Janssen, Harry L.A.

Levels of alkaline phosphatase and bilirubin are surrogate end points of outcomes of patients with primary biliary cirrhosis: an international follow-up study

Lammers, W. J., van Buuren, H. R., Hirschfield, G. M., Janssen, H. L. A., Invernizzi, P., Mason, A. L., Ponsioen, C. Y., Floreani, A., Corpechot, C., Mayo, M. J., et al. (2014) · Gastroenterology

Liver Diseases and ImmunityPediatric Hepatobiliary Diseases and Treatments

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Development and validation of a scoring system to predict outcomes of patients with primary biliary cirrhosis receiving ursodeoxycholic acid therapy

Lammers, W. J., Hirschfield, G. M., Corpechot, C., Nevens, F., Lindor, K. D., Janssen, H. L. A., Floreani, A., Ponsioen, C. Y., Mayo, M. J., Invernizzi, P., et al. (2015) · Gastroenterology

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Ursodeoxycholic acid therapy and liver transplant-free survival in patients with primary biliary cholangitis

Harms, M. H., van Buuren, H. R., Corpechot, C., Thorburn, D., Janssen, H. L. A., Lindor, K. D., Hirschfield, G. M., Parés, A., Floreani, A., Mayo, M. J., et al. (2019) · Journal of Hepatology

Liver Diseases and ImmunityPediatric Hepatobiliary Diseases and Treatments

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The Rotterdam Study: 2010 objectives and design update

Hofman, A., Breteler, M. M. B., van Duijn, C. M., Janssen, H. L. A., Krestin, G. P., Kuipers, E. J., Stricker, B. H. C., Tiemeier, H., Uitterlinden, A. G., Vingerling, J. R., et al. (2009) · European Journal of Epidemiology

Cardiovascular Health and Risk FactorsHealth, Environment, Cognitive Aging

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Suicide associated with alfa-interferon therapy for chronic viral hepatitis

Janssen, H. L. A., Brouwer, J. T., van der Mast, R. C., & Schalm, S. W. (1994) · Journal of Hepatology

Suicide and Self-Harm StudiesHepatitis C virus research

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Nonalcoholic steatohepatitis is associated with liver-related outcomes and all-cause mortality in chronic hepatitis B

Choi, H. S. J., Brouwer, W. P., Zanjir, W. M. R., de Man, R. A., Feld, J. J., Hansen, B. E., Janssen, H. L. A., & Patel, K. (2020) · Hepatology

Liver Disease Diagnosis and TreatmentHepatitis B Virus Studies

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Thyroid function and the risk of nonalcoholic fatty liver disease: the Rotterdam study

Bano, A., Chaker, L., Plompen, E. P. C., Hofman, A., Dehghan, A., Franco, O. H., Janssen, H. L. A., Murad, S. D., & Peeters, R. P. (2016) · The Journal of Clinical Endocrinology & Metabolism

Liver Disease Diagnosis and TreatmentThyroid Disorders and Treatments

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Simtuzumab for primary sclerosing cholangitis: phase 2 study results with insights on the natural history of the disease

Muir, A. J., Levy, C., Janssen, H. L. A., Montano‐Loza, A. J., Shiffman, M. L., Caldwell, S., Luketic, V., Ding, D., Jia, C., McColgan, B. J., et al. (2019) · Hepatology

Liver Diseases and ImmunityLiver physiology and pathology

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Goals of Treatment for Improved Survival in Primary Biliary Cholangitis: Treatment Target Should Be Bilirubin Within the Normal Range and Normalization of Alkaline Phosphatase

Murillo Perez, C. F., Harms, M. H., Lindor, K. D., van Buuren, H. R., Hirschfield, G. M., Corpechot, C., van der Meer, A. J., Feld, J. J., Gulamhusein, A., Lammers, W. J., et al. (2020) · American Journal of Gastroenterology

Liver Diseases and ImmunityPediatric Hepatobiliary Diseases and Treatments

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Stratification of hepatocellular carcinoma risk in primary biliary cirrhosis: a multicentre international study

Trivedi, P. J., Lammers, W. J., van Buuren, H. R., Parés, A., Floreani, A., Janssen, H. L. A., Invernizzi, P., Battezzati, P. M., Ponsioen, C. Y., Corpechot, C., et al. (2016) · Gut

Liver Diseases and ImmunityHepatocellular Carcinoma Treatment and Prognosis

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Combined ursodeoxycholic acid (UDCA) and fenofibrate in primary biliary cholangitis patients with incomplete UDCA response may improve outcomes

Cheung, A. C., Lapointe‐Shaw, L., Kowgier, M., Meza‐Cardona, J., Hirschfield, G. M., Janssen, H. L. A., & Feld, J. J. (2016) · Alimentary Pharmacology & Therapeutics

Liver Diseases and ImmunityDrug Transport and Resistance Mechanisms

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Optimising risk stratification in primary biliary cirrhosis: AST/platelet ratio index predicts outcome independent of ursodeoxycholic acid response

