Watada, Hirotaka

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Acevedo Arozena, A., Adachi, H., Adams, C. M., Adams, P. D., Adeli, K., et al. (2016) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

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Guidelines for the use and interpretation of assays for monitoring autophagy

Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J. A., et al. (2012) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1

Klionsky, D. J., Abdel-Aziz, A. K., Abdelfatah, S., Abdellatif, M., Abdoli, A., Abel, S., Abeliovich, H., Abildgaard, M. H., Abudu, Y. P., Acevedo-Arozena, A., et al. (2021) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 2,897

Autophagy Is Important in Islet Homeostasis and Compensatory Increase of Beta Cell Mass in Response to High-Fat Diet

Ebato, C., Uchida, T., Arakawa, M., Komatsu, M., Ueno, T., Komiya, K., Azuma, K., Hirose, T., Tanaka, K., Kominami, E., et al. (2008) · Cell Metabolism

Pancreatic function and diabetesAutophagy in Disease and Therapy

Cited by 774

Serotonin regulates pancreatic beta cell mass during pregnancy

Kim, H., Toyofuku, Y., Lynn, F. C., Chak, E., Uchida, T., Mizukami, H., Fujitani, Y., Kawamori, R., Miyatsuka, T., Kosaka, Y., et al. (2010) · Nature Medicine

Pancreatic function and diabetesDiabetes and associated disorders

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Inhibition of Monocyte Adhesion to Endothelial Cells and Attenuation of Atherosclerotic Lesion by a Glucagon-like Peptide-1 Receptor Agonist, Exendin-4

Arakawa, M., Mita, T., Azuma, K., Ebato, C., Goto, H., Nomiyama, T., Fujitani, Y., Hirose, T., Kawamori, R., & Watada, H. (2010) · Diabetes

Atherosclerosis and Cardiovascular DiseasesDiabetes Treatment and Management

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Brachial-Ankle Pulse Wave Velocity and the Risk Prediction of Cardiovascular Disease: An Individual Participant Data Meta-Analysis

Ohkuma, T., Ninomiya, T., Tomiyama, H., Kario, K., Hoshide, S., Kita, Y., Inoguchi, T., Maeda, Y., Kohara, K., Tabara, Y., et al. (2017) · Hypertension

Cardiovascular Health and Disease PreventionCardiovascular Function and Risk Factors

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Effect of Additional Oral Semaglutide vs Sitagliptin on Glycated Hemoglobin in Adults With Type 2 Diabetes Uncontrolled With Metformin Alone or With Sulfonylurea: The PIONEER 3 Randomized Clinical Trial

Rosenstock, J., Allison, D., Birkenfeld, A. L., Blicher, T. M., Deenadayalan, S., Jacobsen, J. B., Serusclat, P., Violante, R., Watada, H., Davies, M., et al. (2019) · JAMA

Diabetes Treatment and ManagementDiabetes Management and Research

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Effect of an intensified multifactorial intervention on cardiovascular outcomes and mortality in type 2 diabetes (J-DOIT3): an open-label, randomised controlled trial

Ueki, K., Sasako, T., Okazaki, Y., Kato, M., Okahata, S., Katsuyama, H., Haraguchi, M., Morita, A., Ohashi, K., Hara, K., et al. (2017) · The Lancet Diabetes & Endocrinology

Diabetes Treatment and ManagementDiabetes, Cardiovascular Risks, and Lipoproteins

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Human IAPP–induced pancreatic β cell toxicity and its regulation by autophagy

Shigihara, N., Fukunaka, A., Hara, A., Komiya, K., Honda, A., Uchida, T., Abe, H., Toyofuku, Y., Tamaki, M., Ogihara, T., et al. (2014) · Journal of Clinical Investigation

Pancreatic function and diabetesAutophagy in Disease and Therapy

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Effects of Pemafibrate, a Novel Selective PPARα Modulator, on Lipid and Glucose Metabolism in Patients With Type 2 Diabetes and Hypertriglyceridemia: A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial

Araki, E., Yamashita, S., Arai, H., Yokote, K., Satoh, J., Inoguchi, T., Nakamura, J., Maegawa, H., Yoshioka, N., Tanizawa, Y., et al. (2018) · Diabetes Care

Peroxisome Proliferator-Activated ReceptorsLipoproteins and Cardiovascular Health

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Defective autophagy in vascular smooth muscle cells enhances cell death and atherosclerosis

