Lavé, Thierry
F. Hoffmann-La Roche AG
6 papers on CoChat
Most cited papers
- Verified
PhRMA CPCDC initiative on predictive models of human pharmacokinetics, part 3: Comparative assessement of prediction methods of human clearance
Ring, B. J., Chien, J. Y., Adkison, K. K., Jones, H. M., Rowland, M., Jones, R. D., Yates, J. W. T., Ku, M. S., Gibson, C. R., He, H., et al. (2011) · Journal of Pharmaceutical Sciences
Pharmaceutical studies and practicesAnimal testing and alternatives
Cited by 206
- Verified
PHRMA CPCDC initiative on predictive models of human pharmacokinetics, part 5: Prediction of plasma concentration–time profiles in human by using the physiologically‐based pharmacokinetic modeling approach
Poulin, P., Jones, R. D. O., Jones, H. M., Gibson, C. R., Rowland, M., Chien, J. Y., Ring, B. J., Adkison, K. K., Ku, M. S., He, H., et al. (2011) · Journal of Pharmaceutical Sciences
Pharmaceutical studies and practicesPharmacogenetics and Drug Metabolism
Cited by 174
- Verified
Prediction of intestinal absorption: comparative assessment of gastroplus™ and idea™
Parrott, N., & Lavé, T. (2002) · European Journal of Pharmaceutical Sciences
Computational Drug Discovery MethodsDrug Solubulity and Delivery Systems
Cited by 170
- Verified
Challenges and opportunities with modelling and simulation in drug discovery and drug development
Lavé, T., Parrott, N., Grimm, H. P., Fleury, A., & Reddy, M. (2007) · Xenobiotica
Pharmaceutical studies and practicesStatistical Methods in Clinical Trials
Cited by 115
- Verified
An Evaluation of the Utility of Physiologically Based Models of Pharmacokinetics in Early Drug Discovery
Parrott, N., Paquereau, N., Coassolo, P., & Lavé, T. (2005) · Journal of Pharmaceutical Sciences
Computational Drug Discovery MethodsPharmacogenetics and Drug Metabolism
Cited by 107
- Verified
Recent developments in using mechanistic cardiac modelling for drug safety evaluation
Davies, M. R., Wang, K., Mirams, G. R., Caruso, A., Noble, D., Walz, A., Lavé, T., Schuler, F., Singer, T., & Polonchuk, L. (2016) · Drug Discovery Today
Cardiac electrophysiology and arrhythmiasAnimal testing and alternatives
Cited by 66
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