Lee, Ciaran M.

A high-fidelity Cas9 mutant delivered as a ribonucleoprotein complex enables efficient gene editing in human hematopoietic stem and progenitor cells

Vakulskas, C. A., Dever, D. P., Rettig, G. R., Turk, R., Jacobi, A. M., Collingwood, M. A., Bode, N. M., McNeill, M. S., Yan, S., Camarena, J., et al. (2018) · Nature Medicine

CRISPR and Genetic EngineeringVirus-based gene therapy research

Cited by 782

CRISPR/Cas9-based genome editing for disease modeling and therapy: challenges and opportunities for nonviral delivery

Wang, H.-X., Li, M., Lee, C. M., Chakraborty, S., Kim, H.-W., Bao, G., & Leong, K. W. (2017) · Chemical Reviews

CRISPR and Genetic EngineeringRNA Interference and Gene Delivery

Cited by 560

COSMID: A Web-based Tool for Identifying and Validating CRISPR/Cas Off-target Sites

Cradick, T. J., Qiu, P., Lee, C. M., Fine, E. J., & Bao, G. (2014) · Molecular Therapy - Nucleic Acids

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 408

Streptococcus thermophilus CRISPR-cas9 systems enable specific editing of the human genome

Müller, M., Lee, C. M., Gasiunas, G., Davis, T. H., Cradick, T. J., Siksnys, V., Bao, G., Cathomen, T., & Mussolino, C. (2016) · Molecular Therapy

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 254

AAV-CRISPR Gene Editing Is Negated by Pre-existing Immunity to Cas9

Li, A., Tanner, M. R., Lee, C. M., Hurley, A. E., De Giorgi, M., Jarrett, K. E., Davis, T. H., Doerfler, A. M., Bao, G., Beeton, C., et al. (2020) · Molecular Therapy

CRISPR and Genetic EngineeringVirus-based gene therapy research

Cited by 230

Tools for experimental and computational analyses of off-target editing by programmable nucleases

Bao, X. R., Pan, Y., Lee, C. M., Davis, T. H., & Bao, G. (2021) · Nature Protocols

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 106