Inoki, Ken

Guidelines for the use and interpretation of assays for monitoring autophagy

Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J. A., et al. (2012) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

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TSC2 Mediates Cellular Energy Response to Control Cell Growth and Survival

Inoki, K., Zhu, T., & Guan, K.-L. (2003) · Cell

PI3K/AKT/mTOR signaling in cancerTuberous Sclerosis Complex Research

Cited by 3,914

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

Inoki, K., Li, Y., Zhu, T., Wu, J., & Guan, K.-L. (2002) · Nature Cell Biology

PI3K/AKT/mTOR signaling in cancerTuberous Sclerosis Complex Research

Cited by 3,083

Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling

Inoki, K., Li, Y., Xu, T., & Guan, K.-L. (2003) · Genes & Development

PI3K/AKT/mTOR signaling in cancerTuberous Sclerosis Complex Research

Cited by 1,911

TSC2 Integrates Wnt and Energy Signals via a Coordinated Phosphorylation by AMPK and GSK3 to Regulate Cell Growth

Inoki, K., Ouyang, H., Zhu, T., Lindvall, C., Wang, Y., Zhang, X., Yang, Q., Bennett, C., Harada, Y., Stankunas, K., et al. (2006) · Cell

PI3K/AKT/mTOR signaling in cancerTuberous Sclerosis Complex Research

Cited by 1,377

ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS

Alexander, A., Cai, S.-L., Kim, J., Nanez, A., Sahin, M., MacLean, K. H., Inoki, K., Guan, K.-L., Shen, J., Person, M. D., et al. (2010) · Proceedings of the National Academy of Sciences

PI3K/AKT/mTOR signaling in cancerAutophagy in Disease and Therapy

Cited by 717

Spatial Coupling of mTOR and Autophagy Augments Secretory Phenotypes

Narita, M., Young, A. R. J., Arakawa, S., Samarajiwa, S. A., Nakashima, T., Yoshida, S., Hong, S., Berry, L. S., Reichelt, S., Ferreira, M., et al. (2011) · Science

Autophagy in Disease and TherapyPI3K/AKT/mTOR signaling in cancer

Cited by 594

Role of mTOR in podocyte function and diabetic nephropathy in humans and mice

Gödel, M., Hartleben, B., Herbach, N., Liu, S., Zschiedrich, S., Lu, S., Debreczeni-Mór, A., Lindenmeyer, M. T., Rastaldi, M.-P., Hartleben, G., et al. (2011) · Journal of Clinical Investigation

Renal Diseases and GlomerulopathiesChronic Kidney Disease and Diabetes

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mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice

Inoki, K., Mori, H., Wang, J., Suzuki, T., Hong, S., Yoshida, S., Blattner, S. M., Ikenoue, T., Rüegg, M. A., Hall, M. N., et al. (2011) · Journal of Clinical Investigation

Renal Diseases and GlomerulopathiesChronic Kidney Disease and Diabetes

Cited by 538

The Stress-inducted Proteins RTP801 and RTP801L Are Negative Regulators of the Mammalian Target of Rapamycin Pathway

Corradetti, M. N., Inoki, K., & Guan, K.-L. (2005) · Journal of Biological Chemistry

PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer

Cited by 237

TSC1 Stabilizes TSC2 by Inhibiting the Interaction between TSC2 and the HERC1 Ubiquitin Ligase

Chong-Kopera, H., Inoki, K., Li, Y., Zhu, T., Garcia-Gonzalo, F. R., Rosa, J. L., & Guan, K.-L. (2006) · Journal of Biological Chemistry

Tuberous Sclerosis Complex ResearchPI3K/AKT/mTOR signaling in cancer

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Glycolytic Enzymes Coalesce in G Bodies under Hypoxic Stress

Jin, M., Fuller, G. G., Han, T., Yao, Y., Alessi, A. F., Freeberg, M. A., Roach, N. P., Moresco, J. J., Karnovsky, A., Baba, M., et al. (2017) · Cell Reports

Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer

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mTOR pathway as a target in tissue hypertrophy

Lee, C.-H., Inoki, K., & Guan, K.-L. (2007) · Annual Review of Pharmacology and Toxicology

PI3K/AKT/mTOR signaling in cancerTuberous Sclerosis Complex Research

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Macropinocytosis, mTORC1 and cellular growth control

Yoshida, S., Pacitto, R., Inoki, K., & Swanson, J. (2018) · Cellular and Molecular Life Sciences

PI3K/AKT/mTOR signaling in cancerCellular transport and secretion

Cited by 114

Growth factor signaling to mTORC1 by amino acid–laden macropinosomes

Yoshida, S., Pacitto, R., Yao, Y., Inoki, K., & Swanson, J. A. (2015) · Journal of Cell Biology

PI3K/AKT/mTOR signaling in cancerCellular transport and secretion

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