Silver, David L.

Mfsd2a is a transporter for the essential omega-3 fatty acid docosahexaenoic acid

Nguyen, L. N., Ma, D., Shui, G., Wong, P., Cazenave-Gassiot, A., Zhang, X., Wenk, M. R., Goh, E. L. K., & Silver, D. L. (2014) · Nature

Barrier Structure and Function StudiesFatty Acid Research and Health

Cited by 1,048

The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression

Nakae, J., Kitamura, T., Silver, D. L., & Accili, D. (2001) · Journal of Clinical Investigation

FOXO transcription factor regulationMetabolism, Diabetes, and Cancer

Cited by 652

Evolutionarily conserved gene family important for fat storage

Kadereit, B., Kumar, P., Wang, W.-J., Miranda, D., Snapp, E. L., Severina, N., Torregroza, I., Evans, T., & Silver, D. L. (2008) · Proceedings of the National Academy of Sciences

Lipid metabolism and biosynthesisLipid metabolism and disorders

Cited by 252

Inactivating mutations in MFSD2A, required for omega-3 fatty acid transport in brain, cause a lethal microcephaly syndrome

Guemez-Gamboa, A., Nguyen, L. N., Yang, H., Zaki, M. S., Kara, M., Ben-Omran, T., Akizu, N., Rosti, R. O., Rosti, B., Scott, E., et al. (2015) · Nature Genetics

Barrier Structure and Function StudiesFatty Acid Research and Health

Cited by 225

Mfsd2a is a transporter for the essential ω-3 fatty acid docosahexaenoic acid (DHA) in Eye and is important for photoreceptor cell development

Wong, B. H., Chan, J. P., Cazenave-Gassiot, A., Poh, R. W., Foo, J. C., Galam, D. L. A., Ghosh, S., Nguyen, L. N., Barathi, V. A., Yeo, S. W., et al. (2016) · Journal of Biological Chemistry

Retinal Development and DisordersFatty Acid Research and Health

Cited by 155

A partially inactivating mutation in the sodium-dependent lysophosphatidylcholine transporter MFSD2A causes a non-lethal microcephaly syndrome

Alakbarzade, V., Hameed, A., Quek, D. Q. Y., Chioza, B. A., Baple, E. L., Cazenave-Gassiot, A., Nguyen, L. N., Wenk, M. R., Ahmad, A. Q., Sreekantan-Nair, A., et al. (2015) · Nature Genetics

Barrier Structure and Function StudiesMetabolism and Genetic Disorders

Cited by 144

Fat Storage-inducing Transmembrane Protein 2 Is Required for Normal Fat Storage in Adipose Tissue

Miranda, D. A., Kim, J.-H., Nguyen, L. N., Cheng, W., Tan, B. C., Goh, V. J., Tan, J. S. Y., Yaligar, J., KN, B. P., Velan, S. S., et al. (2014) · Journal of Biological Chemistry

Lipid metabolism and biosynthesisAdipose Tissue and Metabolism

Cited by 71

Destabilization of β Cell FIT2 by saturated fatty acids alter lipid droplet numbers and contribute to ER stress and diabetes

Zheng, X., Ho, Q. W. C., Chua, M., Stelmashenko, O., Yeo, X. Y., Muralidharan, S., Torta, F., Chew, E. G. Y., Lian, M. M., Foo, J. N., et al. (2022) · Proceedings of the National Academy of Sciences

Pancreatic function and diabetesLipid metabolism and biosynthesis

Cited by 48