Shah, Yatrik M.

Intestinal Hypoxia-Inducible Transcription Factors Are Essential for Iron Absorption following Iron Deficiency

Shah, Y. M., Matsubara, T., Ito, S., Yim, S.-H., & Gonzalez, F. J. (2009) · Cell Metabolism

Iron Metabolism and DisordersErythropoietin and Anemia Treatment

Cited by 431

Spontaneous hepatocarcinogenesis in farnesoid X receptor-null mice

Kim, I., Morimura, K., Shah, Y., Yang, Q., Ward, J. M., & Gonzalez, F. J. (2007) · Carcinogenesis

Drug Transport and Resistance MechanismsLiver physiology and pathology

Cited by 357

Microbial Metabolite Signaling Is Required for Systemic Iron Homeostasis

Das, N. K., Schwartz, A. J., Barthel, G., Inohara, N., Liu, Q., Sankar, A., Hill, D. R., Ma, X., Lamberg, O., Schnizlein, M. K., et al. (2020) · Cell Metabolism

Iron Metabolism and DisordersGut microbiota and health

Cited by 331

Hypoxia-Inducible Factor-2α Mediates the Adaptive Increase of Intestinal Ferroportin During Iron Deficiency in Mice

Taylor, M., Qu, A., Anderson, E. R., Matsubara, T., Martin, A., Gonzalez, F. J., & Shah, Y. M. (2011) · Gastroenterology

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 265

Bile Acids Are Substrates for Amine N-Acyl Transferase Activity by Bile Salt Hydrolase

Patterson, A., Rimal, B., Collins, S., Granda, M., Koo, I., Solanka, S., Hoque, N., Gentry, E., Yan, T., Bisanz, J., et al. (2022) · Nature

Gut microbiota and healthDrug Transport and Resistance Mechanisms

Cited by 252

Pregnane X receptor activation ameliorates DSS-induced inflammatory bowel disease via inhibition of NF-κB target gene expression

Shah, Y. M., Ma, X., Morimura, K., Kim, I., & Gonzalez, F. J. (2007) · American Journal of Physiology-Gastrointestinal and Liver Physiology

Inflammatory Bowel DiseasePeroxisome Proliferator-Activated Receptors

Cited by 231

Hypoxia-inducible factor-1α regulates β cell function in mouse and human islets

Cheng, K., Ho, K., Stokes, R., Scott, C., Lau, S. M., Hawthorne, W. J., O’Connell, P. J., Loudovaris, T., Kay, T. W., Kulkarni, R. N., et al. (2010) · Journal of Clinical Investigation

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 230

HIF-2α activation potentiates oxidative cell death in colorectal cancers by increasing cellular iron

Singhal, R., Mitta, S. R., Das, N. K., Kerk, S. A., Sajjakulnukit, P., Solanki, S., Andren, A., Kumar, R., Olive, K. P., Banerjee, R., et al. (2021) · Journal of Clinical Investigation

Ferroptosis and cancer prognosisCancer, Hypoxia, and Metabolism

Cited by 215

Hepatic hepcidin/intestinal HIF-2α axis maintains iron absorption during iron deficiency and overload

Schwartz, A. J., Das, N. K., Ramakrishnan, S. K., Jain, C., Jurkovic, M. T., Wu, J., Nemeth, E., Lakhal-Littleton, S., Colacino, J. A., & Shah, Y. M. (2018) · Journal of Clinical Investigation

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 203

Hypoxia-inducible factors: a central link between inflammation and cancer

Triner, D., & Shah, Y. M. (2016) · Journal of Clinical Investigation

Cancer, Hypoxia, and MetabolismImmune cells in cancer

Cited by 199

Tumor-selective proteotoxicity of verteporfin inhibits colon cancer progression independently of YAP1

Zhang, H., Ramakrishnan, S. K., Triner, D., Centofanti, B., Maitra, D., Győrffy, B., Sebolt-Leopold, J. S., Dame, M. K., Varani, J., Brenner, D. E., et al. (2015) · Science Signaling

Hippo pathway signaling and YAP/TAZAutophagy in Disease and Therapy

Cited by 196

Hypoxia-inducible factors link iron homeostasis and erythropoiesis

Shah, Y. M., & Xie, L. (2014) · Gastroenterology

Erythropoietin and Anemia TreatmentIron Metabolism and Disorders

Cited by 187

Hypoxia-Inducible Factor Augments Experimental Colitis Through an MIF–Dependent Inflammatory Signaling Cascade

Shah, Y. M., Ito, S., Morimura, K., Chen, C., Yim, S., Haase, V. H., & Gonzalez, F. J. (2008) · Gastroenterology

Inflammatory Bowel DiseaseMacrophage Migration Inhibitory Factor

Cited by 168

Minihepcidin peptides as disease modifiers in mice affected by β-thalassemia and polycythemia vera

Casu, C., Oikonomidou, P. R., Chen, H., Nandi, V., Ginzburg, Y., Prasad, P., Fleming, R. E., Shah, Y. M., Valore, E. V., Nemeth, E., et al. (2016) · Blood

Iron Metabolism and DisordersHemoglobinopathies and Related Disorders

Cited by 148

Metabolic requirement for GOT2 in pancreatic cancer depends on environmental context

Kerk, S. A., Lin, L., Myers, A. L., Sutton, D. J., Andren, A., Sajjakulnukit, P., Zhang, L., Zhang, Y., Jiménez, J. A., Nelson, B. S., et al. (2022) · eLife

Cancer, Hypoxia, and MetabolismPancreatic and Hepatic Oncology Research

Cited by 108

Dual modulation of human hepatic zonation via canonical and non-canonical Wnt pathways

McEnerney, L., Duncan, K., Bang, B.-R., Elmasry, S., Li, M., Miki, T., Ramakrishnan, S. K., Shah, Y. M., & Saito, T. (2017) · Experimental & Molecular Medicine

Liver physiology and pathologyWnt/β-catenin signaling in development and cancer

Cited by 81

Disruption of the Arnt gene in endothelial cells causes hepatic vascular defects and partial embryonic lethality in mice

Yim, S. H., Shah, Y., Tomita, S., Morris, D. H., Gavrilova, O., Lambert, G., Ward, J. M., & Gonzalez, F. J. (2006) · Hepatology

Liver physiology and pathologyAngiogenesis and VEGF in Cancer

Cited by 49

Integrated Multiomics Analysis Identifies Molecular Landscape Perturbations during Hyperammonemia in Skeletal Muscle and Myotubes

Welch, N., Singh, S. S., Kumar, A., Dhruba, S. R., Mishra, S., Sekar, J., Bellar, A., Attaway, A. H., Chelluboyina, A., Willard, B. B., et al. (2021) · Journal of Biological Chemistry

Muscle Physiology and DisordersMitochondrial Function and Pathology

Cited by 17