Cudkowicz, Merit E.

Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS

Miller, T. M., Cudkowicz, M. E., Genge, A., Shaw, P. J., Sobue, G., Bucelli, R. C., Chiò, A., Van Damme, P., Ludolph, A. C., Glass, J. D., et al. (2022) · New England Journal of Medicine

Amyotrophic Lateral Sclerosis ResearchNeurogenetic and Muscular Disorders Research

Cited by 966

An antisense oligonucleotide against SOD1 delivered intrathecally for patients with SOD1 familial amyotrophic lateral sclerosis: a phase 1, randomised, first-in-man study

Miller, T. M., Pestronk, A., David, W., Rothstein, J., Simpson, E., Appel, S. H., Andres, P. L., Mahoney, K., Allred, P., Alexander, K., et al. (2013) · The Lancet Neurology

Amyotrophic Lateral Sclerosis ResearchNeurogenetic and Muscular Disorders Research

Cited by 617

Phase 1–2 Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS

Miller, T., Cudkowicz, M., Shaw, P. J., Andersen, P. M., Atassi, N., Bucelli, R. C., Genge, A., Glass, J., Ladha, S., Ludolph, A. L., et al. (2020) · New England Journal of Medicine

Amyotrophic Lateral Sclerosis ResearchAlzheimer's disease research and treatments

Cited by 565

Trial of Sodium Phenylbutyrate–Taurursodiol for Amyotrophic Lateral Sclerosis

Paganoni, S., Macklin, E. A., Hendrix, S., Berry, J. D., Elliott, M. A., Maiser, S., Karam, C., Caress, J. B., Owegi, M. A., Quick, A., et al. (2020) · New England Journal of Medicine

Amyotrophic Lateral Sclerosis ResearchAlzheimer's disease research and treatments

Cited by 536

Modulating inflammatory monocytes with a unique microRNA gene signature ameliorates murine ALS

Butovsky, O., Siddiqui, S., Gabriely, G., Lanser, A. J., Dake, B., Murugaiyan, G., Doykan, C. E., Wu, P. M., Gali, R. R., Iyer, L. K., et al. (2012) · Journal of Clinical Investigation

Amyotrophic Lateral Sclerosis ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 481

Rate of functional decline in Huntington’s disease

Marder, K., Zhao, H., Myers, R. H., Cudkowicz, M., Kayson, E., Kieburtz, K., Orme, C., Paulsen, J., Penney, J. B., Siemers, E., et al. (2000) · Neurology

Genetic Neurodegenerative DiseasesDeep Brain Stimulation and Movement Disorders

Cited by 362

Targeting mi R‐155 restores abnormal microglia and attenuates disease in SOD 1 mice

Butovsky, O., Jedrychowski, M. P., Cialic, R., Krasemann, S., Murugaiyan, G., Fanek, Z., Greco, D. J., Wu, P. M., Doykan, C. E., Kiner, O., et al. (2015) · Annals of Neurology

Amyotrophic Lateral Sclerosis ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 358

Sodium phenylbutyrate prolongs survival and regulates expression of anti-apoptotic genes in transgenic amyotrophic lateral sclerosis mice

Ryu, H., Smith, K., Camelo, S. I., Carreras, I., Lee, J., Iglesias, A. H., Dangond, F., Cormier, K. A., Cudkowicz, M. E., H. Brown, R., et al. (2005) · Journal of Neurochemistry

Amyotrophic Lateral Sclerosis ResearchAlzheimer's disease research and treatments

Cited by 353

Antisense oligonucleotides extend survival and reverse decrement in muscle response in ALS models

McCampbell, A., Cole, T., Wegener, A. J., Tomassy, G. S., Setnicka, A., Farley, B. J., Schoch, K. M., Hoye, M. L., Shabsovich, M., Sun, L., et al. (2018) · Journal of Clinical Investigation

Amyotrophic Lateral Sclerosis ResearchNeurogenetic and Muscular Disorders Research

Cited by 279

SOD1 Suppression with Adeno-Associated Virus and MicroRNA in Familial ALS

Mueller, C., Berry, J. D., McKenna-Yasek, D. M., Gernoux, G., Owegi, M. A., Pothier, L. M., Douthwright, C. L., Gelevski, D., Luppino, S. D., Blackwood, M., et al. (2020) · New England Journal of Medicine

Amyotrophic Lateral Sclerosis ResearchNeurogenetic and Muscular Disorders Research

Cited by 264

Increased in vivo glial activation in patients with amyotrophic lateral sclerosis: Assessed with [11C]-PBR28

Zürcher, N. R., Loggia, M. L., Lawson, R., Chonde, D. B., Izquierdo-Garcia, D., Yasek, J. E., Akeju, O., Catana, C., Rosen, B. R., Cudkowicz, M. E., et al. (2015) · NeuroImage: Clinical

