Schell, John C.

A Mitochondrial Pyruvate Carrier Required for Pyruvate Uptake in Yeast, Drosophila , and Humans

Bricker, D. K., Taylor, E. B., Schell, J. C., Orsak, T., Boutron, A., Chen, Y.-C., Cox, J. E., Cardon, C. M., Van Vranken, J. G., Dephoure, N., et al. (2012) · Science

Mitochondrial Function and PathologyMetabolism and Genetic Disorders

Cited by 843

A Role for the Mitochondrial Pyruvate Carrier as a Repressor of the Warburg Effect and Colon Cancer Cell Growth

Schell, J. C., Olson, K. A., Jiang, L., Hawkins, A. J., Van Vranken, J. G., Xie, J., Egnatchik, R. A., Earl, E. G., DeBerardinis, R. J., & Rutter, J. (2014) · Molecular Cell

Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer

Cited by 363

Control of intestinal stem cell function and proliferation by mitochondrial pyruvate metabolism

Schell, J. C., Wisidagama, D. R., Bensard, C., Zhao, H., Wei, P., Tanner, J., Flores, A., Mohlman, J., Sorensen, L. K., Earl, C. S., et al. (2017) · Nature Cell Biology

Metabolism, Diabetes, and CancerCancer, Hypoxia, and Metabolism

Cited by 322

Lactate dehydrogenase activity drives hair follicle stem cell activation

Flores, A., Schell, J., Krall, A. S., Jelinek, D., Miranda, M., Grigorian, M., Braas, D., White, A. C., Zhou, J. L., Graham, N. A., et al. (2017) · Nature Cell Biology

Hair Growth and DisordersCancer, Hypoxia, and Metabolism

Cited by 301

Pyruvate and metabolic flexibility: illuminating a path toward selective cancer therapies

Olson, K. A., Schell, J. C., & Rutter, J. (2016) · Trends in Biochemical Sciences

Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer

Cited by 154

The force is strong with this one: metabolism (Over)powers stem cell fate

Wei, P., Dove, K. K., Bensard, C., Schell, J. C., & Rutter, J. (2018) · Trends in Cell Biology

Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer

Cited by 47