Minato, Nagahiro

Development of Lupus-like Autoimmune Diseases by Disruption of the PD-1 Gene Encoding an ITIM Motif-Carrying Immunoreceptor

Nishimura, H., Nose, M., Hiai, H., Minato, N., & Honjo, T. (1999) · Immunity

Systemic Lupus Erythematosus ResearchT-cell and B-cell Immunology

Cited by 2,749

Autoimmune Dilated Cardiomyopathy in PD-1 Receptor-Deficient Mice

Nishimura, H., Okazaki, T., Tanaka, Y., Nakatani, K., Hara, M., Matsumori, A., Sasayama, S., Mizoguchi, A., Hiai, H., Minato, N., et al. (2001) · Science

Viral Infections and Immunology ResearchCardiac Fibrosis and Remodeling

Cited by 1,868

Programmed cell death 1 ligand 1 and tumor-infiltrating CD8 + T lymphocytes are prognostic factors of human ovarian cancer

Hamanishi, J., Mandai, M., Iwasaki, M., Okazaki, T., Tanaka, Y., Yamaguchi, K., Higuchi, T., Yagi, H., Takakura, K., Minato, N., et al. (2007) · Proceedings of the National Academy of Sciences

Cancer Immunotherapy and BiomarkersOvarian cancer diagnosis and treatment

Cited by 1,378

Autoantibodies against cardiac troponin I are responsible for dilated cardiomyopathy in PD-1-deficient mice

Okazaki, T., Tanaka, Y., Nishio, R., Mitsuiye, T., Mizoguchi, A., Wang, J., Ishida, M., Hiai, H., Matsumori, A., Minato, N., et al. (2003) · Nature Medicine

Viral Infections and Immunology ResearchCardiomyopathy and Myosin Studies

Cited by 689

Identification of the von Hippel–Lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex

Iwai, K., Yamanaka, K., Kamura, T., Minato, N., Conaway, R. C., Conaway, J. W., Klausner, R. D., & Pause, A. (1999) · Proceedings of the National Academy of Sciences

Ubiquitin and proteasome pathwaysRenal cell carcinoma treatment

Cited by 508

The 4F2hc/LAT1 complex transports l-DOPA across the blood–brain barrier

Kageyama, T., Nakamura, M., Matsuo, A., Yamasaki, Y., Takakura, Y., Hashida, M., Kanai, Y., Naito, M., Tsuruo, T., Minato, N., et al. (2000) · Brain Research

Amino Acid Enzymes and MetabolismBarrier Structure and Function Studies

Cited by 298

Iron-dependent oxidation, ubiquitination, and degradation of iron regulatory protein 2: Implications for degradation of oxidized proteins

Iwai, K., Drake, S. K., Wehr, N. B., Weissman, A. M., LaVaute, T., Minato, N., Klausner, R. D., Levine, R. L., & Rouault, T. A. (1998) · Proceedings of the National Academy of Sciences

Iron Metabolism and DisordersUbiquitin and proteasome pathways

Cited by 293

Obesity accelerates T cell senescence in murine visceral adipose tissue

Shirakawa, K., Yan, X., Shinmura, K., Endo, J., Kataoka, M., Katsumata, Y., Yamamoto, T., Anzai, A., Isobe, S., Yoshida, N., et al. (2016) · Journal of Clinical Investigation

Adipokines, Inflammation, and Metabolic DiseasesT-cell and B-cell Immunology

Cited by 271

Pyramidal neurons of upper cortical layers generated by NEX-positive progenitor cells in the subventricular zone

Wu, S.-X., Goebbels, S., Nakamura, K., Nakamura, K., Kometani, K., Minato, N., Kaneko, T., Nave, K.-A., & Tamamaki, N. (2005) · Proceedings of the National Academy of Sciences

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

Cited by 198

Identification of the ubiquitin–protein ligase that recognizes oxidized IRP2

Yamanaka, K., Ishikawa, H., Megumi, Y., Tokunaga, F., Kanie, M., Rouault, T. A., Morishima, I., Minato, N., Ishimori, K., & Iwai, K. (2003) · Nature Cell Biology

Ubiquitin and proteasome pathwaysIron Metabolism and Disorders

Cited by 181

Heterogeneous fibroblasts underlie age-dependent tertiary lymphoid tissues in the kidney

Sato, Y., Mii, A., Hamazaki, Y., Fujita, H., Nakata, H., Masuda, K., Nishiyama, S., Shibuya, S., Haga, H., Ogawa, O., et al. (2016) · JCI Insight

Acute Kidney Injury ResearchChronic Kidney Disease and Diabetes

Cited by 148

The impact of senescence-associated T cells on immunosenescence and age-related disorders

Fukushima, Y., Minato, N., & Hattori, M. (2018) · Inflammation and Regeneration

T-cell and B-cell ImmunologyTelomeres, Telomerase, and Senescence

Cited by 118

A CD153+CD4+ T Follicular Cell Population with Cell-Senescence Features Plays a Crucial Role in Lupus Pathogenesis via Osteopontin Production

Tahir, S., Fukushima, Y., Sakamoto, K., Sato, K., Fujita, H., Inoue, J., Uede, T., Hamazaki, Y., Hattori, M., & Minato, N. (2015) · The Journal of Immunology

Systemic Lupus Erythematosus ResearchT-cell and B-cell Immunology

Cited by 113

Prethymic T‐cell development defined by the expression of paired immunoglobulin‐like receptors

Masuda, K., Kubagawa, H., Ikawa, T., Chen, C., Kakugawa, K., Hattori, M., Kageyama, R., Cooper, M. D., Minato, N., Katsura, Y., et al. (2005) · The EMBO Journal

T-cell and B-cell ImmunologyDevelopmental Biology and Gene Regulation

Cited by 79

T Cell Lineage Determination Precedes the Initiation of TCR β Gene Rearrangement

Masuda, K., Kakugawa, K., Nakayama, T., Minato, N., Katsura, Y., & Kawamoto, H. (2007) · The Journal of Immunology

T-cell and B-cell ImmunologyDevelopmental Biology and Gene Regulation

Cited by 77