Donowitz, Mark

The burden of selected digestive diseases in the United States

Sandler, R. S., Everhart, J. E., Donowitz, M., Adams, E., Cronin, K., Goodman, C., Gemmen, E., Shah, S., Avdic, A., & Rubin, R. (2002) · Gastroenterology

Health Systems, Economic Evaluations, Quality of LifeEconomic and Financial Impacts of Cancer

Cited by 1,512

A primary human macrophage-enteroid co-culture model to investigate mucosal gut physiology and host-pathogen interactions

Noel, G., Baetz, N. W., Staab, J. F., Donowitz, M., Kovbasnjuk, O., Pasetti, M. F., & Zachos, N. C. (2017) · Scientific Reports

Gut microbiota and healthEscherichia coli research studies

Cited by 420

Human Intestinal Enteroids: a New Model To Study Human Rotavirus Infection, Host Restriction, and Pathophysiology

Saxena, K., Blutt, S. E., Ettayebi, K., Zeng, X.-L., Broughman, J. R., Crawford, S. E., Karandikar, U. C., Sastri, N. P., Conner, M. E., Opekun, A. R., et al. (2016) · Journal of Virology

Viral gastroenteritis research and epidemiologyGastrointestinal motility and disorders

Cited by 375

MOLECULAR PHYSIOLOGY OF INTESTINAL N + /H + EXCHANGE

Zachos, N. C., Tse, M., & Donowitz, M. (2005) · Annual Review of Physiology

Ion Transport and Channel RegulationDrug Transport and Resistance Mechanisms

Cited by 365

Enterohemorrhagic Escherichia coli Reduces Mucus and Intermicrovillar Bridges in Human Stem Cell-Derived Colonoids

In, J., Foulke-Abel, J., Zachos, N. C., Hansen, A.-M., Kaper, J. B., Bernstein, H. D., Halushka, M., Blutt, S., Estes, M. K., Donowitz, M., et al. (2016) · Cellular and Molecular Gastroenterology and Hepatology

Escherichia coli research studiesClostridium difficile and Clostridium perfringens research

Cited by 239

Human enteroids as an ex-vivo model of host–pathogen interactions in the gastrointestinal tract

Foulke-Abel, J., In, J., Kovbasnjuk, O., Zachos, N. C., Ettayebi, K., Blutt, S. E., Hyser, J. M., Zeng, X.-L., Crawford, S. E., Broughman, J. R., et al. (2014) · Experimental Biology and Medicine

Viral gastroenteritis research and epidemiologyDigestive system and related health

Cited by 179

Human mini-guts: New insights into intestinal physiology and host–pathogen interactions

In, J. G., Foulke-Abel, J., Estes, M. K., Zachos, N. C., Kovbasnjuk, O., & Donowitz, M. (2016) · Nature Reviews Gastroenterology & Hepatology

Digestive system and related healthGastrointestinal motility and disorders

Cited by 125

Epithelial WNT ligands are essential drivers of intestinal stem cell activation

Zou, W. Y., Blutt, S. E., Zeng, X.-L., Chen, M.-S., Lo, Y.-H., Castillo-Azofeifa, D., Klein, O. D., Shroyer, N. F., Donowitz, M., & Estes, M. K. (2018) · Cell Reports

Wnt/β-catenin signaling in development and cancerDigestive system and related health

Cited by 73

Molecular Basis and Differentiation-Associated Alterations of Anion Secretion in Human Duodenal Enteroid Monolayers

Yin, J., Tse, C.-M., Avula, L. R., Singh, V., Foulke-Abel, J., de Jonge, H. R., & Donowitz, M. (2018) · Cellular and Molecular Gastroenterology and Hepatology

Ion Transport and Channel RegulationDigestive system and related health

Cited by 58

cAMP Stimulates SLC26A3 Activity in Human Colon by a CFTR-Dependent Mechanism That Does Not Require CFTR Activity

Tse, C.-M., Yin, J., Singh, V., Sarker, R., Lin, R., Verkman, A. S., Turner, J. R., & Donowitz, M. (2019) · Cellular and Molecular Gastroenterology and Hepatology

Ion Transport and Channel RegulationCystic Fibrosis Research Advances

Cited by 53

Loss of PI3k Activity of Inositol Polyphosphate Multikinase Impairs PDK1-Mediated AKT Activation, Cell Migration, and Intestinal Homeostasis

Reilly, L., Semenza, E. R., Koshkaryan, G., Mishra, S., Chatterjee, S., Abramson, E., Mishra, P., Sei, Y., Wank, S. A., Donowitz, M., et al. (2023) · iScience

PI3K/AKT/mTOR signaling in cancerProtein Kinase Regulation and GTPase Signaling

Cited by 29