Foster, Leonard J.

Recent advances in targeting the “undruggable” proteins: from drug discovery to clinical trials

Xie, X., Yu, T., Li, X., Zhang, N., Foster, L. J., Peng, C., Huang, W., & He, G. (2023) · Signal Transduction and Targeted Therapy

Protein Degradation and InhibitorsComputational Drug Discovery Methods

Cited by 396

Cell type prioritization in single-cell data

Skinnider, M. A., Squair, J. W., Kathe, C., Anderson, M. A., Gautier, M., Matson, K. J. E., Milano, M., Hutson, T. H., Barraud, Q., Phillips, A. A., et al. (2021) · Nature Biotechnology

Single-cell and spatial transcriptomicsGene Regulatory Network Analysis

Cited by 274

Protein synthesis rate is the predominant regulator of protein expression during differentiation

Kristensen, A. R., Gsponer, J., & Foster, L. J. (2013) · Molecular Systems Biology

Advanced Proteomics Techniques and ApplicationsRNA and protein synthesis mechanisms

Cited by 217

Evaluating measures of association for single-cell transcriptomics

Skinnider, M. A., Squair, J. W., & Foster, L. J. (2019) · Nature Methods

Single-cell and spatial transcriptomicsBioinformatics and Genomic Networks

Cited by 145

Binary Interactions of the SNARE Proteins Syntaxin-4, SNAP23, and VAMP-2 and Their Regulation by Phosphorylation

Foster, L. J., Yeung, B., Mohtashami, M., Ross, K., Trimble, W. S., & Klip, A. (1998) · Biochemistry

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 134

Profiling the Escherichia coli membrane protein interactome captured in Peptidisc libraries

Carlson, M. L., Stacey, R. G., Young, J. W., Wason, I. S., Zhao, Z., Rattray, D. G., Scott, N., Kerr, C. H., Babu, M., Foster, L. J., et al. (2019) · eLife

Advanced Proteomics Techniques and ApplicationsBacterial Genetics and Biotechnology

Cited by 74

Prioritization of cell types responsive to biological perturbations in single-cell data with Augur

Squair, J. W., Skinnider, M. A., Gautier, M., Foster, L. J., & Courtine, G. (2021) · Nature Protocols

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 61

Transcriptomic and proteomic host response to Aspergillus fumigatus conidia in an air-liquid interface model of human bronchial epithelium

Toor, A., Culibrk, L., Singhera, G. K., Moon, K.-M., Prudova, A., Foster, L. J., Moore, M. M., Dorscheid, D. R., & Tebbutt, S. J. (2018) · PLOS ONE

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 32

Cheminformatics-Driven Discovery of Selective, Nanomolar Inhibitors for Staphylococcal Pyruvate Kinase

Axerio-Cilies, P., See, R. H., Zoraghi, R., Worral, L., Lian, T., Stoynov, N., Jiang, J., Kaur, S., Jackson, L., Gong, H., et al. (2012) · ACS Chemical Biology

Computational Drug Discovery MethodsSynthesis and Characterization of Heterocyclic Compounds

Cited by 31

On the robustness of graph-based clustering to random network alterations

Stacey, R. G., Skinnider, M. A., & Foster, L. J. (2021) · Molecular & Cellular Proteomics

Bioinformatics and Genomic NetworksComplex Network Analysis Techniques

Cited by 11