Rothstein, Jeffrey D.

Presynaptic regulation of astroglial excitatory neurotransmitter transporter GLT1

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Human Stem Cell-Derived Spinal Cord Astrocytes with Defined Mature or Reactive Phenotypes

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Long‐term survival of participants in the CENTAUR trial of sodium phenylbutyrate‐taurursodiol in amyotrophic lateral sclerosis

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G4C2 Repeat RNA Initiates a POM121-Mediated Reduction in Specific Nucleoporins in C9orf72 ALS/FTD

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Nuclear accumulation of CHMP7 initiates nuclear pore complex injury and subsequent TDP-43 dysfunction in sporadic and familial ALS

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CRISPR-Cas9 Screens Identify the RNA Helicase DDX3X as a Repressor of C9ORF72 (GGGGCC)n Repeat-Associated Non-AUG Translation

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MCT1 Deletion in Oligodendrocyte Lineage Cells Causes Late-Onset Hypomyelination and Axonal Degeneration

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Identification of Therapeutic Targets for Amyotrophic Lateral Sclerosis Using PandaOmics – An AI-Enabled Biological Target Discovery Platform

Pun, F. W., Liu, B. H. M., Long, X., Leung, H. W., Leung, G. H. D., Mewborne, Q. T., Gao, J., Shneyderman, A., Ozerov, I. V., Wang, J., et al. (2022) · Frontiers in Aging Neuroscience

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Nuclear pore complexes — a doorway to neural injury in neurodegeneration

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APOE ε4 carriers share immune-related proteomic changes across neurodegenerative diseases

Shvetcov, A., Johnson, E. C. B., Winchester, L. M., Walker, K. A., Wilkins, H. M., Thompson, T. G., Rothstein, J. D., Krish, V., Imam, F. B., The Global Neurodegeneration Proteomics Consortium (GNPC), et al. (2025) · Nature Medicine

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Ribonuclease recruitment using a small molecule reduced c9ALS/FTD r(G 4 C 2 ) repeat expansion in vitro and in vivo ALS models

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Motor neuron-derived microRNAs cause astrocyte dysfunction in amyotrophic lateral sclerosis

Hoye, M. L., Regan, M. R., Jensen, L. A., Lake, A. M., Reddy, L. V., Vidensky, S., Richard, J.-P., Maragakis, N. J., Rothstein, J. D., Dougherty, J. D., et al. (2018) · Brain

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Amyotrophic lateral sclerosis care and research in the United States during the COVID ‐19 pandemic: Challenges and opportunities

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Erratum: Corrigendum: Identification of a unique TGF-β–dependent molecular and functional signature in microglia

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