Christensen, Søren Tvorup

Overview of Structure and Function of Mammalian Cilia

Satir, P., & Christensen, S. T. (2007) · Annual Review of Physiology

Genetic and Kidney Cyst DiseasesCystic Fibrosis Research Advances

Cited by 1,142

Cellular signalling by primary cilia in development, organ function and disease

Anvarian, Z., Mykytyn, K., Mukhopadhyay, S., Pedersen, L. B., & Christensen, S. T. (2019) · Nature Reviews Nephrology

Genetic and Kidney Cyst DiseasesCystic Fibrosis Research Advances

Cited by 845

PDGFRαα Signaling Is Regulated through the Primary Cilium in Fibroblasts

Schneider, L., Clement, C. A., Teilmann, S. C., Pazour, G. J., Hoffmann, E. K., Satir, P., & Christensen, S. T. (2005) · Current Biology

Genetic and Kidney Cyst DiseasesCystic Fibrosis Research Advances

Cited by 592

Primary cilia as dynamic and diverse signalling hubs in development and disease

Mill, P., Christensen, S. T., & Pedersen, L. B. (2023) · Nature Reviews Genetics

Genetic and Kidney Cyst DiseasesCystic Fibrosis Research Advances

Cited by 417

Directional Cell Migration and Chemotaxis in Wound Healing Response to PDGF-AA are Coordinated by the Primary Cilium in Fibroblasts

Schneider, L., Cammer, M., Lehman, J., Nielsen, S., Guerra, C., Veland, I., Stock, C., Hoffmann, E., Yoder, B., Schwab, A., et al. (2010) · Cellular Physiology and Biochemistry

Genetic and Kidney Cyst DiseasesCystic Fibrosis Research Advances

Cited by 250

Ins and outs of GPCR signaling in primary cilia

Schou, K. B., Pedersen, L. B., & Christensen, S. T. (2015) · The EMBO Reports

Genetic and Kidney Cyst DiseasesReceptor Mechanisms and Signaling

Cited by 221

Primary cilia and coordination of receptor tyrosine kinase (RTK) signalling

Christensen, S. T., Clement, C. A., Satir, P., & Pedersen, L. B. (2012) · The Journal of Pathology

Genetic and Kidney Cyst DiseasesCystic Fibrosis Research Advances

Cited by 181

Primary Cilia and Coordination of Receptor Tyrosine Kinase (RTK) and Transforming Growth Factor β (TGF-β) Signaling

Christensen, S. T., Morthorst, S. K., Mogensen, J. B., & Pedersen, L. B. (2017) · Cold Spring Harbor Perspectives in Biology

Genetic and Kidney Cyst DiseasesCystic Fibrosis Research Advances

Cited by 125

The Na+/H+ exchanger NHE1 is required for directional migration stimulated via PDGFR-α in the primary cilium

Schneider, L., Stock, C.-M., Dieterich, P., Jensen, B. H., Pedersen, L. B., Satir, P., Schwab, A., Christensen, S. T., & Pedersen, S. F. (2009) · Journal of Cell Biology

Genetic and Kidney Cyst DiseasesIon Transport and Channel Regulation

Cited by 94

PDGFRα signaling in the primary cilium regulates NHE1-dependent fibroblast migration via coordinated differential activity of MEK1/2-ERK1/2-p90RSK and AKT signaling pathways

Clement, D. L., Mally, S., Stock, C., Lethan, M., Satir, P., Schwab, A., Pedersen, S. F., & Christensen, S. T. (2012) · Journal of Cell Science

Genetic and Kidney Cyst DiseasesIon Transport and Channel Regulation

Cited by 94

Cilia and coordination of signaling networks during heart development

Koefoed, K., Veland, I. R., Pedersen, L. B., Larsen, L. A., & Christensen, S. T. (2014) · Organogenesis

Genetic and Kidney Cyst DiseasesCongenital heart defects research

Cited by 84

The intraflagellar transport machinery in ciliary signaling

Mourão, A., Christensen, S. T., & Lorentzen, E. (2016) · Current Opinion in Structural Biology

Genetic and Kidney Cyst DiseasesCystic Fibrosis Research Advances

Cited by 83

KIF13B establishes a CAV1-enriched microdomain at the ciliary transition zone to promote Sonic hedgehog signalling

Schou, K. B., Mogensen, J. B., Morthorst, S. K., Nielsen, B. S., Aleliunaite, A., Serra-Marques, A., Fürstenberg, N., Saunier, S., Bizet, A. A., Veland, I. R., et al. (2017) · Nature Communications

Genetic and Kidney Cyst DiseasesHedgehog Signaling Pathway Studies

Cited by 72

Inversin/Nephrocystin-2 Is Required for Fibroblast Polarity and Directional Cell Migration

Veland, I. R., Montjean, R., Eley, L., Pedersen, L. B., Schwab, A., Goodship, J., Kristiansen, K., Pedersen, S. F., Saunier, S., & Christensen, S. T. (2013) · PLoS ONE

Genetic and Kidney Cyst DiseasesCellular Mechanics and Interactions

Cited by 67

Regulation of ciliary membrane protein trafficking and signalling by kinesin motor proteins

Morthorst, S. K., Christensen, S. T., & Pedersen, L. B. (2018) · The FEBS Journal

Genetic and Kidney Cyst DiseasesCystic Fibrosis Research Advances

Cited by 49

TSC1 and TSC2 regulate cilia length and canonical Hedgehog signaling via different mechanisms

Rosengren, T., Larsen, L. J., Pedersen, L. B., Christensen, S. T., & Møller, L. B. (2018) · Cellular and Molecular Life Sciences

Genetic and Kidney Cyst DiseasesTuberous Sclerosis Complex Research

Cited by 45

PDGFRβ and oncogenic, mutant PDGFRα D842V promote disassembly of primary cilia by a PLCγ and AURKA dependent mechanism

Nielsen, B. S., Malinda, R. R., Schmid, F. M., Pedersen, S. F., Christensen, S. T., & Pedersen, L. B. (2015) · Journal of Cell Science

Genetic and Kidney Cyst DiseasesCystic Fibrosis Research Advances

Cited by 36

DLG1 functions upstream of SDCCAG3 and IFT20 to control ciliary targeting of polycystin-2

Rezi, C. K., Aslanyan, M. G., Diwan, G. D., Cheng, T., Chamlali, M., Junger, K., Anvarian, Z., Lorentzen, E., Pauly, K. B., Afshar-Bahadori, Y., et al. (2024) · EMBO Reports

Genetic and Kidney Cyst DiseasesCystic Fibrosis Research Advances

Cited by 13

Intraflagellar transport protein IFT172 contains a C-terminal ubiquitin-binding U-box-like domain involved in ciliary signaling

Zacharia, N. K., Kuhns, S., Boegholm, N., Christensen, A., Wang, J., Petriman, N. A., Lorentzen, A., Fialova, J. L., Menguy, L., Saunier, S., et al. (2026) · eLife

Genetic and Kidney Cyst DiseasesCystic Fibrosis Research Advances

Cited by 0