Takubo, Keiyo

Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells

Ito, K., Hirao, A., Arai, F., Takubo, K., Matsuoka, S., Miyamoto, K., Ohmura, M., Naka, K., Hosokawa, K., Ikeda, Y., et al. (2006) · Nature Medicine

Hematopoietic Stem Cell TransplantationRedox biology and oxidative stress

Cited by 1,362

Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells

Ito, K., Hirao, A., Arai, F., Matsuoka, S., Takubo, K., Hamaguchi, I., Nomiyama, K., Hosokawa, K., Sakurada, K., Nakagata, N., et al. (2004) · Nature

Hematopoietic Stem Cell TransplantationDNA Repair Mechanisms

Cited by 1,175

Regulation of the HIF-1α Level Is Essential for Hematopoietic Stem Cells

Takubo, K., Goda, N., Yamada, W., Iriuchishima, H., Ikeda, E., Kubota, Y., Shima, H., Johnson, R. S., Hirao, A., Suematsu, M., et al. (2010) · Cell Stem Cell

Hematopoietic Stem Cell TransplantationCancer, Hypoxia, and Metabolism

Cited by 891

Metabolic Regulation of Hematopoietic Stem Cells in the Hypoxic Niche

Suda, T., Takubo, K., & Semenza, G. L. (2011) · Cell Stem Cell

Hematopoietic Stem Cell TransplantationCancer, Hypoxia, and Metabolism

Cited by 844

UTX maintains the functional integrity of the murine hematopoietic system by globally regulating aging-associated genes

Sera, Y., Nakata, Y., Ueda, T., Yamasaki, N., Koide, S., Kobayashi, H., Ikeda, K.-I., Kobatake, K., Iwasaki, M., Oda, H., et al. (2021) · Blood

Hematopoietic Stem Cell TransplantationEpigenetics and DNA Methylation

Cited by 42

Acquisition of G0 state by CD34-positive cord blood cells after bone marrow transplantation

Shima, H., Takubo, K., Tago, N., Iwasaki, H., Arai, F., Takahashi, T., & Suda, T. (2010) · Experimental Hematology

Hematopoietic Stem Cell TransplantationMesenchymal stem cell research

Cited by 35

RNaseH2A downregulation drives inflammatory gene expression via genomic DNA fragmentation in senescent and cancer cells

Sugawara, S., Okada, R., Loo, T. M., Tanaka, H., Miyata, K., Chiba, M., Kawasaki, H., Katoh, K., Kaji, S., Maezawa, Y., et al. (2022) · Communications Biology

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 23

Quiescence of adult oligodendrocyte precursor cells requires thyroid hormone and hypoxia to activate Runx1

Tokumoto, Y., Tamaki, S., Kabe, Y., Takubo, K., & Suematsu, M. (2017) · Scientific Reports

Neurogenesis and neuroplasticity mechanismsGlioma Diagnosis and Treatment

Cited by 16