Bergamini, Giovanna

Catalytic in vivo protein knockdown by small-molecule PROTACs

Bondeson, D. P., Mares, A., Smith, I. E. D., Ko, E., Campos, S., Miah, A. H., Mulholland, K. E., Routly, N., Buckley, D. L., Gustafson, J. L., et al. (2015) · Nature Chemical Biology

Protein Degradation and InhibitorsUbiquitin and proteasome pathways

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Design of amidobenzimidazole STING receptor agonists with systemic activity

Ramanjulu, J. M., Pesiridis, G. S., Yang, J., Concha, N., Singhaus, R., Zhang, S.-Y., Tran, J.-L., Moore, P., Lehmann, S., Eberl, H. C., et al. (2018) · Nature

interferon and immune responsesImmunotherapy and Immune Responses

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Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes

Bantscheff, M., Hopf, C., Savitski, M. M., Dittmann, A., Grandi, P., Michon, A.-M., Schlegl, J., Abraham, Y., Becher, I., Bergamini, G., et al. (2011) · Nature Biotechnology

Histone Deacetylase Inhibitors ResearchAdvanced Proteomics Techniques and Applications

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The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis

Woodcock, H. V., Eley, J. D., Guillotin, D., Platé, M., Nanthakumar, C. B., Martufi, M., Peace, S., Joberty, G., Poeckel, D., Good, R. B., et al. (2019) · Nature Communications

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisPI3K/AKT/mTOR signaling in cancer

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Identifying drug targets in tissues and whole blood with thermal-shift profiling

Perrin, J., Werner, T., Kurzawa, N., Rutkowska, A., Childs, D. D., Kalxdorf, M., Poeckel, D., Stonehouse, E., Strohmer, K., Heller, B., et al. (2020) · Nature Biotechnology

Advanced Proteomics Techniques and ApplicationsProtein Degradation and Inhibitors

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Discovery of GSK8612, a Highly Selective and Potent TBK1 Inhibitor

Thomson, D. W., Poeckel, D., Zinn, N., Rau, C., Strohmer, K., Wagner, A. J., Graves, A. P., Perrin, J., Bantscheff, M., Duempelfeld, B., et al. (2019) · ACS Medicinal Chemistry Letters

interferon and immune responsesImmune Response and Inflammation

Cited by 103

Network integration of thermal proteome profiling with multi-omics data decodes PARP inhibition

Burtscher, M. L., Gade, S., Garrido-Rodriguez, M., Rutkowska, A., Werner, T., Eberl, H. C., Petretich, M., Knopf, N., Zirngibl, K., Grandi, P., et al. (2024) · Molecular Systems Biology

Advanced Proteomics Techniques and ApplicationsBioinformatics and Genomic Networks

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