Yu, Dihua

PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients

Nagata, Y., Lan, K.-H., Zhou, X., Tan, M., Esteva, F. J., Sahin, A. A., Klos, K. S., Li, P., Monia, B. P., Nguyen, N. T., et al. (2004) · Cancer Cell

HER2/EGFR in Cancer ResearchPI3K/AKT/mTOR signaling in cancer

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Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth

Zhang, L., Zhang, S., Yao, J., Lowery, F. J., Zhang, Q., Huang, W.-C., Li, P., Li, M., Wang, X., Zhang, C., et al. (2015) · Nature

Extracellular vesicles in diseaseMicroRNA in disease regulation

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Deubiquitination and Stabilization of PD-L1 by CSN5

Lim, S.-O., Li, C.-W., Xia, W., Cha, J.-H., Chan, L.-C., Wu, Y., Chang, S.-S., Lin, W.-C., Hsu, J.-M., Hsu, Y.-H., et al. (2016) · Cancer Cell

Cancer Immunotherapy and BiomarkersUbiquitin and proteasome pathways

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Combating trastuzumab resistance by targeting SRC, a common node downstream of multiple resistance pathways

Zhang, S., Huang, W.-C., Li, P., Guo, H., Poh, S.-B., Brady, S. W., Xiong, Y., Tseng, L.-M., Li, S.-H., Ding, Z., et al. (2011) · Nature Medicine

HER2/EGFR in Cancer ResearchLung Cancer Treatments and Mutations

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PTEN, PIK3CA, p-AKT, and p-p70S6K Status

Esteva, F. J., Guo, H., Zhang, S., Santa-Maria, C., Stone, S., Lanchbury, J. S., Sahin, A. A., Hortobagyi, G. N., & Yu, D. (2010) · The American Journal of Pathology

HER2/EGFR in Cancer ResearchPI3K/AKT/mTOR signaling in cancer

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Phase I/II study of trastuzumab in combination with everolimus (RAD001) in patients with HER2-overexpressing metastatic breast cancer who progressed on trastuzumab-based therapy

Morrow, P. K., Wulf, G. M., Ensor, J., Booser, D. J., Moore, J. A., Flores, P. R., Xiong, Y., Zhang, S., Krop, I. E., Winer, E. P., et al. (2011) · Journal of Clinical Oncology

HER2/EGFR in Cancer ResearchPI3K/AKT/mTOR signaling in cancer

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Lineage Infidelity of MDA-MB-435 Cells

Sellappan, S., Grijalva, R., Zhou, X., Yang, W., Eli, M. B., Mills, G. B., & Yu, D. (2004) · Cancer Research

Cancer Cells and MetastasisBreast Lesions and Carcinomas

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Vitamin E enhances cancer immunotherapy by reinvigorating dendritic cells via targeting checkpoint SHP1.

Yuan, X., Duan, Y., Xiao, Y., Sun, K., Qi, Y., Zhang, Y., Ahmed, Z., Moiani, D., Yao, J., Li, H., et al. (2022) · Cancer Discovery

Immunotherapy and Immune ResponsesCancer Immunotherapy and Biomarkers

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Cytoplasmic expression of p21CIP1/WAF1 is correlated with IKKβ overexpression in human breast cancers

Ping, B., He, X., Xia, W., Lee, D.-F., Wei, Y., Yu, D., Mills, G., Shi, D., & Hung, M.-C. (2006) · International Journal of Oncology

NF-κB Signaling PathwaysCancer-related Molecular Pathways

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