Hasel, Philip

Neuroinflammatory astrocyte subtypes in the mouse brain

Hasel, P., Rose, I. V. L., Sadick, J. S., Kim, R. D., & Liddelow, S. A. (2021) · Nature Neuroscience

Neuroinflammation and Neurodegeneration MechanismsSingle-cell and spatial transcriptomics

Cited by 586

Neurotoxic reactive astrocytes induce cell death via saturated lipids

Guttenplan, K. A., Weigel, M. K., Prakash, P., Wijewardhane, P. R., Hasel, P., Rufen-Blanchette, U., Münch, A. E., Blum, J. A., Fine, J., Neal, M. C., et al. (2021) · Nature

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 578

Astrocytes and oligodendrocytes undergo subtype-specific transcriptional changes in Alzheimer’s disease.

Sadick, J. S., O’Dea, M. R., Hasel, P., Dykstra, T., Faustin, A., & Liddelow, S. A. (2022) · Neuron

Alzheimer's disease research and treatmentsSingle-cell and spatial transcriptomics

Cited by 415

Neuronal development is promoted by weakened intrinsic antioxidant defences due to epigenetic repression of Nrf2

Bell, K. F. S., Al-Mubarak, B., Martel, M.-A., McKay, S., Wheelan, N., Hasel, P., Márkus, N. M., Baxter, P., Deighton, R. F., Serio, A., et al. (2015) · Nature Communications

Genomics, phytochemicals, and oxidative stressRedox biology and oxidative stress

Cited by 191

Synaptic NMDA receptor activity is coupled to the transcriptional control of the glutathione system

Baxter, P. S., Bell, K. F. S., Hasel, P., Kaindl, A. M., Fricker, M., Thomson, D., Cregan, S. P., Gillingwater, T. H., & Hardingham, G. E. (2015) · Nature Communications

Redox biology and oxidative stressGenomics, phytochemicals, and oxidative stress

Cited by 139

Microglial INPP5D limits plaque formation and glial reactivity in the PSAPP mouse model of Alzheimer's disease

Castranio, E. L., Hasel, P., Haure‐Mirande, J., Ramirez Jimenez, A. V., Hamilton, B. W., Kim, R. D., Glabe, C. G., Wang, M., Zhang, B., Gandy, S., et al. (2023) · Alzheimer's & Dementia

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 74

Defining the molecular identity and morphology of glia limitans superficialis astrocytes in mouse and human

Hasel, P., Cooper, M. L., Marchildon, A. E., Rufen-Blanchette, U. A., Kim, R. D., Ma, T. C., Kang, U. J., Chao, M. V., & Liddelow, S. A. (2023) · Cell Reports

Neuroinflammation and Neurodegeneration MechanismsBarrier Structure and Function Studies

Cited by 47

The Developmental Shift of NMDA Receptor Composition Proceeds Independently of GluN2 Subunit-Specific GluN2 C-Terminal Sequences

McKay, S., Ryan, T. J., McQueen, J., Indersmitten, T., Marwick, K. F. M., Hasel, P., Kopanitsa, M. V., Baxter, P. S., Martel, M.-A., Kind, P. C., et al. (2018) · Cell Reports

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 42