Afzal, Veena

Expanded encyclopaedias of DNA elements in the human and mouse genomes

The ENCODE Project Consortium, Abascal, F., Acosta, R., Addleman, N. J., Adrian, J., Afzal, V., Ai, R., Aken, B., Akiyama, J. A., Jammal, O. A., et al. (2020) · Nature

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 2,378

ChIP-seq accurately predicts tissue-specific activity of enhancers

Visel, A., Blow, M. J., Li, Z., Zhang, T., Akiyama, J. A., Holt, A., Plajzer-Frick, I., Shoukry, M., Wright, C., Chen, F., et al. (2009) · Nature

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 1,639

In vivo enhancer analysis of human conserved non-coding sequences

Pennacchio, L. A., Ahituv, N., Moses, A. M., Prabhakar, S., Nobrega, M. A., Shoukry, M., Minovitsky, S., Dubchak, I., Holt, A., Lewis, K. D., et al. (2006) · Nature

Genomics and Chromatin DynamicsDevelopmental Biology and Gene Regulation

Cited by 1,165

Enhancer redundancy provides phenotypic robustness in mammalian development

Osterwalder, M., Barozzi, I., Tissières, V., Fukuda-Yuzawa, Y., Mannion, B. J., Afzal, S. Y., Lee, E. A., Zhu, Y., Plajzer-Frick, I., Pickle, C. S., et al. (2018) · Nature

Genomics and Chromatin DynamicsDevelopmental Biology and Gene Regulation

Cited by 642

Scanning Human Gene Deserts for Long-Range Enhancers

Nobrega, M. A., Ovcharenko, I., Afzal, V., & Rubin, E. M. (2003) · Science

Genomics and Chromatin DynamicsCancer-related molecular mechanisms research

Cited by 608

Rapid and Pervasive Changes in Genome-wide Enhancer Usage during Mammalian Development

Nord, A. S., Blow, M. J., Attanasio, C., Akiyama, J. A., Holt, A., Hosseini, R., Phouanenavong, S., Plajzer-Frick, I., Shoukry, M., Afzal, V., et al. (2013) · Cell

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 375

Single-nucleus analysis of accessible chromatin in developing mouse forebrain reveals cell-type-specific transcriptional regulation

Preissl, S., Fang, R., Huang, H., Zhao, Y., Raviram, R., Gorkin, D. U., Zhang, Y., Sos, B. C., Afzal, V., Dickel, D. E., et al. (2018) · Nature Neuroscience

Single-cell and spatial transcriptomicsGenomics and Chromatin Dynamics

Cited by 332

Germline Chd8 haploinsufficiency alters brain development in mouse

Gompers, A. L., Su-Feher, L., Ellegood, J., Copping, N. A., Riyadh, M. A., Stradleigh, T. W., Pride, M. C., Schaffler, M. D., Wade, A. A., Catta-Preta, R., et al. (2017) · Nature Neuroscience

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 266

Tenascin-X deficiency mimics Ehlers-Danlos syndrome in mice through alteration of collagen deposition

Mao, J. R., Taylor, G., Dean, W. B., Wagner, D. R., Afzal, V., Lotz, J. C., Rubin, E. M., & Bristow, J. (2002) · Nature Genetics

Connective tissue disorders researchSkin and Cellular Biology Research

Cited by 261

A High-Resolution Enhancer Atlas of the Developing Telencephalon

Visel, A., Taher, L., Girgis, H., May, D., Golonzhka, O., Hoch, R. V., McKinsey, G. L., Pattabiraman, K., Silberberg, S. N., Blow, M. J., et al. (2013) · Cell

Genomics and Chromatin DynamicsDevelopmental Biology and Gene Regulation

Cited by 257

Ultraconserved Enhancers Are Required for Normal Development

Dickel, D. E., Ypsilanti, A. R., Pla, R., Zhu, Y., Barozzi, I., Mannion, B. J., Khin, Y. S., Fukuda-Yuzawa, Y., Plajzer-Frick, I., Pickle, C. S., et al. (2018) · Cell

Genomics and Chromatin DynamicsDevelopmental Biology and Gene Regulation

Cited by 190

Knockdown expression and hepatic deficiency reveal an atheroprotective role for SR-BI in liver and peripheral tissues

Huby, T., Doucet, C., Dachet, C., Ouzilleau, B., Ueda, Y., Afzal, V., Rubin, E., Chapman, M. J., & Lesnik, P. (2006) · Journal of Clinical Investigation

Cholesterol and Lipid MetabolismAtherosclerosis and Cardiovascular Diseases

Cited by 124

Supervised enhancer prediction with epigenetic pattern recognition and targeted validation

Sethi, A., Gu, M., Gumusgoz, E., Chan, L., Yan, K.-K., Rozowsky, J., Barozzi, I., Afzal, V., Akiyama, J. A., Plajzer-Frick, I., et al. (2020) · Nature Methods

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 109

Ultraconserved enhancer function does not require perfect sequence conservation

Snetkova, V., Ypsilanti, A. R., Akiyama, J. A., Mannion, B. J., Plajzer-Frick, I., Novak, C. S., Harrington, A. N., Pham, Q. T., Kato, M., Zhu, Y., et al. (2021) · Nature Genetics

Genomics and Chromatin DynamicsDevelopmental Biology and Gene Regulation

Cited by 79