Naisbitt, Dean J.

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME

Godoy, P., Hewitt, N. J., Albrecht, U., Andersen, M. E., Ansari, N., Bhattacharya, S., Bode, J. G., Bolleyn, J., Borner, C., Böttger, J., et al. (2013) · Archives of Toxicology

Drug-Induced Hepatotoxicity and ProtectionLiver physiology and pathology

Cited by 1,280

Covalent binding of the nitroso metabolite of sulfamethoxazole leads to toxicity and major histocompatibility complex-restricted antigen presentation

Naisbitt, D. J., Farrell, J., Gordon, S. F., Maggs, J. L., Burkhart, C., Pichler, W. J., Pirmohamed, M., & Park, B. K. (2002) · Molecular Pharmacology

Drug-Induced Adverse ReactionsImmunotoxicology and immune responses

Cited by 141

Antigenicity and immunogenicity of sulphamethoxazole: demonstration of metabolism‐dependent haptenation and T‐cell proliferation in vivo

Naisbitt, D. J., Gordon, S. F., Pirmohamed, M., Burkhart, C., Cribb, A. E., Pichler, W. J., & Park, B. K. (2001) · British Journal of Pharmacology

Drug-Induced Adverse ReactionsContact Dermatitis and Allergies

Cited by 133

Generation and characterization of antigen-specific CD4+, CD8+, and CD4+CD8+ T-cell clones from patients with carbamazepine hypersensitivity

Wu, Y., Farrell, J., Pirmohamed, M., Park, B. K., & Naisbitt, D. J. (2007) · Journal of Allergy and Clinical Immunology

Drug-Induced Adverse ReactionsT-cell and B-cell Immunology

Cited by 115

Multiple Adduction Reactions of Nitroso Sulfamethoxazole with Cysteinyl Residues of Peptides and Proteins: Implications for Hapten Formation

Callan, H. E., Jenkins, R. E., Maggs, J. L., Lavergne, S. N., Clarke, S. E., Naisbitt, D. J., & Park, B. K. (2009) · Chemical Research in Toxicology

Drug-Induced Adverse ReactionsContact Dermatitis and Allergies

Cited by 84

Definition of Haptens Derived from Sulfamethoxazole: In Vitro and in Vivo

Tailor, A., Waddington, J. C., Hamlett, J., Maggs, J., Kafu, L., Farrell, J., Dear, G. J., Whitaker, P., Naisbitt, D. J., Park, K., et al. (2019) · Chemical Research in Toxicology

Drug-Induced Adverse ReactionsContact Dermatitis and Allergies

Cited by 26

Nonenzymatic formation of a novel hydroxylated sulfamethoxazole derivative in human liver microsomes: implications for bioanalysis of sulfamethoxazole metabolites

Sanderson, J. P., Hollis, F. J., Maggs, J. L., Clarke, S. E., Naisbitt, D. J., & Park, B. K. (2008) · Drug Metabolism and Disposition

Pharmacogenetics and Drug MetabolismDrug-Induced Adverse Reactions

Cited by 8