Osonoi, Y., Mita, T., Azuma, K., Nakajima, K., Masuyama, A., Goto, H., Nishida, Y., Miyatsuka, T., Fujitani, Y., Koike, M., et al. (2018) · Autophagy

Autophagy in Disease and TherapyAtherosclerosis and Cardiovascular Diseases

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Safety and efficacy of once‐weekly semaglutide vs additional oral antidiabetic drugs in Japanese people with inadequately controlled type 2 diabetes: A randomized trial

Kaku, K., Yamada, Y., Watada, H., Abiko, A., Nishida, T., Zacho, J., & Kiyosue, A. (2018) · Diabetes, Obesity and Metabolism

Diabetes Treatment and ManagementDiabetes Management and Research

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In vivo and in vitro inhibition of monocyte adhesion to endothelial cells and endothelial adhesion molecules by eicosapentaenoic acid

Yamada, H., Yoshida, M., Nakano, Y., Suganami, T., Satoh, N., Mita, T., Azuma, K., Itoh, M., Yamamoto, Y., Kamei, Y., et al. (2008) · Arteriosclerosis Thrombosis and Vascular Biology

Fatty Acid Research and HealthAtherosclerosis and Cardiovascular Diseases

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Golgi membrane‐associated degradation pathway in yeast and mammals

Yamaguchi, H., Arakawa, S., Kanaseki, T., Miyatsuka, T., Fujitani, Y., Watada, H., Tsujimoto, Y., & Shimizu, S. (2016) · The EMBO Journal

Autophagy in Disease and TherapyCellular transport and secretion

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Long-term, but not short-term high-fat diet induces fiber composition changes and impaired contractile force in mouse fast-twitch skeletal muscle

Eshima, H., Tamura, Y., Kakehi, S., Kurebayashi, N., Murayama, T., Nakamura, K., Kakigi, R., Okada, T., Sakurai, T., Kawamori, R., et al. (2017) · Physiological Reports

Muscle Physiology and DisordersMuscle metabolism and nutrition

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Global use of SGLT2 inhibitors and GLP-1 receptor agonists in type 2 diabetes. Results from DISCOVER

Arnold, S. V., Tang, F., Cooper, A., Chen, H., Gomes, M. B., Rathmann, W., Shimomura, I., Vora, J., Watada, H., Khunti, K., et al. (2022) · BMC Endocrine Disorders

Diabetes Treatment and ManagementDiabetes Management and Research

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Therapeutic effectiveness of potassium iodine in drug-naïve patients with Graves’ disease: a single-center experience

Uchida, T., Goto, H., Kasai, T., Komiya, K., Takeno, K., Abe, H., Shigihara, N., Sato, J., Honda, A., Mita, T., et al. (2014) · Endocrine

Thyroid Disorders and TreatmentsOphthalmology and Eye Disorders

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Effects of sitagliptin on ectopic fat contents and glucose metabolism in type 2 diabetic patients with fatty liver: A pilot study

Watanabe, T., Tamura, Y., Kakehi, S., Funayama, T., Gastaldelli, A., Takeno, K., Kawaguchi, M., Yamamoto, R., Sato, F., Ikeda, S., et al. (2015) · Journal of Diabetes Investigation

Diabetes Treatment and ManagementLiver Disease Diagnosis and Treatment

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Accumulation of Somatic Mutation in Mitochondrial DNA and Atherosclerosis in Diabetic Patients

NOMIYAMA, T., TANAKA, Y., PIAO, L., HATTORI, N., UCHINO, H., WATADA, H., KAWAMORI, R., & OHTA, S. (2004) · Annals of the New York Academy of Sciences

Mitochondrial Function and PathologyDiabetes, Cardiovascular Risks, and Lipoproteins

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Insulin lispro 25/75 and insulin lispro 50/50 as starter insulin in japanese patients with type 2 diabetes: Subanalysis of the classify randomized trial

Watada, H., Imori, M., Li, P., & Iwamoto, N. (2017) · Endocrine Journal

Diabetes Treatment and ManagementDiabetes Management and Research

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A study of changes in insulin requirements related to the menstrual cycle in Japanese women with type 1 diabetes using the advanced hybrid closed‐loop system

Takagi, E., Kaga, H., Mori, R., Fujikawa, S., Nagashima, H., Kogai, T., Koshibu, M., Sato, J., Nishida, Y., Ikeda, F., et al. (2026) · Journal of Diabetes Investigation

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