Trivedi, P. J., Bruns, T., Cheung, A., Li, K.-K., Kittler, C., Kumagi, T., Shah, H., Corbett, C., Al-Harthy, N., Acarsu, U., et al. (2014) · Journal of Hepatology

Liver Diseases and ImmunityLiver Disease and Transplantation

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The potent bile acid sequestrant colesevelam is not effective in cholestatic pruritus: results of a double-blind, randomized, placebo-controlled trial

Kuiper, E. M. M., van Erpecum, K. J., Beuers, U., Hansen, B. E., Thio, B. H., de Man, R. A., Janssen, H. L. A., & van Buuren, H. R. (2010) · Hepatology

Liver Diseases and ImmunityDrug Transport and Resistance Mechanisms

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Dissecting the multifaceted impact of statin use on fatty liver disease: a multidimensional study

Ayada, I., van Kleef, L. A., Zhang, H., Liu, K., Li, P., Abozaid, Y. J., Lavrijsen, M., Janssen, H. L. A., van der Laan, L. J. W., Ghanbari, M., et al. (2023) · EBioMedicine

Liver Disease Diagnosis and TreatmentLipoproteins and Cardiovascular Health

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Re‐evaluation of hepatitis B virus clinical phases by systems biology identifies unappreciated roles for the innate immune response and B cells

Vanwolleghem, T., Hou, J., van Oord, G., Andeweg, A. C., Osterhaus, A. D. M. E., Pas, S. D., Janssen, H. L. A., & Boonstra, A. (2015) · Hepatology

Hepatitis B Virus StudiesHepatitis C virus research

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Greater Transplant-Free Survival in Patients Receiving Obeticholic Acid for Primary Biliary Cholangitis in a Clinical Trial Setting Compared to Real-World External Controls

Murillo Perez, C. F., Fisher, H., Hiu, S., Kareithi, D., Adekunle, F., Mayne, T., Malecha, E., Ness, E., van der Meer, A. J., Lammers, W. J., et al. (2022) · Gastroenterology

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A liver immune rheostat regulates CD8 T cell immunity in chronic HBV infection

Bosch, M., Kallin, N., Donakonda, S., Zhang, J. D., Wintersteller, H., Hegenbarth, S., Heim, K., Ramirez, C., Fürst, A., Lattouf, E. I., et al. (2024) · Nature

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Milder disease stage in patients with primary biliary cholangitis over a 44‐year period: A changing natural history

Murillo Perez, C. F., Goet, J. C., Lammers, W. J., Gulamhusein, A., van Buuren, H. R., Ponsioen, C. Y., Carbone, M., Mason, A., Corpechot, C., Invernizzi, P., et al. (2018) · Hepatology

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Real‐World Effectiveness of Obeticholic Acid in Patients with Primary Biliary Cholangitis

Roberts, S. B., Ismail, M., Kanagalingam, G., Mason, A. L., Swain, M. G., Vincent, C., Yoshida, E. M., Tsien, C., Flemming, J. A., Janssen, H. L. A., et al. (2020) · Hepatology Communications

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Risk of gallbladder cancer in patients with primary sclerosing cholangitis and radiographically detected gallbladder polyps

van Erp, L. W., Cunningham, M., Narasimman, M., Ale Ali, H., Jhaveri, K., Drenth, J. P. H., Janssen, H. L. A., Levy, C., Hirschfield, G. M., Hansen, B. E., et al. (2020) · Liver International

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Optimizing therapy in primary biliary cholangitis: Alkaline phosphatase at six months identifies one‐year non‐responders and predicts survival

Murillo Perez, C. F., Ioannou, S., Hassanally, I., Trivedi, P. J., Corpechot, C., van der Meer, A. J., Lammers, W. J., Battezzati, P. M., Lindor, K. D., Nevens, F., et al. (2023) · Liver International

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A rare missense variant in RCL1 segregates with depression in extended families.

Amin, N., de Vrij, F. M. S., Baghdadi, M., Brouwer, R. W. W., van Rooij, J. G. J., Jovanova, O., Uitterlinden, A. G., Hofman, A., Janssen, H. L. A., Darwish Murad, S., et al. (2018) · Molecular Psychiatry

Genetic Associations and EpidemiologyTreatment of Major Depression

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Metabolic dysfunction-associated steatohepatitis reduces interferon and macrophage liver gene signatures in patients with chronic hepatitis B

Osmani, Z., Brouwer, W. P., Grashof, D. G. B., Lim, Y., Doukas, M., Janssen, H. L. A., van de Werken, H. J. G., & Boonstra, A. (2025) · Journal of Hepatology

Liver Disease Diagnosis and TreatmentHepatitis B Virus Studies

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P1184 : Age, bilirubin and albumin, regardless of sex, are the strongest independent predictors of biochemical response and transplantation-free survival in patients with primary biliary cirrhosis

Cheung, A. C., Lammers, W. J., Hirschfield, G. M., Invernizzi, P., Mason, A. L., Ponsioen, C. Y., Floreani, A., Corpechot, C., Mayo, M. J., Pares, A., et al. (2015) · Journal of Hepatology

Liver Diseases and ImmunityLiver Disease and Transplantation

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