I

Turner, N., Li, J.-Y., Gosby, A., To, S. W. C., Cheng, Z., Miyoshi, H., Taketo, M. M., Cooney, G. J., Kraegen, E. W., James, D. E., et al. (2008) · Diabetes

Berberine and alkaloids researchMetabolism, Diabetes, and Cancer

Cited by 535

Excess Lipid Availability Increases Mitochondrial Fatty Acid Oxidative Capacity in Muscle

Turner, N., Bruce, C. R., Beale, S. M., Hoehn, K. L., So, T., Rolph, M. S., & Cooney, G. J. (2007) · Diabetes

Adipose Tissue and MetabolismMetabolism, Diabetes, and Cancer

Cited by 520

Impairment of an endothelial NAD(+)-H2S signaling network is a reversible cause of vascular aging

Das, A., Huang, G. X., Bonkowski, M. S., Longchamp, A., Li, C., Schultz, M. B., Kim, L.-J., Osborne, B., Joshi, S., Lu, Y., et al. (2018) · Cell

Nitric Oxide and Endothelin EffectsSirtuins and Resveratrol in Medicine

Cited by 496

Distinct patterns of tissue-specific lipid accumulation during the induction of insulin resistance in mice by high-fat feeding

Turner, N., Kowalski, G. M., Leslie, S. J., Risis, S., Yang, C., Lee-Young, R. S., Babb, J. R., Meikle, P. J., Lancaster, G. I., Henstridge, D. C., et al. (2013) · Diabetologia

Diet, Metabolism, and DiseaseAdipokines, Inflammation, and Metabolic Diseases

Cited by 430

Overexpression of carnitine palmitoyltransferase-1 in skeletal muscle is sufficient to enhance fatty acid oxidation and improve high-fat diet–induced insulin resistance

Bruce, C. R., Hoy, A. J., Turner, N., Watt, M. J., Allen, T. L., Carpenter, K., Cooney, G. J., Febbraio, M. A., & Kraegen, E. W. (2009) · Diabetes

Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism

Cited by 363

Markers of mitochondrial biogenesis and metabolism are lower in overweight and obese insulin-resistant subjects.

Heilbronn, L. K., Gan, S. K., Turner, N., Campbell, L. V., & Chisholm, D. J. (2007) · The Journal of Clinical Endocrinology & Metabolism

Adipose Tissue and MetabolismMetabolism, Diabetes, and Cancer

Cited by 184

Acute or chronic upregulation of mitochondrial fatty acid oxidation has no net effect on whole-body energy expenditure or adiposity

Hoehn, K. L., Turner, N., Swarbrick, M. M., Wilks, D., Preston, E., Phua, Y., Joshi, H., Furler, S. M., Larance, M., Hegarty, B. D., et al. (2010) · Cell Metabolism

Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism

Cited by 156

Mitochondrial uncoupler BAM15 reverses diet-induced obesity and insulin resistance in mice

Alexopoulos, S. J., Chen, S.-Y., Brandon, A. E., Salamoun, J. M., Byrne, F. L., Garcia, C. J., Beretta, M., Olzomer, E. M., Shah, D. P., Philp, A. M., et al. (2020) · Nature Communications

Adipose Tissue and MetabolismPharmacology and Obesity Treatment

Cited by 137

Lipid and insulin infusion-induced skeletal muscle insulin resistance is likely due to metabolic feedback and not changes in IRS-1, Akt, or AS160 phosphorylation

Hoy, A. J., Brandon, A. E., Turner, N., Watt, M. J., Bruce, C. R., Cooney, G. J., & Kraegen, E. W. (2009) · American Journal of Physiology-Endocrinology and Metabolism

Metabolism, Diabetes, and CancerDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 92

Altered feeding differentially regulates circadian rhythms and energy metabolism in liver and muscle of rats

Reznick, J., Preston, E., Wilks, D. L., Beale, S. M., Turner, N., & Cooney, G. J. (2013) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Circadian rhythm and melatoninDietary Effects on Health

Cited by 86

Overexpression of carnitine palmitoyltransferase I in skeletal muscle in vivo increases fatty acid oxidation and reduces triacylglycerol esterification

Bruce, C. R., Brolin, C., Turner, N., Cleasby, M. E., van der Leij, F. R., Cooney, G. J., & Kraegen, E. W. (2007) · American Journal of Physiology-Endocrinology and Metabolism

Adipose Tissue and MetabolismLipid metabolism and biosynthesis

Cited by 72

Modeling insulin resistance in rodents by alterations in diet: What have high-fat and high-calorie diets revealed?

Small, L., Brandon, A. E., Turner, N., & Cooney, G. J. (2018) · American Journal of Physiology-Endocrinology and Metabolism

Diet, Metabolism, and DiseaseAdipokines, Inflammation, and Metabolic Diseases

Cited by 72

Muscle insulin resistance: a case of fat overconsumption, not mitochondrial dysfunction

Kraegen, E. W., Cooney, G. J., & Turner, N. (2008) · Proceedings of the National Academy of Sciences

Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism

Cited by 62

Amelioration of lipid-induced insulin resistance in rat skeletal muscle by overexpression of Pgc-1β involves reductions in long-chain acyl-CoA levels and oxidative stress

Wright, L. E., Brandon, A. E., Hoy, A. J., Forsberg, G.-B., Lelliott, C. J., Reznick, J., Löfgren, L., Oscarsson, J., Strömstedt, M., Cooney, G. J., et al. (2011) · Diabetologia

Adipose Tissue and MetabolismMetabolism, Diabetes, and Cancer

Cited by 57

A novel chemical uncoupler ameliorates obesity and related phenotypes in mice with diet-induced obesity by modulating energy expenditure and food intake

Fu, Y.-Y., Zhang, M., Turner, N., Zhang, L.-N., Dong, T.-C., Gu, M., Leslie, S. J., Li, J.-Y., Nan, F.-J., & Li, J. (2013) · Diabetologia

Adipose Tissue and MetabolismMitochondrial Function and Pathology

Cited by 35