Maertens, Goedele N.

HIV-1 Integrase Forms Stable Tetramers and Associates with LEDGF/p75 Protein in Human Cells

Cherepanov, P., Maertens, G., Proost, P., Devreese, B., Van Beeumen, J., Engelborghs, Y., De Clercq, E., & Debyser, Z. (2003) · Journal of Biological Chemistry

HIV Research and TreatmentHIV/AIDS drug development and treatment

Cited by 704

LEDGF/p75 Is Essential for Nuclear and Chromosomal Targeting of HIV-1 Integrase in Human Cells

Maertens, G., Cherepanov, P., Pluymers, W., Busschots, K., De Clercq, E., Debyser, Z., & Engelborghs, Y. (2003) · Journal of Biological Chemistry

HIV Research and TreatmentHIV/AIDS drug development and treatment

Cited by 493

Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS

Barradas, M., Anderton, E., Acosta, J. C., Li, S., Banito, A., Rodriguez-Niedenführ, M., Maertens, G., Banck, M., Zhou, M.-M., Walsh, M. J., et al. (2009) · Genes & Development

Epigenetics and DNA MethylationTelomeres, Telomerase, and Senescence

Cited by 352

The mechanism of retroviral integration from X-ray structures of its key intermediates

Maertens, G. N., Hare, S., & Cherepanov, P. (2010) · Nature

HIV Research and TreatmentHIV/AIDS drug development and treatment

Cited by 296

Solution structure of the HIV-1 integrase-binding domain in LEDGF/p75

Cherepanov, P., Sun, Z.-Y. J., Rahman, S., Maertens, G., Wagner, G., & Engelman, A. (2005) · Nature Structural & Molecular Biology

HIV Research and TreatmentProtein Structure and Dynamics

Cited by 235

3′‐Processing and strand transfer catalysed by retroviral integrase in crystallo

Hare, S., Maertens, G. N., & Cherepanov, P. (2012) · The EMBO Journal

HIV/AIDS drug development and treatmentHIV Research and Treatment

Cited by 153

Bromo- and Extraterminal Domain Chromatin Regulators Serve as Cofactors for Murine Leukemia Virus Integration

Gupta, S. S., Maetzig, T., Maertens, G. N., Sharif, A., Rothe, M., Weidner-Glunde, M., Galla, M., Schambach, A., Cherepanov, P., & Schulz, T. F. (2013) · Journal of Virology

Virus-based gene therapy researchHIV Research and Treatment

Cited by 139

Structure and function of retroviral integrase

Maertens, G. N., Engelman, A. N., & Cherepanov, P. (2022) · Nature Reviews Microbiology

HIV/AIDS drug development and treatmentHIV Research and Treatment

Cited by 124

Key determinants of target DNA recognition by retroviral intasomes

Serrao, E., Ballandras-Colas, A., Cherepanov, P., Maertens, G. N., & Engelman, A. N. (2015) · Retrovirology

Virus-based gene therapy researchHIV Research and Treatment

Cited by 62

Integrase residues that determine nucleotide preferences at sites of HIV-1 integration: implications for the mechanism of target DNA binding

Serrao, E., Krishnan, L., Shun, M.-C., Li, X., Cherepanov, P., Engelman, A., & Maertens, G. N. (2014) · Nucleic Acids Research

HIV Research and TreatmentHIV/AIDS drug development and treatment

Cited by 59

B′-protein phosphatase 2A is a functional binding partner of delta-retroviral integrase

Maertens, G. N. (2016) · Nucleic Acids Research

T-cell and Retrovirus StudiesHIV Research and Treatment

Cited by 38

Inhibition of HTLV-1 Infection by HIV-1 First- and Second-Generation Integrase Strand Transfer Inhibitors

Barski, M. S., Minnell, J. J., & Maertens, G. N. (2019) · Frontiers in Microbiology

T-cell and Retrovirus StudiesHIV/AIDS drug development and treatment

Cited by 37

Cryo-EM structure of the deltaretroviral intasome in complex with the PP2A regulatory subunit B56γ

Barski, M. S., Minnell, J. J., Hodakova, Z., Pye, V. E., Nans, A., Cherepanov, P., & Maertens, G. N. (2020) · Nature Communications

T-cell and Retrovirus StudiesHIV Research and Treatment

Cited by 29

Virus–Host Interactions in Retrovirus Integration

Engelman, A. N., & Maertens, G. N. (2018) · Retrovirus-Cell Interactions

Virus-based gene therapy researchHIV Research and Treatment

Cited by 12