Vandenbroucke, Roosmarijn E.

A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment

Van Hove, H., Martens, L., Scheyltjens, I., De Vlaminck, K., Pombo Antunes, A. R., De Prijck, S., Vandamme, N., De Schepper, S., Van Isterdael, G., Scott, C. L., et al. (2019) · Nature Neuroscience

Neuroinflammation and Neurodegeneration MechanismsSingle-cell and spatial transcriptomics

Cited by 1,074

Single-cell profiling of myeloid cells in glioblastoma across species and disease stage reveals macrophage competition and specialization

Pombo Antunes, A. R., Scheyltjens, I., Lodi, F., Messiaen, J., Antoranz, A., Duerinck, J., Kancheva, D., Martens, L., De Vlaminck, K., Van Hove, H., et al. (2021) · Nature Neuroscience

Immune cells in cancerGlioma Diagnosis and Treatment

Cited by 704

Endothelial LRP1 transports amyloid-β1–42 across the blood-brain barrier

Storck, S. E., Meister, S., Nahrath, J., Meißner, J. N., Schubert, N., Di Spiezio, A., Baches, S., Vandenbroucke, R. E., Bouter, Y., Prikulis, I., et al. (2015) · Journal of Clinical Investigation

Barrier Structure and Function StudiesAlzheimer's disease research and treatments

Cited by 477

The Impact of Systemic Inflammation on Alzheimer’s Disease Pathology

Xie, J., Van Hoecke, L., & Vandenbroucke, R. E. (2022) · Frontiers in Immunology

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 324

Friends or foes: matrix metalloproteinases and their multifaceted roles in neurodegenerative diseases

Brkic, M., Balusu, S., Libert, C., & Vandenbroucke, R. E. (2015) · Mediators of Inflammation

Protease and Inhibitor MechanismsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 205

Safety and efficacy of faecal microbiota transplantation in patients with mild to moderate Parkinson's disease (GUT-PARFECT): a double-blind, placebo-controlled, randomised, phase 2 trial

Bruggeman, A., Vandendriessche, C., Hamerlinck, H., De Looze, D., Tate, D. J., Vuylsteke, M., De Commer, L., Devolder, L., Raes, J., Verhasselt, B., et al. (2024) · eClinicalMedicine

Parkinson's Disease Mechanisms and TreatmentsGut microbiota and health

Cited by 139

Mouse models of ageing and their relevance to disease

Kõks, S., Dogan, S., Tuna, B. G., González-Navarro, H., Potter, P., & Vandenbroucke, R. E. (2016) · Mechanisms of Ageing and Development

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 125

Gut microbiota regulates blood‐cerebrospinal fluid barrier function and Aβ pathology

Xie, J., Bruggeman, A., De Nolf, C., Vandendriessche, C., Van Imschoot, G., Van Wonterghem, E., Vereecke, L., & Vandenbroucke, R. E. (2023) · The EMBO Journal

Barrier Structure and Function StudiesGut microbiota and health

Cited by 125

Caloric restriction: Beneficial effects on brain aging and Alzheimer’s disease

Van Cauwenberghe, C., Vandendriessche, C., Libert, C., & Vandenbroucke, R. E. (2016) · Mammalian Genome

Genetics, Aging, and Longevity in Model OrganismsSirtuins and Resveratrol in Medicine

Cited by 121

The choroid plexus epithelium as a novel player in the stomach-brain axis during Helicobacter infection

Gorlé, N., Blaecher, C., Bauwens, E., Vandendriessche, C., Balusu, S., Vandewalle, J., Van Cauwenberghe, C., Van Wonterghem, E., Van Imschoot, G., Liu, C., et al. (2018) · Brain, Behavior, and Immunity

Helicobacter pylori-related gastroenterology studiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 49