Amyotrophic Lateral Sclerosis ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 226

Prospective study of military service and mortality from ALS

Weisskopf, M. G., O’Reilly, E. J., McCullough, M. L., Calle, E. E., Thun, M. J., Cudkowicz, M., & Ascherio, A. (2005) · Neurology

Amyotrophic Lateral Sclerosis ResearchOccupational Health and Performance

Cited by 197

Safety and efficacy of lithium in combination with riluzole for treatment of amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled trial

Aggarwal, S. P., Zinman, L., Simpson, E., McKinley, J., Jackson, K. E., Pinto, H., Kaufman, P., Conwit, R. A., Schoenfeld, D., Shefner, J., et al. (2010) · The Lancet Neurology

Amyotrophic Lateral Sclerosis ResearchAlzheimer's disease research and treatments

Cited by 195

Long‐term survival of participants in the CENTAUR trial of sodium phenylbutyrate‐taurursodiol in amyotrophic lateral sclerosis

Paganoni, S., Hendrix, S., Dickson, S. P., Knowlton, N., Macklin, E. A., Berry, J. D., Elliott, M. A., Maiser, S., Karam, C., Caress, J. B., et al. (2021) · Muscle & Nerve

Amyotrophic Lateral Sclerosis ResearchNeurogenetic and Muscular Disorders Research

Cited by 180

Tolerance of high‐dose (3,000 mg/day) coenzyme Q10 in ALS

Ferrante, K. L., Shefner, J., Zhang, H., Betensky, R., O'Brien, M., Yu, H., Fantasia, M., Taft, J., Beal, M. F., Traynor, B., et al. (2005) · Neurology

Coenzyme Q10 studies and effectsAmyotrophic Lateral Sclerosis Research

Cited by 154

Quantification of reverse transcriptase in ALS and elimination of a novel retroviral candidate

McCormick, A. L., Brown, R. H., Cudkowicz, M. E., Al-Chalabi, A., & Garson, J. A. (2008) · Neurology

Amyotrophic Lateral Sclerosis ResearchT-cell and Retrovirus Studies

Cited by 117

Identification of Therapeutic Targets for Amyotrophic Lateral Sclerosis Using PandaOmics – An AI-Enabled Biological Target Discovery Platform

Pun, F. W., Liu, B. H. M., Long, X., Leung, H. W., Leung, G. H. D., Mewborne, Q. T., Gao, J., Shneyderman, A., Ozerov, I. V., Wang, J., et al. (2022) · Frontiers in Aging Neuroscience

Amyotrophic Lateral Sclerosis ResearchComputational Drug Discovery Methods

Cited by 115

Combination therapy using minocycline and coenzyme Q10 in R6/2 transgenic Huntington's disease mice

Stack, E. C., Smith, K. M., Ryu, H., Cormier, K., Chen, M., Hagerty, S. W., Del Signore, S. J., Cudkowicz, M. E., Friedlander, R. M., & Ferrante, R. J. (2006) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Genetic Neurodegenerative DiseasesCoenzyme Q10 studies and effects

Cited by 114

Detection of serum reverse transcriptase activity in patients with ALS and unaffected blood relatives

Steele, A. J., Al-Chalabi, A., Ferrante, K., Cudkowicz, M. E., Brown, R. H., & Garson, J. A. (2005) · Neurology

Amyotrophic Lateral Sclerosis ResearchPrion Diseases and Protein Misfolding

Cited by 112

Amyotrophic lateral sclerosis care and research in the United States during the COVID ‐19 pandemic: Challenges and opportunities

Andrews, J. A., Berry, J. D., Baloh, R. H., Carberry, N., Cudkowicz, M. E., Dedi, B., Glass, J., Maragakis, N. J., Miller, T. M., Paganoni, S., et al. (2020) · Muscle & Nerve

Amyotrophic Lateral Sclerosis ResearchTelemedicine and Telehealth Implementation

Cited by 57

Survival analyses from the CENTAUR trial in amyotrophic lateral sclerosis: Evaluating the impact of treatment crossover on outcomes

Paganoni, S., Watkins, C., Cawson, M., Hendrix, S., Dickson, S. P., Knowlton, N., Timmons, J., Manuel, M., & Cudkowicz, M. (2022) · Muscle & Nerve

Amyotrophic Lateral Sclerosis ResearchStatistical Methods in Clinical Trials

Cited by 48

Risk factors for suicidality in Huntington disease: An analysis of the 2CARE clinical trial

McGarry, A., McDermott, M. P., Kieburtz, K., Fung, W. L. A., McCusker, E., Peng, J., de Blieck, E. A., Cudkowicz, M., & for the Huntington Study Group 2CARE Investigators and Coordinators (2019) · Neurology

Genetic Neurodegenerative DiseasesSuicide and Self-Harm Studies

Cited by 24